SecReT6, T6SS database

Detailed information of component protein

Summary

Component ID	T6CP010955
Component protein type	TssL
T6SS ID (Type)	T6SS00802 (Type Unknown)
Strain	Vibrio anguillarum NB10
Replicon	chromosome
Sequence	Protein sequence (381 a.a.); Nucleotide sequence (1143 bp)
Reference	[1] Weber B, Hasic M, Chen C, et al. Type VI secretion modulates quorum sensing and stress response in Vibrio anguillarum. Environ Microbiol. 2009 Dec;11(12):3018-28. doi: 10.1111/j.1462-2920.2009.02005.x. Epub 2009 Jul 14. PMID: 19624706 [2] Weber B, Lindell K, El Qaidi S, et al. The phosphotransferase VanU represses expression of four qrr genes antagonizing VanO-mediated quorum-sensing regulation in Vibrio anguillarum. Microbiology (Reading). 2011 Dec;157(Pt 12):3324-3339. doi: 10.1099/mic.0.051011-0. Epub 2011 Sep 21. PMID: 21948044

Experimental investigation has been performed on this T6SS

External database links

Locus tag (Gene)	-
Coordinate (Strand)	8693..9835 (+)
NCBI ID	-
GenBank	GQ118992
Uniprot ID	-
KEGG ID	-
PDB ID	-

Pfam domain hit(s)

Domain	Pfam ID	E-value	Aligned region
DotU	PF09850.11	2.3e-42	50..249

Transmembrane helices

Transmembrane helices are predicted using TMHMM 2.0 software.

Prediction	Region	Sequence
Outside	1-380	MGGLFNEEPTVQIRRVTSTESAHKQHLLPPKADTSGTERLIEDLAIYGSPLLNAATELLGILVTIKRQGTPRDINRFRQKLLYAIDAFRLRGLHLDYHPSVIEKSCFVLCAAFDEAVLYTAWGERARWENHSLLSKVFSQRDGGEAFFVLLDKASQQPNKLVDFIELQYVLLALGFKGRFRHEDESQLHDITARAYGLIRHYRSESPFPVPQTPTLIEGKRPWLMISMGKTLGLACLVLASGYGFTEYWYNSRVQPLLAQFSAIDMSDVNLKKNSSDLVYLSSDADLGRQSESLEEETGMKGKVVTQQWEIILAVFSRASDALRLSTELKQAGYESFTREMEHGVELYLHAGDDLNTIRKLKNELNVRFGLNATIKRALK

Signal peptides

Signal peptides and corresponding cleavage sites are predicted using SignalP 5.0 software.

Sec/SPI: "standard" secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I (Lep).

Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase II (Lsp).

Tat/SPI: Tat signal peptides transported by the Tat translocon and cleaved by Signal Peptidase I (Lep).

Prediction	Probability	Cleavage site	Signal peptide sequence
Other	0.9923	-	-

Protein sequence: 381 a.a.

						>T6CP010955 GQ118992:8693-9835 [Vibrio anguillarum] [TssL]
MGGLFNEEPTVQIRRVTSTESAHKQHLLPPKADTSGTERLIEDLAIYGSPLLNAATELLGILVTIKRQGTPRDINRFRQK
LLYAIDAFRLRGLHLDYHPSVIEKSCFVLCAAFDEAVLYTAWGERARWENHSLLSKVFSQRDGGEAFFVLLDKASQQPNK
LVDFIELQYVLLALGFKGRFRHEDESQLHDITARAYGLIRHYRSESPFPVPQTPTLIEGKRPWLMISMGKTLGLACLVLA
SGYGFTEYWYNSRVQPLLAQFSAIDMSDVNLKKNSSDLVYLSSDADLGRQSESLEEETGMKGKVVTQQWEIILAVFSRAS
DALRLSTELKQAGYESFTREMEHGVELYLHAGDDLNTIRKLKNELNVRFGLNATIKRALK*					

Nucleotide sequence: 1143 bp

						>T6CP010955 GQ118992:8693-9835 [Vibrio anguillarum] [TssL]
ATGGGCGGATTATTTAACGAAGAACCGACGGTTCAAATTCGACGAGTGACATCGACCGAATCAGCTCACAAGCAGCATCT
GTTGCCACCCAAAGCGGATACTTCAGGCACAGAGCGATTGATTGAGGATCTTGCCATTTATGGTAGCCCTTTATTGAATG
CCGCCACGGAACTGTTGGGTATTTTAGTGACGATTAAGCGTCAAGGCACACCGAGAGACATCAACCGTTTTCGTCAAAAA
CTTTTGTACGCCATTGATGCGTTTCGTTTGCGTGGTTTGCACTTGGATTACCACCCAAGCGTGATTGAAAAAAGCTGCTT
TGTGTTGTGCGCGGCATTTGATGAAGCTGTGCTGTACACCGCTTGGGGAGAGCGTGCTCGTTGGGAAAATCATTCGTTGT
TGAGCAAGGTGTTTTCACAGCGCGATGGCGGAGAGGCCTTTTTTGTGTTGCTAGATAAGGCCAGCCAGCAGCCGAATAAA
CTTGTTGATTTTATTGAGCTTCAGTACGTGCTTTTGGCTTTGGGTTTCAAAGGGCGCTTTCGCCATGAAGACGAGAGCCA
ATTGCATGATATTACCGCTCGTGCGTACGGTCTCATTCGCCACTATCGCAGTGAAAGTCCTTTTCCGGTACCGCAAACAC
CAACGCTAATCGAAGGTAAACGCCCGTGGCTAATGATCAGTATGGGCAAAACGTTAGGCTTGGCTTGTTTGGTTCTGGCA
TCCGGGTATGGTTTTACTGAATATTGGTACAACAGCCGCGTGCAGCCGTTGTTGGCACAGTTTAGCGCGATCGATATGTC
AGACGTCAACCTGAAGAAAAACAGCAGTGACTTAGTGTACTTAAGTTCCGATGCGGATTTGGGGCGACAGAGTGAAAGCC
TAGAGGAAGAAACTGGAATGAAAGGAAAAGTGGTCACTCAGCAATGGGAGATCATTCTCGCGGTATTTTCTCGGGCGAGC
GACGCACTTCGTTTATCGACAGAACTCAAACAGGCAGGCTATGAGTCTTTTACTCGTGAGATGGAACATGGCGTTGAGCT
TTATCTTCACGCAGGTGACGACTTAAACACCATTCGTAAGTTGAAAAATGAACTCAATGTTCGCTTTGGTTTGAACGCCA
CGATTAAAAGAGCGCTGAAATAA					