TAfinder detailed results

Overview

Job ID 9mizKMmBqU
Sequence name Escherichia coli strain DH5alpha chromosome, complete genome.
Predicted type II

Toxin (Protein)


Predicted family tad (T6025) Predicted domain COG4679 (Tad)
Locus tag C1467_RS09395 Length 112 a.a.
Coordinates 1819807..1820145 (-)

Antitoxin (Protein)


Predicted family ata (AT6025) Predicted domain COG5606 (Ata)
Locus tag C1467_RS09390 Length 96 a.a.
Coordinates 1819527..1819817 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
C1467_RS09375 1816285..1816926 + 642 WP_001295424.1 uridine kinase -
C1467_RS09380 1817018..1817599 + 582 WP_001234767.1 dCTP deaminase -
C1467_RS09385 1817621..1819474 + 1854 WP_001252352.1 outer membrane assembly protein AsmA -
C1467_RS09390 1819527..1819817 - 291 WP_000687871.1 helix-turn-helix domain-containing protein Antitoxin
C1467_RS09395 1819807..1820145 - 339 WP_001227701.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
C1467_RS09400 1820220..1821803 - 1584 WP_000454701.1 TerC family protein -
C1467_RS25190 1822004..1822153 - 150 WP_162829205.1 hypothetical protein -
C1467_RS09405 1822462..1823601 + 1140 WP_000978094.1 polysaccharide export protein Wza -
C1467_RS09410 1823607..1824050 + 444 WP_000482901.1 low molecular weight protein-tyrosine-phosphatase Wzb -

Domains

The domains were predicted by HMMER and were sorted by score.

Toxin

COG4679 (Tad) (E-value: 1.4e-51, Score:171.6)

(6-116)

PF05973 (Gp49) (E-value: 4.7e-43, Score:143.6)

(4-111)

TIGR02683 (upstrm_HI1419) (E-value: 1.8e-07, Score:29.3)

(22-107)

COG3657 (E-value: 2.2e-07, Score:28.8)

(26-106)

COG2026 (RelE) (E-value: 0.0015, Score:16.8)

(3-84)

Antitoxin

COG5606 (Ata) (E-value: 5.1e-41, Score:136.7)

(2-95)

PF13744 (HTH_37) (E-value: 6.9e-12, Score:43.3)

(8-88)

TIGR03070 (couple_hipB) (E-value: 1.1e-05, Score:22.8)

(217-280)

PF13560 (HTH_31) (E-value: 0.00072, Score:16.9)

(25-56)

smart00530 (HTH_XRE) (E-value: 0.0016, Score:16.7)

(17-53)

cd00093 (Xre) (E-value: 0.0097, Score:13.4)

(46-107)

YdaS_antitoxin (YdaS) (E-value: 0.029, Score:12.5)

(10-35)

YdaS_antitoxin (YdaS) (E-value: 280, Score:-0.3)

(25-30)


Sequences

Toxin        


Download         Length: 112 a.a.        Molecular weight: 13251.03 Da        Isoelectric Point: 9.3193

>WP_001227701.1 TA_15 Toxin
MRKKLAFLDTSLDDLRAFPESSRQEIGYQLDRIQQGLNPYDWKPFSTIGPGVREIRTRDA
DGIYRVMYVAKFEEAVYVLHCFQKKTQTTSQSDIDLAKRRYKELVQERKNEN*

Download         Length: 339 bp

>WP_001227701.1 TA_15 Toxin
TCAATTTTCATTTTTCCGCTCCTGAACAAGTTCTTTATAGCGTCGTTTGGCTAAATCAAT
ATCCGATTGACTGGTAGTCTGTGTTTTCTTTTGAAAACAATGCAATACGTAAACCGCTTC
TTCAAATTTTGCGACATACATGACGCGATAGATCCCATCAGCATCGCGAGTACGAATCTC
TCGCACACCAGGGCCGATAGTTGAAAAAGGTTTCCAGTCGTATGGGTTTAACCCTTGTTG
GATCCTGTCGAGTTGATAGCCAATTTCCTGTCGAGACGATTCTGGAAATGCGCGTAAATC
GTCAAGACTGGTATCAAGAAAAGCCAGCTTTTTTCTCAT

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10790.35 Da        Isoelectric Point: 5.5675

>WP_000687871.1 TA_15 Antitoxin
MKIETFDSVWDAVSDTPEQAENMRIRAELVTIINNWIEQQGFSQAQAASALGVTQPRISE
LARGKIQIFSIDKLITMMAHAGLHIQRIEIQYPHAA*

Download         Length: 291 bp

>WP_000687871.1 TA_15 Antitoxin
CTAAGCAGCATGTGGATATTGAATTTCAATACGTTGAATATGCAATCCTGCATGAGCCAT
CATGGTGATCAATTTATCGATACTAAAGATCTGGATCTTACCTCTGGCAAGTTCAGATAT
GCGAGGTTGAGTGACCCCTAAAGCAGAAGCTGCCTGAGCCTGGCTAAACCCTTGTTGTTC
AATCCAGTTATTAATGATCGTTACAAGCTCGGCACGGATCCGCATATTTTCCGCTTGTTC
AGGGGTGTCACTCACCGCATCCCACACACTATCAAAGGTTTCAATTTTCAT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
T6025 Pseudomonas sp. LM13

40

92

0.407
T6038 Paracoccus aminophilus

37.607

93.6

0.389
T10037 Burkholderia pseudomallei K96243

32.967

82.727

0.265
T325 Streptococcus pneumoniae TIGR4

37.5

39.669

0.159
T1067 Haemophilus influenzae Rd KW20

31.169

64.706

0.212
Protein Organism Identities (%) Coverage (%) Ha-value
AT6025 Pseudomonas sp. LM13

31.343

60.36

0.216
AT10075 Caulobacter crescentus NA1000

33.333

20.07

0.196
AT127 Mycobacterium tuberculosis H37Rv

32.558

39.45

0.144