MGE detailed information
MGE type: Conjugative plasmid MGE length: 168051 bp
Accession: NZ_CP049102 Location: 1..168051 Organism: Escherichia coli strain EC28 Replicon: plasmid p2
Accession: NZ_CP049102 Location: 1..168051 Organism: Escherichia coli strain EC28 Replicon: plasmid p2
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| G5V60_RS24330 () | 1..978 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| G5V60_RS24335 () | 1263..2003 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| G5V60_RS24340 () | 2124..2312 | - | 189 | WP_001324033.1 | hypothetical protein | - |
| G5V60_RS24345 () | 2686..3588 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| G5V60_RS24350 () | 3657..4766 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| G5V60_RS24355 () | 5199..6152 | - | 954 | WP_000280980.1 | Protease 7 | VF |
| G5V60_RS24360 () | 7425..7583 | - | 159 | WP_001324039.1 | integrase core domain-containing protein | - |
| G5V60_RS24365 () | 7767..8966 | + | 1200 | Protein_7 | IS3 family transposase IS629 | Transposase |
| G5V60_RS24370 () | 9114..9439 | - | 326 | Protein_8 | IS3 family transposase ISLad1 | Transposase |
| G5V60_RS24375 () | 10420..11607 | + | 1188 | WP_000928804.1 | efflux RND transporter periplasmic adaptor subunit | - |
| G5V60_RS24380 () | 11604..13544 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| G5V60_RS24385 () | 13548..14918 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
| G5V60_RS24390 () | 15392..15586 | + | 195 | Protein_12 | IS200/IS605-like element IS200C family transposase | - |
| G5V60_RS24395 () | 15715..16656 | - | 942 | WP_000974762.1 | hypothetical protein | - |
| G5V60_RS24400 () | 16891..18280 | - | 1390 | Protein_14 | ISNCY family transposase ISKpn21 | Transposase |
| G5V60_RS24405 () | 18590..18739 | - | 150 | Protein_15 | IS3 family transposase IS2 | Transposase |
| G5V60_RS24410 () | 18917..20110 | - | 1194 | WP_000450494.1 | GTP-binding protein | - |
| G5V60_RS24415 () | 21352..22080 | - | 729 | Protein_17 | IS3 family transposase IS2 | Transposase |
| G5V60_RS24425 () | 22142..23304 | + | 1163 | WP_088846059.1 | IS3 family transposase ISEc17 | Transposase |
| G5V60_RS24430 () | 23321..23886 | - | 566 | Protein_19 | IS3 family transposase IS2 | Transposase |
| G5V60_RS24435 () | 24466..24759 | + | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| G5V60_RS24440 () | 24817..25016 | - | 200 | Protein_21 | lysis protein | - |
| G5V60_RS24445 () | 25570..26669 | + | 1100 | Protein_22 | IS481 family transposase ISKpn28 | Transposase |
| G5V60_RS24450 () | 27905..29020 | + | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| G5V60_RS24455 () | 29160..32819 | + | 3660 | WP_001389363.1 | Multidrug efflux ATP-binding/permease protein | VF |
| G5V60_RS24460 () | 32923..34152 | + | 1230 | WP_000933678.1 | Enterochelin esterase | VF |
| G5V60_RS24465 () | 34237..35193 | + | 957 | WP_000271274.1 | Ferri-bacillibactin esterase BesA | VF |
| G5V60_RS24470 () | 35238..37415 | - | 2178 | WP_001222185.1 | Ferric enterobactin receptor | VF |
| G5V60_RS24475 () | 38281..39315 | - | 1035 | WP_001190234.1 | 3-deoxy-7-phosphoheptulonate synthase | - |
| G5V60_RS24480 () | 39875..40183 | - | 309 | WP_000377483.1 | hypothetical protein | - |
| G5V60_RS24485 () | 40282..40464 | - | 183 | WP_000969988.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| G5V60_RS24490 () | 40461..40658 | - | 198 | WP_001324224.1 | toxin-antitoxin system protein | Antitoxin Detail |
| G5V60_RS24495 () | 41340..42614 | + | 1275 | WP_000489609.1 | HlyD family secretion protein | - |
| G5V60_RS24500 () | 42589..44703 | + | 2115 | WP_001183604.1 | peptidase domain-containing ABC transporter | - |
| G5V60_RS24505 () | 44873..45184 | - | 312 | WP_001259758.1 | colicin V | - |
| G5V60_RS24510 () | 45162..45398 | - | 237 | WP_001323890.1 | colicin V immunity protein | - |
| G5V60_RS24515 () | 45559..46336 | + | 778 | Protein_36 | Gfo/Idh/MocA family oxidoreductase | - |
| G5V60_RS24520 () | 46338..46607 | + | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| G5V60_RS24525 () | 46604..47584 | + | 981 | WP_001017346.1 | NAD(P)-binding domain-containing protein | - |
| G5V60_RS24530 () | 47651..48040 | + | 390 | WP_001282144.1 | IS66 family transposase ISEc8 | Transposase |
| G5V60_RS24535 () | 48037..48384 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| G5V60_RS24540 () | 48434..49971 | + | 1538 | Protein_41 | IS66 family transposase ISEc8 | Transposase |
| G5V60_RS24545 () | 50011..50277 | + | 267 | Protein_42 | Tn3 family transposase TnpR_TnEc1 | Transposase |
| G5V60_RS24550 () | 50264..50716 | - | 453 | WP_001553770.1 | peptide deformylase | - |
| G5V60_RS24555 () | 50825..54958 | - | 4134 | WP_079399109.1 | Temperature-sensitive hemagglutinin tsh autotransporter | VF |
| G5V60_RS24560 () | 55129..55320 | + | 192 | Protein_45 | IS91 family transposase | - |
| G5V60_RS24565 () | 55288..55503 | - | 216 | Protein_46 | helix-turn-helix transcriptional regulator | - |
| G5V60_RS24570 () | 55599..55856 | + | 258 | Protein_47 | IS3 family transposase IS911 | Transposase |
| G5V60_RS24575 () | 55924..57075 | + | 1152 | WP_001442799.1 | IS30 family transposase IS30D | Transposase |
| G5V60_RS24580 () | 57197..57562 | + | 366 | WP_000124098.1 | hypothetical protein | - |
| G5V60_RS24585 () | 57562..58677 | + | 1116 | Protein_50 | IS91 family transposase IS91 | Transposase |
| G5V60_RS24590 () | 58858..59202 | - | 345 | WP_001553768.1 | hypothetical protein | - |
| G5V60_RS24600 () | 60060..61811 | - | 1752 | Protein_52 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| G5V60_RS24605 () | 61800..62207 | + | 408 | WP_001214976.1 | cysteine hydrolase | - |
| G5V60_RS24610 () | 62345..63229 | + | 885 | WP_000058717.1 | EamA family transporter | - |
| G5V60_RS24615 () | 63261..64460 | - | 1200 | WP_000804064.1 | Tetracycline resistance protein, class C | ARG |
| G5V60_RS24620 () | 64566..65216 | + | 651 | WP_000164043.1 | tetracycline resistance transcriptional repressor TetR(A) | - |
| G5V60_RS24625 () | 65248..65490 | - | 243 | WP_000844627.1 | transposase | - |
| G5V60_RS24630 () | 65548..67062 | - | 1515 | Protein_58 | Tn3 family transposase TnpA_TnAs1 | Transposase |
| G5V60_RS24635 () | 67128..67832 | + | 705 | WP_001067855.1 | IS6 family transposase IS26 | Transposase |
| G5V60_RS24640 () | 67886..68200 | + | 315 | Protein_60 | recombinase family protein | - |
| G5V60_RS24645 () | 68203..71169 | + | 2967 | WP_001138070.1 | Tn3 family transposase | - |
| G5V60_RS24650 () | 71248..72252 | + | 1005 | WP_000427619.1 | IS110 family transposase IS5075 | Transposase |
| G5V60_RS24655 () | 72434..72610 | - | 177 | WP_000954592.1 | Arm DNA-binding domain-containing protein | - |
| G5V60_RS24665 () | 72940..73755 | + | 816 | WP_001043260.1 | Dihydropteroate synthase | ARG |
| G5V60_RS24670 () | 73816..74619 | + | 804 | WP_001082320.1 | Aminoglycoside 3'-phosphotransferase | ARG |
| G5V60_RS24675 () | 74619..75455 | + | 837 | WP_000480972.1 | hypothetical protein | ARG |
| G5V60_RS24680 () | 75686..76546 | - | 861 | WP_000027057.1 | Beta-lactamase TEM | ARG |
| G5V60_RS24685 () | 76729..77286 | - | 558 | WP_001235713.1 | Tn3 family transposase TnpR_Tn3 | Transposase |
| G5V60_RS24690 () | 77450..80455 | + | 3006 | WP_001143760.1 | Tn3 family transposase TnpA_Tn3 | Transposase |
| G5V60_RS24695 () | 80388..80853 | - | 466 | Protein_70 | incFII family plasmid replication initiator RepA | - |
| G5V60_RS24700 () | 80846..81328 | - | 483 | WP_001273588.1 | hypothetical protein | - |
| G5V60_RS24705 () | 81321..81395 | - | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| G5V60_RS24710 () | 81627..81884 | - | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| G5V60_RS24715 () | 82168..82374 | - | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 82361..82422 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 82361..82422 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 82361..82422 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 82361..82422 | + | 62 | NuclAT_1 | - | Antitoxin Detail |
| G5V60_RS25755 () | 82678..82752 | - | 75 | Protein_75 | endonuclease | - |
| G5V60_RS24720 () | 82998..83210 | - | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| G5V60_RS24725 () | 83346..83906 | - | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| G5V60_RS24730 () | 84009..84869 | - | 861 | WP_000704513.1 | putative protein YcjY | VF |
| G5V60_RS24735 () | 84928..85674 | - | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| G5V60_RS24740 () | 85694..90964 | - | 5271 | WP_000986963.1 | Multifunctional conjugation protein TraI | Relaxase |
| G5V60_RS24745 () | 91046..91273 | + | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| G5V60_RS24750 () | 91273..91671 | + | 399 | WP_000911313.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| G5V60_RS24755 () | 91680..93833 | - | 2154 | WP_000009324.1 | type IV conjugative transfer system coupling protein TraD | - |
| G5V60_RS24760 () | 94086..94817 | - | 732 | WP_023565183.1 | complement resistance protein TraT | - |
| G5V60_RS24765 () | 94849..95346 | - | 498 | WP_000605857.1 | entry exclusion protein | - |
| G5V60_RS24770 () | 95362..98184 | - | 2823 | WP_001007018.1 | conjugal transfer mating pair stabilization protein TraG | - |
| G5V60_RS24775 () | 98181..99554 | - | 1374 | WP_001517790.1 | conjugal transfer protein TraH | - |
| G5V60_RS24780 () | 99554..99967 | - | 414 | WP_001324104.1 | F-type conjugal transfer protein TrbF | - |
| G5V60_RS24785 () | 99921..100262 | - | 342 | WP_001443031.1 | P-type conjugative transfer protein TrbJ | - |
| G5V60_RS24790 () | 100192..100737 | - | 546 | WP_000059851.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| G5V60_RS24795 () | 100724..101008 | - | 285 | WP_000624109.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| G5V60_RS24800 () | 101089..101403 | + | 315 | WP_001324103.1 | hypothetical protein | - |
| G5V60_RS24805 () | 101405..101752 | - | 348 | WP_001287910.1 | conjugal transfer protein TrbA | - |
| G5V60_RS24810 () | 101768..102511 | - | 744 | WP_001030377.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| G5V60_RS24815 () | 102504..102761 | - | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| G5V60_RS24820 () | 102788..104596 | - | 1809 | WP_000821838.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| G5V60_RS24825 () | 104593..105231 | - | 639 | WP_000777695.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| G5V60_RS24830 () | 105240..106232 | - | 993 | WP_000830183.1 | conjugal transfer pilus assembly protein TraU | - |
| G5V60_RS24835 () | 106229..106861 | - | 633 | WP_001203717.1 | type-F conjugative transfer system protein TraW | - |
| G5V60_RS24840 () | 106858..107244 | - | 387 | WP_000099691.1 | type-F conjugative transfer system protein TrbI | - |
| G5V60_RS24845 () | 107241..109868 | - | 2628 | WP_001064245.1 | type IV secretion system protein TraC | - |
| G5V60_RS24850 () | 110028..110249 | - | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| G5V60_RS24855 () | 110384..110899 | - | 516 | WP_000809838.1 | type IV conjugative transfer system lipoprotein TraV | - |
| G5V60_RS24860 () | 110896..111147 | - | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| G5V60_RS24865 () | 111159..111389 | - | 231 | WP_001442573.1 | conjugal transfer protein TrbD | - |
| G5V60_RS24870 () | 111343..111933 | - | 591 | WP_000002787.1 | conjugal transfer protein TraP | - |
| G5V60_RS24875 () | 111923..113350 | - | 1428 | WP_000146684.1 | conjugal transfer protein TraB | - |
| G5V60_RS24880 () | 113350..114054 | - | 705 | WP_148713163.1 | type-F conjugative transfer system secretin TraK | - |
| G5V60_RS24885 () | 114065..114631 | - | 567 | WP_000399790.1 | type IV conjugative transfer system protein TraE | - |
| G5V60_RS24890 () | 114653..114964 | - | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| G5V60_RS24895 () | 114979..115344 | - | 366 | WP_000340282.1 | type IV conjugative transfer system pilin TraA | - |
| G5V60_RS24900 () | 115387..115602 | - | 216 | WP_001352842.1 | conjugal transfer relaxosome protein TraY | - |
| G5V60_RS24905 () | 115738..116385 | - | 648 | WP_000332520.1 | conjugal transfer transcriptional regulator TraJ | - |
| G5V60_RS24910 () | 116577..116960 | - | 384 | WP_001063020.1 | relaxosome protein TraM | - |
| G5V60_RS24915 () | 117312..117902 | + | 591 | WP_166494936.1 | hypothetical protein | VF |
| G5V60_RS24920 () | 118197..119018 | - | 822 | WP_001234475.1 | DUF945 domain-containing protein | - |
| G5V60_RS24925 () | 119137..119424 | - | 288 | WP_000107546.1 | hypothetical protein | - |
| G5V60_RS25760 () | 119449..119655 | - | 207 | WP_000547965.1 | hypothetical protein | - |
| G5V60_RS24935 () | 119725..120084 | + | 360 | Protein_119 | hypothetical protein | - |
| G5V60_RS24940 () | 120322..120480 | - | 159 | WP_001302184.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| - () | 120545..120743 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 120545..120743 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 120545..120743 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| - () | 120545..120743 | - | 199 | NuclAT_0 | - | Antitoxin Detail |
| G5V60_RS24945 () | 120755..121474 | - | 720 | WP_000116348.1 | plasmid SOS inhibition protein A | - |
| G5V60_RS24950 () | 121471..121905 | - | 435 | WP_000845928.1 | conjugation system SOS inhibitor PsiB | - |
| G5V60_RS24955 () | 121960..123918 | - | 1959 | WP_029487628.1 | ParB/RepB/Spo0J family partition protein | - |
| G5V60_RS24960 () | 123984..124217 | - | 234 | WP_000005990.1 | DUF905 family protein | - |
| G5V60_RS24965 () | 124274..124813 | - | 540 | WP_000290801.1 | single-stranded DNA-binding protein | - |
| G5V60_RS24970 () | 125131..125640 | + | 510 | WP_071600123.1 | hypothetical protein | - |
| G5V60_RS24975 () | 125610..125801 | - | 192 | WP_001027495.1 | hypothetical protein | - |
| G5V60_RS24980 () | 125798..126220 | - | 423 | WP_000271685.1 | DUF1380 family protein | - |
| G5V60_RS24985 () | 126267..126569 | - | 303 | WP_072148062.1 | antirestriction protein | - |
| G5V60_RS25765 () | 127105..127881 | - | 777 | WP_001005035.1 | hypothetical protein | - |
| G5V60_RS25000 () | 127927..128481 | - | 555 | WP_077248347.1 | DUF1380 family protein | - |
| G5V60_RS25005 () | 128375..128596 | - | 222 | WP_001104870.1 | hypothetical protein | - |
| G5V60_RS25010 () | 128597..129280 | - | 684 | WP_000085939.1 | DNA methylase | - |
| G5V60_RS25015 () | 129357..129662 | - | 306 | WP_010891292.1 | hypothetical protein | - |
| G5V60_RS25770 () | 129666..130567 | - | 902 | Protein_135 | DUF1281 domain-containing protein | - |
| G5V60_RS25030 () | 131305..132276 | - | 972 | WP_000817035.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| G5V60_RS25035 () | 132276..133442 | - | 1167 | WP_000772446.1 | Sporulation initiation inhibitor protein Soj | VF |
| G5V60_RS25040 () | 134030..134785 | - | 756 | WP_000852146.1 | replication initiation protein RepE | - |
| G5V60_RS25045 () | 135537..136343 | - | 807 | WP_000016982.1 | site-specific integrase | - |
| G5V60_RS25050 () | 136344..136649 | - | 306 | WP_001159868.1 | type II toxin-antitoxin system toxin CcdB | Toxin Detail |
| G5V60_RS25055 () | 136651..136869 | - | 219 | WP_000813634.1 | type II toxin-antitoxin system antitoxin CcdA | Antitoxin Detail |
| G5V60_RS25060 () | 137437..137949 | + | 513 | WP_000151784.1 | hypothetical protein | - |
| G5V60_RS25065 () | 137983..139116 | - | 1134 | WP_000545984.1 | DUF3800 domain-containing protein | - |
| G5V60_RS25070 () | 139283..140056 | - | 774 | WP_000905949.1 | hypothetical protein | - |
| G5V60_RS25075 () | 140069..140569 | - | 501 | WP_000528932.1 | hypothetical protein | - |
| G5V60_RS25080 () | 140834..141064 | + | 231 | WP_001261278.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| G5V60_RS25085 () | 141061..141477 | + | 417 | WP_001034046.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| G5V60_RS25090 () | 141522..145316 | - | 3795 | WP_001144731.1 | hypothetical protein | - |
| G5V60_RS25095 () | 145697..145927 | + | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| G5V60_RS25100 () | 145924..146340 | + | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| G5V60_RS25105 () | 146415..147980 | + | 1566 | WP_001128474.1 | AAA family ATPase | - |
| G5V60_RS25110 () | 147965..148987 | + | 1023 | WP_000361402.1 | helicase UvrD | - |
| G5V60_RS25115 () | 149241..149938 | - | 698 | Protein_153 | IS1 family transposase IS1S | Transposase |
| G5V60_RS25120 () | 150318..152519 | - | 2202 | WP_000973519.1 | Ferric aerobactin receptor | VF |
| G5V60_RS25125 () | 152601..153878 | - | 1278 | WP_000750130.1 | L-lysine N6-monooxygenase | VF |
| G5V60_RS25130 () | 153875..155617 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| G5V60_RS25135 () | 155617..156564 | - | 948 | WP_000011908.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| G5V60_RS25140 () | 156565..158289 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| G5V60_RS25145 () | 158425..159618 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| G5V60_RS25150 () | 159998..160378 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| G5V60_RS25155 () | 160719..161132 | - | 414 | Protein_161 | phosphopyruvate hydratase | - |
| G5V60_RS25160 () | 161621..162478 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| G5V60_RS25165 () | 162475..163332 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| G5V60_RS25170 () | 163329..164156 | - | 828 | WP_000983710.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| G5V60_RS25175 () | 164156..165070 | - | 915 | WP_164699456.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| G5V60_RS25180 () | 165426..166123 | + | 698 | Protein_166 | IS1 family transposase IS1S | Transposase |
| G5V60_RS25185 () | 166303..166816 | - | 514 | Protein_167 | DUF4113 domain-containing protein | - |
| G5V60_RS25775 () | 166877..166981 | - | 105 | Protein_168 | AAA family ATPase | - |
| G5V60_RS25190 () | 166983..167306 | - | 324 | Protein_169 | IS21 family transposase IS21 | Transposase |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|