NZ_CP1012751..164754

MGE detailed information

MGE type: Conjugative plasmid        MGE length: 164754 bp
Accession: NZ_CP101275        Location: 1..164754         Organism: Escherichia coli strain EC21Z-014       Replicon: plasmid pEC21Z014-165K


Gene structure


The 5 kb flanking regions of this MGE are displayed.

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
NML17_RS23850 (1) 1..978 + 978 WP_000361611.1 RepB family plasmid replication initiator protein -
NML17_RS23855 (1263) 1263..2003 - 741 WP_001066954.1 tyrosine-type recombinase/integrase -
NML17_RS23860 (2124) 2124..2321 - 198 WP_149796085.1 serine/threonine protein kinase -
NML17_RS23865 (2695) 2695..3597 - 903 WP_001312822.1 hypothetical protein VF
NML17_RS23870 (3666) 3666..4775 - 1110 WP_001696610.1 SDR family oxidoreductase -
NML17_RS23875 (5207) 5207..6160 - 954 WP_000280980.1 Protease 7 VF
NML17_RS23880 (7413) 7413..7953 - 541 Protein_6 IS3 family transposase IS1351 Transposase
NML17_RS23890 (10436) 10436..11623 + 1188 WP_001696612.1 efflux RND transporter periplasmic adaptor subunit -
NML17_RS23895 (11620) 11620..13560 + 1941 WP_001610286.1 Macrolide export ATP-binding/permease protein MacB VF
NML17_RS23900 (13564) 13564..14934 + 1371 WP_001696614.1 efflux transporter outer membrane subunit -
NML17_RS23905 (15265) 15265..16578 + 1314 Protein_11 IS4 family transposase -
NML17_RS23910 (17318) 17318..18106 + 789 WP_001696616.1 hypothetical protein -
NML17_RS23915 (18108) 18108..20372 + 2265 WP_001610298.1 UvrD-helicase domain-containing protein -
NML17_RS23920 (20623) 20623..20727 + 105 Protein_14 IS3 family transposase IS1351 Transposase
NML17_RS23925 (21133) 21133..22478 - 1346 Protein_15 ISNCY family transposase ISLad2 Transposase
NML17_RS23930 (22714) 22714..23085 - 372 WP_072645713.1 hypothetical protein -
NML17_RS23935 (23128) 23128..23595 - 468 WP_001610303.1 hypothetical protein -
NML17_RS23940 (23595) 23595..23864 - 270 WP_001610304.1 hypothetical protein -
NML17_RS23945 (24096) 24096..25493 - 1398 WP_001610305.1 ISNCY family transposase ISKpn21 Transposase
NML17_RS23950 (25801) 25801..25950 - 150 Protein_20 IS3 family transposase IS2 Transposase
NML17_RS23955 (26128) 26128..27321 - 1194 WP_000450494.1 GTP-binding protein -
NML17_RS23965 (29085) 29085..30298 + 1214 WP_162829202.1 IS3 family transposase IS1203 Transposase
NML17_RS23970 (30264) 30264..30674 + 411 WP_254815537.1 hypothetical protein -
NML17_RS23975 (30674) 30674..30936 + 263 Protein_25 IS91 family transposase ISEc37 Transposase
NML17_RS23980 (31141) 31141..32151 + 1011 WP_000487120.1 IS110 family transposase IS1663 Transposase
NML17_RS23985 (32729) 32729..33319 + 591 WP_000086538.1 Tn3 family transposase TnpR_ISSba14 Transposase
NML17_RS23990 (33366) 33366..33524 + 159 Protein_28 integrase core domain-containing protein -
NML17_RS23995 (33674) 33674..34672 + 999 WP_000756335.1 ABC transporter substrate-binding protein -
NML17_RS24000 (34672) 34672..35709 + 1038 WP_000110581.1 Hemin transport system permease protein HmuU VF
NML17_RS24005 (35709) 35709..36470 + 762 WP_000020503.1 Fe(3+) dicitrate transport ATP-binding protein FecE VF
NML17_RS24010 (36527) 36527..37714 + 1188 WP_025999368.1 MFS transporter -
NML17_RS24015 (37792) 37792..38049 - 258 WP_000412701.1 bacteriocin immunity protein -
NML17_RS24020 (38050) 38050..38283 - 234 WP_000451769.1 HNH endonuclease signature motif containing protein -
NML17_RS24025 (38379) 38379..38650 + 272 Protein_35 hypothetical protein -
NML17_RS24030 (38811) 38811..38990 - 180 Protein_36 3'-5' exonuclease -
NML17_RS24035 (39036) 39036..39203 - 168 Protein_37 type II toxin-antitoxin system toxin YacB -
NML17_RS24040 (39200) 39200..40030 + 831 Protein_38 IS66 family transposase ISEc43 Transposase
NML17_RS24045 (40074) 40074..40722 - 649 Protein_39 IS3 family transposase IS1203 Transposase
NML17_RS24050 (40779) 40779..41210 + 432 Protein_40 relaxase NikB -
NML17_RS24055 (41315) 41315..41399 + 85 Protein_41 hypothetical protein -
NML17_RS24060 (41669) 41669..42337 + 669 WP_000155780.1 cysteine hydrolase -
NML17_RS24065 (42343) 42343..43203 + 861 WP_001442105.1 DUF2877 domain-containing protein -
NML17_RS24070 (43298) 43298..44857 + 1560 WP_000865634.1 acyl-CoA synthetase FdrA -
NML17_RS24075 (44854) 44854..46278 + 1425 WP_001093931.1 DUF1116 domain-containing protein -
NML17_RS24080 (46271) 46271..47227 + 957 WP_001696801.1 carbamate kinase -
NML17_RS24085 (47244) 47244..47633 + 390 WP_001696803.1 hypothetical protein -
NML17_RS24090 (47656) 47656..48879 + 1224 WP_024188138.1 cytosine permease -
NML17_RS24095 (48957) 48957..49847 + 891 WP_000470711.1 putative HTH-type transcriptional regulator YahB VF
NML17_RS24100 (50281) 50281..50670 + 390 WP_000595317.1 cytochrome b562 -
NML17_RS24105 (50922) 50922..51910 + 989 Protein_51 hypothetical protein VF
NML17_RS24110 (51884) 51884..52381 + 498 WP_032297276.1 hypothetical protein VF
NML17_RS24115 (53059) 53059..53349 - 291 WP_000633743.1 hypothetical protein -
NML17_RS24120 (53407) 53407..54072 - 666 WP_000536047.1 ProQ/FINO family protein -
NML17_RS24125 (54175) 54175..54453 - 279 Protein_55 serine acetyltransferase -
NML17_RS24135 (55509) 55509..56350 + 842 Protein_57 hypothetical protein -
NML17_RS24140 (56825) 56825..57754 - 930 WP_001084376.1 putative HTH-type transcriptional regulator YahB VF
NML17_RS24145 (58154) 58154..58759 + 606 WP_000066154.1 ankyrin repeat domain-containing protein -
NML17_RS24150 (58845) 58845..59693 + 849 WP_000531854.1 DUF2877 domain-containing protein -
NML17_RS24155 (59653) 59653..61200 + 1548 WP_000027750.1 acyl-CoA synthetase FdrA -
NML17_RS24160 (61200) 61200..62618 + 1419 WP_000084168.1 DUF1116 domain-containing protein -
NML17_RS24165 (62731) 62731..64281 + 1551 WP_001084509.1 hypothetical protein -
NML17_RS24170 (64308) 64308..65270 + 963 WP_000661609.1 carbamate kinase family protein -
NML17_RS24175 (65822) 65822..67399 - 1578 WP_001323889.1 Aerotaxis receptor VF
NML17_RS24180 (67709) 67709..68269 + 561 WP_001161490.1 Tn3 family transposase TnpR_TnAs1 Transposase
NML17_RS24185 (68273) 68273..71239 + 2967 WP_001138014.1 Tn3 family transposase TnpA_TnAs1 Transposase
NML17_RS24190 (71751) 71751..72972 - 1222 Protein_68 ISL3 family transposase ISEc38 Transposase
NML17_RS24195 (73072) 73072..73436 + 365 Protein_69 IS1 family transposase -
NML17_RS24200 (73491) 73491..74273 - 783 WP_001442137.1 IS21 family transposase IS100kyp Transposase
NML17_RS24205 (74270) 74270..75292 - 1023 WP_000255956.1 IS21 family transposase IS100kyp Transposase
NML17_RS24210 (75381) 75381..75728 + 348 Protein_72 IS1-like element IS1A family transposase -
NML17_RS24215 (75744) 75744..76064 - 321 Protein_73 serine acetyltransferase -
NML17_RS24220 (76168) 76168..76455 - 288 WP_000222760.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin Detail
NML17_RS24225 (76452) 76452..76703 - 252 WP_001132900.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin Detail
NML17_RS24230 (77667) 77667..78524 - 858 WP_000774297.1 incFII family plasmid replication initiator RepA -
NML17_RS24235 (78517) 78517..78999 - 483 WP_001273588.1 hypothetical protein -
NML17_RS24240 (78992) 78992..79039 - 48 WP_229471593.1 hypothetical protein -
NML17_RS24245 (79030) 79030..79281 + 252 WP_223195197.1 replication protein RepA -
NML17_RS24250 (79298) 79298..79555 - 258 WP_000083845.1 replication regulatory protein RepA -
NML17_RS24255 (79839) 79839..79988 - 150 WP_001312851.1 Hok/Gef family protein Toxin Detail
- (80032) 80032..80093 + 62 NuclAT_1 - Antitoxin Detail
- (80032) 80032..80093 + 62 NuclAT_1 - Antitoxin Detail
- (80032) 80032..80093 + 62 NuclAT_1 - Antitoxin Detail
- (80032) 80032..80093 + 62 NuclAT_1 - Antitoxin Detail
NML17_RS24260 (80349) 80349..80423 - 75 Protein_82 endonuclease -
NML17_RS24265 (80669) 80669..80881 - 213 WP_001299730.1 ANR family transcriptional regulator -
NML17_RS24270 (81017) 81017..81577 - 561 WP_000139315.1 fertility inhibition protein FinO -
NML17_RS24275 (81680) 81680..82540 - 861 WP_000704513.1 Quorum-quenching protein AidA VF
NML17_RS24280 (82599) 82599..83345 - 747 WP_000205749.1 conjugal transfer pilus acetylase TraX -
NML17_RS24285 (83365) 83365..88635 - 5271 WP_254815535.1 Multifunctional conjugation protein TraI Relaxase
NML17_RS24290 (88717) 88717..88944 + 228 WP_000450520.1 toxin-antitoxin system antitoxin VapB Antitoxin Detail
NML17_RS24295 (88944) 88944..89342 + 399 WP_000911333.1 tRNA(fMet)-specific endonuclease VapC Toxin Detail
NML17_RS24300 (89351) 89351..91504 - 2154 WP_000009379.1 type IV conjugative transfer system coupling protein TraD -
NML17_RS24305 (91757) 91757..92467 - 711 WP_231793510.1 conjugal transfer complement resistance protein TraT -
NML17_RS24310 (92502) 92502..93011 - 510 WP_000628105.1 conjugal transfer entry exclusion protein TraS -
NML17_RS24315 (93008) 93008..95833 - 2826 WP_072652426.1 conjugal transfer mating-pair stabilization protein TraG -
NML17_RS24320 (95830) 95830..97203 - 1374 WP_021532658.1 conjugal transfer pilus assembly protein TraH -
NML17_RS24325 (97190) 97190..97582 - 393 Protein_95 F-type conjugal transfer protein TrbF -
NML17_RS24330 (97569) 97569..97910 - 342 WP_001442101.1 P-type conjugative transfer protein TrbJ -
NML17_RS24335 (97840) 97840..98385 - 546 WP_000059833.1 type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB -
NML17_RS24340 (98372) 98372..98656 - 285 WP_000624108.1 type-F conjugative transfer system pilin chaperone TraQ -
NML17_RS24345 (98737) 98737..99012 + 276 WP_001513501.1 hypothetical protein -
NML17_RS24350 (99014) 99014..99361 - 348 WP_001287907.1 conjugal transfer protein TrbA -
NML17_RS24355 (99377) 99377..100120 - 744 WP_001030378.1 type-F conjugative transfer system pilin assembly protein TraF -
NML17_RS24360 (100113) 100113..100370 - 258 WP_000864318.1 conjugal transfer protein TrbE -
NML17_RS24365 (100397) 100397..102205 - 1809 WP_072645770.1 type-F conjugative transfer system mating-pair stabilization protein TraN -
NML17_RS24370 (102202) 102202..102840 - 639 WP_000777703.1 type-F conjugative transfer system pilin assembly protein TrbC -
NML17_RS24375 (102849) 102849..103841 - 993 WP_000830839.1 conjugal transfer pilus assembly protein TraU -
NML17_RS24380 (103838) 103838..104470 - 633 WP_001203720.1 type-F conjugative transfer system protein TraW -
NML17_RS24385 (104467) 104467..104853 - 387 WP_000099688.1 type-F conjugative transfer system protein TrbI -
NML17_RS24390 (104850) 104850..107477 - 2628 WP_254815536.1 type IV secretion system protein TraC -
NML17_RS24395 (107637) 107637..107858 - 222 WP_001278690.1 conjugal transfer protein TraR -
NML17_RS24400 (107993) 107993..108508 - 516 WP_000809834.1 type IV conjugative transfer system lipoprotein TraV -
NML17_RS24405 (108505) 108505..108756 - 252 WP_001038351.1 conjugal transfer protein TrbG -
NML17_RS24410 (108768) 108768..108965 - 198 WP_001324648.1 conjugal transfer protein TrbD -
NML17_RS24415 (108952) 108952..109531 - 580 Protein_113 conjugal transfer protein TraP -
NML17_RS24420 (109521) 109521..110948 - 1428 WP_000146685.1 F-type conjugal transfer pilus assembly protein TraB -
NML17_RS24425 (110948) 110948..111676 - 729 WP_001230809.1 type-F conjugative transfer system secretin TraK -
NML17_RS24430 (111663) 111663..112229 - 567 WP_000399805.1 type IV conjugative transfer system protein TraE -
NML17_RS24435 (112251) 112251..112562 - 312 WP_000012106.1 type IV conjugative transfer system protein TraL -
NML17_RS24440 (112577) 112577..112942 - 366 WP_000340276.1 type IV conjugative transfer system pilin TraA -
NML17_RS24445 (112976) 112976..113203 - 228 WP_001254386.1 conjugal transfer relaxosome protein TraY -
NML17_RS24450 (113297) 113297..113983 - 687 WP_001825184.1 PAS domain-containing protein -
NML17_RS24455 (114174) 114174..114557 - 384 WP_000124981.1 conjugal transfer relaxosome DNA-binding protein TraM -
NML17_RS24460 (114834) 114834..115481 + 648 WP_001825185.1 hypothetical protein VF
NML17_RS24465 (115778) 115778..116599 - 822 WP_001234469.1 DUF932 domain-containing protein -
NML17_RS24470 (116718) 116718..117005 - 288 WP_000107542.1 hypothetical protein -
NML17_RS24475 (117007) 117007..117328 + 322 Protein_125 hypothetical protein -
NML17_RS24480 (117629) 117629..117748 - 120 WP_227898123.1 Hok/Gef family protein Toxin Detail
NML17_RS24485 (117696) 117696..117809 - 114 Protein_127 DUF5431 family protein -
- (117843) 117843..118054 - 212 NuclAT_0 - Antitoxin Detail
- (117843) 117843..118054 - 212 NuclAT_0 - Antitoxin Detail
- (117843) 117843..118054 - 212 NuclAT_0 - Antitoxin Detail
- (117843) 117843..118054 - 212 NuclAT_0 - Antitoxin Detail
NML17_RS24490 (118065) 118065..118784 - 720 WP_001276275.1 plasmid SOS inhibition protein A -
NML17_RS24495 (118781) 118781..119215 - 435 WP_000845935.1 conjugation system SOS inhibitor PsiB -
NML17_RS24500 (119270) 119270..121228 - 1959 Protein_130 ParB/RepB/Spo0J family partition protein -
NML17_RS24505 (121287) 121287..121520 - 234 WP_001209608.1 DUF905 domain-containing protein -
NML17_RS24510 (121583) 121583..122080 - 498 WP_050427786.1 single-stranded DNA-binding protein -
NML17_RS24515 (122732) 122732..123429 + 698 WP_223155668.1 IS1-like element IS1A family transposase -
NML17_RS24520 (123486) 123486..124625 - 1140 WP_021512276.1 tyrosine-type recombinase/integrase -
NML17_RS24525 (124786) 124786..125697 - 912 WP_001442123.1 hypothetical protein -
NML17_RS24530 (125694) 125694..126692 - 999 WP_000549075.1 IS91 family transposase ISMno24 Transposase
NML17_RS24535 (126755) 126755..127900 + 1146 Protein_137 translesion error-prone DNA polymerase V subunit UmuC -
NML17_RS24540 (128037) 128037..129008 - 972 WP_001233385.1 ParB family protein -
NML17_RS24545 (129005) 129005..130210 - 1206 WP_001442122.1 Plasmid partition protein A VF
NML17_RS24550 (130861) 130861..131562 + 702 WP_032145561.1 replication initiation protein -
NML17_RS24555 (132242) 132242..133048 - 807 WP_000016968.1 site-specific integrase -
NML17_RS24560 (133049) 133049..133354 - 306 WP_001159871.1 type II toxin-antitoxin system toxin CcdB Toxin Detail
NML17_RS24565 (133356) 133356..133574 - 219 WP_000813630.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin Detail
NML17_RS24570 (134164) 134164..134652 + 489 WP_011254646.1 hypothetical protein -
NML17_RS24575 (134686) 134686..135819 - 1134 WP_000545987.1 DUF3800 domain-containing protein -
NML17_RS24580 (135986) 135986..136759 - 774 WP_000905949.1 hypothetical protein -
NML17_RS24585 (136772) 136772..137272 - 501 WP_000528932.1 HEPN family nuclease -
NML17_RS24590 (137537) 137537..137767 + 231 WP_001261278.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
NML17_RS24595 (137764) 137764..138180 + 417 WP_001034046.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NML17_RS24600 (138225) 138225..142019 - 3795 WP_001144732.1 hypothetical protein -
NML17_RS24605 (142400) 142400..142630 + 231 WP_001261286.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin Detail
NML17_RS24610 (142627) 142627..143043 + 417 WP_001034044.1 type II toxin-antitoxin system VapC family toxin Toxin Detail
NML17_RS24615 (143118) 143118..144683 + 1566 WP_001128474.1 AAA family ATPase -
NML17_RS24620 (144668) 144668..145690 + 1023 WP_032174242.1 helicase UvrD -
NML17_RS24630 (147021) 147021..149222 - 2202 WP_000973519.1 Ferric aerobactin receptor VF
NML17_RS24635 (149248) 149248..150581 - 1334 Protein_157 L-lysine N6-monooxygenase VF
NML17_RS24640 (150578) 150578..152320 - 1743 WP_001015721.1 Aerobactin synthase VF
NML17_RS24645 (152320) 152320..153267 - 948 WP_000011910.1 N(6)-hydroxylysine O-acetyltransferase VF
NML17_RS24650 (153268) 153268..154992 - 1725 WP_000602863.1 N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase VF
NML17_RS24655 (155128) 155128..156321 + 1194 WP_000095527.1 MFS transporter -
NML17_RS24660 (156701) 156701..157081 - 381 WP_001318207.1 fluoride efflux transporter CrcB -
NML17_RS24665 (157422) 157422..157835 - 414 Protein_163 phosphopyruvate hydratase -
NML17_RS24670 (157833) 157833..158090 + 258 Protein_164 transposase -
NML17_RS24675 (158324) 158324..159181 - 858 WP_000968140.1 Manganese transport system membrane protein MntB ARG
NML17_RS24680 (159178) 159178..160035 - 858 WP_000992806.1 Manganese transport system membrane protein MntB ARG
NML17_RS24685 (160032) 160032..160859 - 828 WP_000983710.1 Manganese transport system ATP-binding protein MntB VF
NML17_RS24690 (160859) 160859..161773 - 915 WP_000949004.1 putative periplasmic iron-binding protein VF
NML17_RS24695 (162129) 162129..162826 + 698 WP_223155668.1 IS1-like element IS1A family transposase -
NML17_RS24700 (163006) 163006..163519 - 514 Protein_170 DUF4113 domain-containing protein -
NML17_RS24705 (163580) 163580..163684 - 105 Protein_171 AAA family ATPase -
NML17_RS24710 (163686) 163686..164009 - 324 Protein_172 IS21 family transposase IS21 Transposase

Similar MGE(s)


Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.

Detail Organism MGE type Related TA Genome accession Coordinates Mash
distance