MGE detailed information
MGE type: Conjugative plasmid MGE length: 174241 bp
Accession: NC_009837 Location: 1..174241 Organism: Escherichia coli APEC O1 Replicon: plasmid pAPEC-O1-ColBM
Accession: NC_009837 Location: 1..174241 Organism: Escherichia coli APEC O1 Replicon: plasmid pAPEC-O1-ColBM
Gene structure
The 5 kb flanking regions of this MGE are displayed.
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| APECO1_RS25700 () | 56..753 | + | 698 | Protein_0 | IS1 family transposase IS1S | Transposase |
| APECO1_RS25705 () | 1053..2219 | + | 1167 | WP_001238646.1 | Sporulation initiation inhibitor protein Soj | VF |
| APECO1_RS25710 () | 2219..3190 | + | 972 | WP_000817028.1 | ParB/RepB/Spo0J family plasmid partition protein | - |
| APECO1_RS25720 () | 4146..5258 | - | 1113 | WP_021513474.1 | IS4 family transposase IS421 | Transposase |
| APECO1_RS25725 () | 5524..5826 | + | 303 | WP_072256028.1 | antirestriction protein | - |
| APECO1_RS25730 () | 5890..6288 | + | 399 | WP_026020284.1 | DUF1380 family protein | - |
| APECO1_RS25735 () | 6288..6470 | + | 183 | WP_001027505.1 | hypothetical protein | - |
| APECO1_RS31750 () | 6458..6786 | - | 329 | Protein_7 | pilus assembly protein | - |
| APECO1_RS25745 () | 7464..7694 | + | 231 | WP_000218642.1 | hypothetical protein | - |
| APECO1_RS25750 () | 7746..9107 | + | 1362 | WP_000170649.1 | DUF3560 domain-containing protein | - |
| APECO1_RS25755 () | 9155..9718 | + | 564 | WP_001332335.1 | class I SAM-dependent methyltransferase | - |
| APECO1_RS30710 () | 9870..10136 | + | 267 | WP_072254135.1 | hypothetical protein | - |
| APECO1_RS25765 () | 10609..11136 | + | 528 | WP_000290793.1 | single-stranded DNA-binding protein | - |
| APECO1_RS25770 () | 11192..11425 | + | 234 | WP_000006004.1 | DUF905 domain-containing protein | - |
| APECO1_RS25775 () | 11484..13442 | + | 1959 | WP_001145470.1 | ParB/RepB/Spo0J family partition protein | - |
| APECO1_RS25780 () | 13497..13931 | + | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
| APECO1_RS25785 () | 13928..14647 | + | 720 | WP_001276228.1 | plasmid SOS inhibition protein A | - |
| APECO1_RS31660 () | 14659..14847 | - | 189 | WP_001299721.1 | hypothetical protein | - |
| - () | 14659..14883 | + | 225 | NuclAT_0 | - | - |
| - () | 14659..14883 | + | 225 | NuclAT_0 | - | - |
| - () | 14659..14883 | + | 225 | NuclAT_0 | - | - |
| - () | 14659..14883 | + | 225 | NuclAT_0 | - | - |
| APECO1_RS25795 () | 14927..15085 | + | 159 | WP_001312861.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| APECO1_RS30720 () | 15776..15982 | + | 207 | WP_000547939.1 | hypothetical protein | - |
| APECO1_RS25805 () | 16007..16294 | + | 288 | WP_000107535.1 | hypothetical protein | - |
| APECO1_RS25810 () | 16415..17236 | + | 822 | WP_001234469.1 | DUF945 domain-containing protein | - |
| APECO1_RS25815 () | 17533..18135 | - | 603 | WP_000243709.1 | hypothetical protein | VF |
| APECO1_RS25820 () | 18456..18839 | + | 384 | WP_001151524.1 | relaxosome protein TraM | - |
| APECO1_RS25825 () | 19026..19715 | + | 690 | WP_000283385.1 | conjugal transfer transcriptional regulator TraJ | - |
| APECO1_RS25830 () | 19814..20209 | + | 396 | WP_024179280.1 | conjugal transfer relaxosome protein TraY | - |
| APECO1_RS25835 () | 20242..20607 | + | 366 | WP_000994779.1 | type IV conjugative transfer system pilin TraA | - |
| APECO1_RS25840 () | 20622..20933 | + | 312 | WP_000012106.1 | type IV conjugative transfer system protein TraL | - |
| APECO1_RS25845 () | 20955..21521 | + | 567 | WP_000399792.1 | type IV conjugative transfer system protein TraE | - |
| APECO1_RS25850 () | 21532..22236 | + | 705 | WP_072095570.1 | type-F conjugative transfer system secretin TraK | - |
| APECO1_RS25855 () | 22236..23663 | + | 1428 | WP_000146692.1 | conjugal transfer protein TraB | - |
| APECO1_RS25860 () | 23653..24243 | + | 591 | WP_000002792.1 | conjugal transfer protein TraP | - |
| APECO1_RS25865 () | 24197..24427 | + | 231 | WP_001352845.1 | conjugal transfer protein TrbD | - |
| APECO1_RS25870 () | 24439..24690 | + | 252 | WP_001038342.1 | conjugal transfer protein TrbG | - |
| APECO1_RS25875 () | 24687..25202 | + | 516 | WP_000809841.1 | type IV conjugative transfer system lipoprotein TraV | - |
| APECO1_RS29740 () | 25337..25558 | + | 222 | WP_001278689.1 | conjugal transfer protein TraR | - |
| APECO1_RS25885 () | 25718..28345 | + | 2628 | WP_001064247.1 | type IV secretion system protein TraC | - |
| APECO1_RS25890 () | 28342..28728 | + | 387 | WP_000097319.1 | type-F conjugative transfer system protein TrbI | - |
| APECO1_RS25895 () | 28725..29357 | + | 633 | WP_001203720.1 | type-F conjugative transfer system protein TraW | - |
| APECO1_RS25900 () | 29354..30346 | + | 993 | WP_000830187.1 | conjugal transfer pilus assembly protein TraU | - |
| APECO1_RS25905 () | 30355..30993 | + | 639 | WP_000777688.1 | type-F conjugative transfer system pilin assembly protein TrbC | - |
| APECO1_RS25910 () | 30990..32798 | + | 1809 | WP_000821847.1 | type-F conjugative transfer system mating-pair stabilization protein TraN | - |
| APECO1_RS25915 () | 32825..33082 | + | 258 | WP_000864318.1 | conjugal transfer protein TrbE | - |
| APECO1_RS25920 () | 33075..33818 | + | 744 | WP_001030367.1 | type-F conjugative transfer system pilin assembly protein TraF | - |
| APECO1_RS25925 () | 33834..34181 | + | 348 | WP_001287911.1 | conjugal transfer protein TrbA | - |
| APECO1_RS25930 () | 34183..34458 | - | 276 | WP_001513501.1 | hypothetical protein | - |
| APECO1_RS25935 () | 34584..34820 | + | 237 | WP_000270010.1 | type-F conjugative transfer system pilin chaperone TraQ | - |
| APECO1_RS25940 () | 34807..35352 | + | 546 | WP_000059833.1 | type-F conjugative transfer system pilin assembly thiol-disulfide isomerase TrbB | - |
| APECO1_RS29745 () | 35282..35623 | + | 342 | WP_001442101.1 | P-type conjugative transfer protein TrbJ | - |
| APECO1_RS29755 () | 35989..37363 | + | 1375 | Protein_49 | conjugal transfer protein TraH | - |
| APECO1_RS25950 () | 37360..40185 | + | 2826 | WP_001007037.1 | conjugal transfer mating pair stabilization protein TraG | - |
| APECO1_RS25955 () | 40182..40691 | + | 510 | WP_000628107.1 | conjugal transfer entry exclusion protein TraS | - |
| APECO1_RS25960 () | 40705..41436 | + | 732 | WP_000850422.1 | complement resistance protein TraT | - |
| APECO1_RS25965 () | 41689..43842 | + | 2154 | WP_000009325.1 | type IV conjugative transfer system coupling protein TraD | - |
| APECO1_RS25970 () | 43851..44249 | - | 399 | WP_000911333.1 | tRNA(fMet)-specific endonuclease VapC | Toxin Detail |
| APECO1_RS25975 () | 44249..44476 | - | 228 | WP_000450520.1 | toxin-antitoxin system antitoxin VapB | Antitoxin Detail |
| APECO1_RS25980 () | 44558..49828 | + | 5271 | WP_000986968.1 | Multifunctional conjugation protein TraI | Relaxase |
| APECO1_RS25985 () | 49848..50594 | + | 747 | WP_000205749.1 | conjugal transfer pilus acetylase TraX | - |
| APECO1_RS25990 () | 50653..51513 | + | 861 | WP_000704513.1 | putative protein YcjY | VF |
| APECO1_RS25995 () | 51616..52176 | + | 561 | WP_000139315.1 | fertility inhibition protein FinO | - |
| APECO1_RS26000 () | 52312..52524 | + | 213 | WP_001299730.1 | ANR family transcriptional regulator | - |
| APECO1_RS31665 () | 52770..52844 | + | 75 | Protein_61 | endonuclease | - |
| - () | 53100..53161 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 53100..53161 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 53100..53161 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| - () | 53100..53161 | - | 62 | NuclAT_1 | - | Antitoxin Detail |
| APECO1_RS26005 () | 53148..53354 | + | 207 | WP_001351576.1 | type I toxin-antitoxin system Hok family toxin | Toxin Detail |
| APECO1_RS26010 () | 53638..53895 | + | 258 | WP_000083845.1 | replication regulatory protein RepA | - |
| APECO1_RS26015 () | 54127..54201 | + | 75 | WP_001442103.1 | RepA leader peptide Tap | - |
| APECO1_RS26020 () | 54194..54676 | + | 483 | WP_001273588.1 | hypothetical protein | - |
| APECO1_RS26025 () | 54669..55526 | + | 858 | WP_000774297.1 | incFII family plasmid replication initiator RepA | - |
| APECO1_RS26030 () | 56489..56740 | + | 252 | WP_001132900.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin Detail |
| APECO1_RS26035 () | 56737..57024 | + | 288 | WP_000222767.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| APECO1_RS26050 () | 58775..62908 | + | 4134 | WP_001080138.1 | Hemoglobin-binding protease hbp autotransporter | VF |
| APECO1_RS26060 () | 63020..63702 | + | 683 | Protein_71 | IS1-like element IS1A family transposase | - |
| APECO1_RS26065 () | 63773..64519 | - | 747 | WP_001016257.1 | IS21 family transposase ISEc12 | Transposase |
| APECO1_RS26070 () | 64534..66075 | - | 1542 | WP_001298859.1 | IS21 family transposase ISEc12 | Transposase |
| APECO1_RS26075 () | 66313..67350 | - | 1038 | WP_000361403.1 | hypothetical protein | - |
| APECO1_RS26080 () | 67335..68900 | - | 1566 | WP_001128474.1 | AAA family ATPase | - |
| APECO1_RS26085 () | 68975..69391 | - | 417 | WP_001034044.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| APECO1_RS26090 () | 69388..69618 | - | 231 | WP_001261286.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| APECO1_RS26095 () | 69980..70432 | + | 453 | WP_000670960.1 | N-acetyltransferase | - |
| APECO1_RS26100 () | 70464..71996 | - | 1533 | WP_001017349.1 | NAD(P)-binding domain-containing protein | - |
| APECO1_RS26105 () | 71993..72262 | - | 270 | WP_000379710.1 | SemiSWEET transporter | - |
| APECO1_RS26110 () | 72264..73280 | - | 1017 | WP_000583428.1 | Gfo/Idh/MocA family oxidoreductase | - |
| APECO1_RS26115 () | 73283..74110 | - | 828 | WP_000154003.1 | HAD-IIB family hydrolase | - |
| APECO1_RS26120 () | 74094..75332 | - | 1239 | WP_012006540.1 | 3-oxo-glucose-6-phosphate:glutamate aminotransferase | VF |
| APECO1_RS26125 () | 75872..77005 | + | 1134 | WP_000545983.1 | DUF3800 domain-containing protein | - |
| APECO1_RS26130 () | 77025..77309 | + | 285 | WP_000642771.1 | hypothetical protein | - |
| APECO1_RS26135 () | 77306..77503 | - | 198 | WP_000215657.1 | hypothetical protein | - |
| APECO1_RS26140 () | 78087..78476 | + | 390 | WP_001282151.1 | IS66 family transposase ISEc8 | Transposase |
| APECO1_RS26145 () | 78473..78820 | + | 348 | WP_000612591.1 | IS66 family transposase ISEc8 | Transposase |
| APECO1_RS26150 () | 78870..80408 | + | 1539 | WP_000997962.1 | IS66 family transposase ISEc8 | Transposase |
| APECO1_RS26160 () | 80434..81665 | + | 1232 | WP_094284489.1 | IS3 family transposase IS2 | Transposase |
| APECO1_RS26165 () | 81930..85427 | + | 3498 | WP_001038844.1 | Outer membrane protein IcsA autotransporter | VF |
| APECO1_RS26175 () | 85574..86767 | + | 1194 | Protein_92 | IS3 family transposase IS629 | Transposase |
| APECO1_RS26180 () | 86860..88047 | - | 1188 | WP_160348040.1 | MFS transporter | - |
| APECO1_RS26185 () | 88104..88865 | - | 762 | WP_000020503.1 | Fe(3+) dicitrate transport ATP-binding protein FecE | VF |
| APECO1_RS26190 () | 88865..89902 | - | 1038 | WP_000110580.1 | Hemin transport system permease protein HmuU | VF |
| APECO1_RS26195 () | 89902..90900 | - | 999 | WP_000756335.1 | ABC transporter substrate-binding protein | - |
| APECO1_RS28010 () | 91050..91208 | - | 159 | Protein_97 | integrase core domain-containing protein | - |
| APECO1_RS26200 () | 91255..91845 | - | 591 | WP_000086535.1 | Tn3 family transposase TnpR_ISSba14 | Transposase |
| APECO1_RS26205 () | 92346..92630 | + | 285 | WP_012006537.1 | ribbon-helix-helix domain-containing protein | Antitoxin Detail |
| APECO1_RS26210 () | 92630..92905 | + | 276 | WP_000421266.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| APECO1_RS26215 () | 93011..93250 | + | 240 | WP_001105068.1 | hypothetical protein | - |
| APECO1_RS26230 () | 94942..97080 | + | 2139 | WP_000350635.1 | AAA family ATPase | - |
| APECO1_RS26235 () | 97242..97658 | - | 417 | WP_001044768.1 | type II toxin-antitoxin system VapC family toxin | Toxin Detail |
| APECO1_RS26240 () | 97655..97885 | - | 231 | WP_001261287.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | Antitoxin Detail |
| APECO1_RS26245 () | 98447..98797 | + | 351 | WP_000493379.1 | hypothetical protein | - |
| APECO1_RS26250 () | 98841..99530 | + | 690 | WP_000796229.1 | hypothetical protein | - |
| APECO1_RS26255 () | 99527..100318 | + | 792 | WP_000016494.1 | site-specific integrase | - |
| APECO1_RS26260 () | 100496..100849 | + | 354 | WP_000864812.1 | colicin M immunity protein | - |
| APECO1_RS26265 () | 100899..101714 | - | 816 | WP_001312845.1 | lipid II-degrading bacteriocin colicin M | - |
| APECO1_RS26270 () | 101958..102485 | + | 528 | WP_000203272.1 | colicin B immunity protein | - |
| APECO1_RS29825 () | 102503..102670 | - | 168 | Protein_112 | colicin-B | - |
| APECO1_RS26275 () | 102843..103124 | + | 282 | WP_001105066.1 | hypothetical protein | - |
| APECO1_RS31670 () | 103670..104656 | - | 987 | Protein_114 | IS4 family transposase IS421 | Transposase |
| APECO1_RS31675 () | 104657..105241 | - | 585 | Protein_115 | IS4 family transposase IS421 | Transposase |
| APECO1_RS26290 () | 105216..106490 | - | 1275 | WP_000489607.1 | HlyD family secretion protein | - |
| APECO1_RS26310 () | 108437..108706 | + | 270 | WP_000079941.1 | hypothetical protein | Antitoxin Detail |
| APECO1_RS26315 () | 108703..108984 | + | 282 | WP_000969982.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin Detail |
| APECO1_RS26320 () | 109030..109878 | + | 849 | WP_001058005.1 | 3'-5' exonuclease | - |
| APECO1_RS26325 () | 109995..110477 | + | 483 | WP_001311056.1 | hypothetical protein | - |
| APECO1_RS26330 () | 110779..111126 | + | 348 | WP_000142437.1 | hypothetical protein | - |
| APECO1_RS26340 () | 111685..112720 | + | 1036 | Protein_123 | 3-deoxy-7-phosphoheptulonate synthase | - |
| APECO1_RS26350 () | 113575..115752 | + | 2178 | WP_001222186.1 | Ferric enterobactin receptor | VF |
| APECO1_RS26355 () | 115797..116753 | - | 957 | WP_000271276.1 | Ferri-bacillibactin esterase BesA | VF |
| APECO1_RS26360 () | 116838..118067 | - | 1230 | WP_000933675.1 | Enterochelin esterase | VF |
| APECO1_RS26365 () | 118171..121830 | - | 3660 | WP_001111199.1 | Multidrug efflux ATP-binding/permease protein | VF |
| APECO1_RS26370 () | 121970..123085 | - | 1116 | WP_001318220.1 | Elloramycin glycosyltransferase ElmGT | VF |
| APECO1_RS30755 () | 124321..125426 | - | 1106 | Protein_129 | IS481 family transposase ISKpn28 | Transposase |
| APECO1_RS29870 () | 125980..126179 | + | 200 | Protein_130 | lysis protein | - |
| APECO1_RS26395 () | 126237..126530 | - | 294 | WP_000738422.1 | increased serum survival lipoprotein Iss | - |
| APECO1_RS26410 () | 127157..128385 | + | 1229 | WP_088130945.1 | IS3 family transposase IS2 | Transposase |
| APECO1_RS26420 () | 129609..130802 | + | 1194 | WP_000450495.1 | GTP-binding protein | - |
| APECO1_RS31440 () | 130980..131129 | + | 150 | Protein_134 | IS3 family transposase IS2 | Transposase |
| APECO1_RS29895 () | 131439..132828 | + | 1390 | Protein_135 | ISNCY family transposase ISKpn21 | Transposase |
| APECO1_RS26440 () | 133063..134004 | + | 942 | WP_000974762.1 | hypothetical protein | - |
| APECO1_RS29905 () | 134133..134327 | - | 195 | Protein_137 | IS200/IS605-like element IS200C family transposase | - |
| APECO1_RS26445 () | 134716..135413 | - | 698 | Protein_138 | IS1 family transposase IS1S | Transposase |
| APECO1_RS26455 () | 135510..135701 | - | 192 | WP_000925960.1 | hypothetical protein | - |
| APECO1_RS26460 () | 135927..137429 | - | 1503 | WP_000715078.1 | hypothetical protein | - |
| APECO1_RS26470 () | 138064..138513 | - | 450 | WP_000238252.1 | hypothetical protein | - |
| APECO1_RS26475 () | 138631..139110 | + | 480 | WP_000190054.1 | hypothetical protein | - |
| APECO1_RS26480 () | 139550..140212 | + | 663 | WP_000163251.1 | hypothetical protein | - |
| APECO1_RS26485 () | 140223..140920 | - | 698 | Protein_144 | IS1 family transposase | - |
| APECO1_RS26490 () | 141445..143646 | - | 2202 | WP_000973517.1 | Ferric aerobactin receptor | VF |
| APECO1_RS26495 () | 143728..145005 | - | 1278 | WP_012006523.1 | L-lysine N6-monooxygenase | VF |
| APECO1_RS26500 () | 145002..146744 | - | 1743 | WP_001015721.1 | Aerobactin synthase | VF |
| APECO1_RS26505 () | 146744..147691 | - | 948 | WP_000011907.1 | N(6)-hydroxylysine O-acetyltransferase | VF |
| APECO1_RS26510 () | 147692..149416 | - | 1725 | WP_000602863.1 | N(2)-citryl-N(6)-acetyl-N(6)-hydroxylysine synthase | VF |
| APECO1_RS26515 () | 149552..150745 | + | 1194 | WP_000095526.1 | MFS transporter | - |
| APECO1_RS26520 () | 151126..151506 | - | 381 | WP_001318207.1 | fluoride efflux transporter CrcB | - |
| APECO1_RS26530 () | 151847..152260 | - | 414 | Protein_152 | phosphopyruvate hydratase | - |
| APECO1_RS30775 () | 152258..152515 | + | 258 | Protein_153 | Tn3 family transposase | - |
| APECO1_RS26535 () | 152749..153606 | - | 858 | WP_000968139.1 | Manganese transport system membrane protein MntB | ARG |
| APECO1_RS26540 () | 153603..154460 | - | 858 | WP_001101723.1 | Manganese transport system membrane protein MntB | ARG |
| APECO1_RS26545 () | 154457..155284 | - | 828 | WP_000983712.1 | Iron(3+)-hydroxamate import ATP-binding protein FhuC | VF |
| APECO1_RS26550 () | 155284..156198 | - | 915 | WP_000949004.1 | Putative metal ABC transporter substrate-binding protein Hpf | VF |
| APECO1_RS26555 () | 156554..157251 | + | 698 | Protein_158 | IS1 family transposase IS1S | Transposase |
| APECO1_RS26560 () | 157431..157944 | - | 514 | Protein_159 | DUF4113 domain-containing protein | - |
| APECO1_RS31445 () | 158005..158109 | - | 105 | Protein_160 | AAA family ATPase | - |
| APECO1_RS26565 () | 158111..158434 | - | 324 | Protein_161 | IS21 family transposase IS21 | Transposase |
| APECO1_RS26580 () | 159180..160157 | + | 978 | WP_000361611.1 | RepB family plasmid replication initiator protein | - |
| APECO1_RS26585 () | 160442..161182 | - | 741 | WP_001066954.1 | tyrosine-type recombinase/integrase | - |
| APECO1_RS26590 () | 161303..161491 | - | 189 | WP_014640565.1 | hypothetical protein | - |
| APECO1_RS26595 () | 161865..162767 | - | 903 | WP_001312822.1 | hypothetical protein | VF |
| APECO1_RS26600 () | 162836..163945 | - | 1110 | WP_000771475.1 | SDR family oxidoreductase | - |
| APECO1_RS26610 () | 164378..165277 | - | 900 | WP_049825659.1 | Protease 7 | VF |
| APECO1_RS29950 () | 166606..166764 | - | 159 | WP_001312823.1 | integrase core domain-containing protein | - |
| APECO1_RS26630 () | 166967..168180 | + | 1214 | WP_162842477.1 | IS3 family transposase IS629 | Transposase |
| APECO1_RS26635 () | 168328..168653 | - | 326 | Protein_170 | IS3 family transposase ISLad1 | Transposase |
| APECO1_RS26640 () | 169634..170821 | + | 1188 | WP_000928803.1 | efflux RND transporter periplasmic adaptor subunit | - |
| APECO1_RS26645 () | 170818..172758 | + | 1941 | WP_000733250.1 | Macrolide export ATP-binding/permease protein MacB | VF |
| APECO1_RS26650 () | 172762..174132 | + | 1371 | WP_001312828.1 | efflux transporter outer membrane subunit | - |
Similar MGE(s)
Similar MGE(s) is defined as other TA-related MGE(s) with Mash distance < 0.01 to this MGE.
| Detail | Organism | MGE type | Related TA | Genome accession | Coordinates | Mash distance |
|---|