| ICE family: ICEKp1 | ||||
| ICEKp1 is a well studied ICE. We selected it as a reference and defined ICEKp1 family. We classified any ICE that encodes an integrase gene closely related to int(ICEKp1), defined as over 60% protein homology and that has significant sequence alignment and syntenic 'core' structure into the this family. | ||||
| # | ID | ICE name | Strain | Replicon |
| 1 | 70  | ICEEc1 | Escherichia coli ECOR31 | - |
| 2 | 126 | ICEKp1 | Klebsiella pneumoniae NTUH-K2044 | NC_012731 |
| 3 | 128  | ICEDdaEch586-1 | Dickeya dadantii Ech586 | NC_013592 |
| 4 | 129 | ICEEcoED1a-1 | Escherichia coli ED1a | NC_011745 |
| 5 | 130 | ICECkoBAA-1 | Citrobacter koseri ATCC BAA-895 | NC_009792 |
| 6 | 131 | ICEDzeEch1591-1 | Dickeya zeae Ech1591 | NC_012912 |
| 7 | 132 | ICEEcoUMN026-1 | Escherichia coli UMN026 | NC_011751 |
| 8 | 180 | ICEKpnHS11286-1 | Klebsiella pneumoniae HS11286 | CP003200 |
| 9 | 374 | HPI-ICEEh1 | Enterobacter hormaechei 05-545 | - |
| Data derived from experimental literature | ||||
| Putative ICEs predicted by bioinformatic methods | ||||
| Element | No. of sequences | Download | Alignment |
| Proteins | 423 | Fasta | Multiple protein sequence alignment by MUSCLE online |
| ICEs | 9 | Fasta | Nucleotide sequence comparison by webACT |
| (1) Paauw A et al. (2010). Evolution in quantum leaps: multiple combinatorial transfers of HPI and other genetic modules in Enterobacteriaceae. PLoS One. 5(1):e8662. [PudMed:20084283] |
| (2) Wu KM et al. (2009). Genome sequencing and comparative analysis of Klebsiella pneumoniae NTUH-K2044, a strain causing liver abscess and meningitis. J Bacteriol. 191(14):4492-501. [PudMed:19447910] |
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(3) Lin TL et al. (2008). Characterization of integrative and conjugative element ICEKp1-associated genomic heterogeneity in a Klebsiella pneumoniae strain isolated from a primary liver abscess. J Bacteriol. 190(2):515-26. [PudMed:17981959]
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(4) Schubert S et al. (2004). A novel integrative and conjugative element (ICE) of Escherichia coli: the putative progenitor of the Yersinia high-pathogenicity island. Mol Microbiol. 51(3):837-48. [PudMed:14731283]
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| experimental literature |