 T4SS ID | 31 |
| Strain | Bartonella quintana str. Toulouse |
| Replicon | chromosome [Browse all T4SS(s) in this replicon] |
| Accession | NC_005955 |
| Location | 1250432..1263005 |
| Name | VirB |
| Function | effector translocation |
| Classification | Type IVA; Type P |
 This T4SS has been mentioned in a genome sequencing report. | |
Information of structure: 
T4SS components |
| Component | VirB1 | VirB2 | VirB3 | VirB4 | VirB5 | VirB6 | VirB7 | VirB8 | VirB9 |
| Number | 0 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
| Component | VirB10 | VirB11 | VirD4 | ||||||
| Number | 1 | 1 | 1 |
The information of T4SS components from NC_005955 | ||||||
 | ||||||
| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | Component | |
| 1 | BQ10480 | 1245981..1246826 [-], 846 | 49474574 | hypothetical protein | ||
| 2 | BQ10500 | 1248573..1248896 [-], 324 | 49474575 | hypothetical protein | ||
| 3 | BQ10510 | 1249136..1249339 [-], 204 | 49474576 | hypothetical protein | ||
| 4 | BQ10520 | 1249340..1250083 [-], 744 | 49474577 | hypothetical protein | ||
| 5 | BQ10530 (virB2) | 1250432..1250746 [+], 315 | 49474578 | virB2 protein | VirB2 | |
| 6 | BQ10540 (virB3) | 1250747..1251058 [+], 312 | 49474579 | virB3 protein | VirB3 | |
| 7 | BQ10550 (virB4) | 1251064..1253418 [+], 2355 | 49474580 | virB4 protein | VirB4 | |
| 8 | BQ10560 | 1253415..1253861 [+], 447 | 49474581 | hypothetical protein | VirB5 | |
| 9 | BQ10570 (virB6) | 1253848..1254813 [+], 966 | 49474582 | virB6 protein | VirB6 | |
| 10 | BQ10580 | 1255047..1255361 [+], 315 | 49474583 | hypothetical protein | VirB7 | |
| 11 | BQ10590 (virB8) | 1255351..1256019 [+], 669 | 49474584 | virB8 protein | VirB8 | |
| 12 | BQ10600 (virB9) | 1256019..1256885 [+], 867 | 49474585 | virB9 protein | VirB9 | |
| 13 | BQ10610 (virB10) | 1256875..1258032 [+], 1158 | 49474586 | virB10 protein | VirB10 | |
| 14 | BQ10620 (virB11) | 1258029..1259099 [+], 1071 | 49474587 | virB11 protein | VirB11 | |
| 15 | BQ10640 (traG) | 1261086..1263005 [+], 1920 | 49474588 | conjugal transfer protein TraG | VirD4 | |
| 16 | BQ10650 | 1263630..1265231 [+], 1602 | 49474589 | cell filamentation protein | ||
| 17 | BQ10660 | 1265556..1267058 [+], 1503 | 49474590 | hypothetical protein | ||
 Genes in the 5-Kb flanking regions if available, or non-essential genes in the T4SS gene cluster if any. |
Download FASTA format files |
| Proteins Genes |
Effectors |
| BepC, BepE, BepF, BepF |
The information of protein effectors | ||||||
| # | Locus tag (Gene) | Coordinates [+/-], size (bp) | Protein GI | Product | * | |
| 1 | BQ10650 | 1263630..1265231 [+], 1602 | 49474589 | cell filamentation protein | BepC | |
| 2 | BQ10660 | 1265556..1267058 [+], 1503 | 49474590 | hypothetical protein | BepE | |
| 3 | BQ10670 | 1267412..1269157 [+], 1746 | 49474591 | hypothetical protein | BepF | |
| 4 | BQ10680 | 1269465..1271246 [+], 1782 | 49474592 | hypothetical protein | BepF | |
Download FASTA format files |
| Proteins Genes |
| # | Name | Image | Resource | Detail | Reference |
| 1 | VirB8 |  | PDB (4LSO) | Crystal structure of the soluble domain of a Type IV secretion system protein VirB8 from Bartonella quintana Toulouse. | (1) PubMed: 26646013 |
(1) Gillespie JJ et al. (2015). Structural Insight into How Bacteria Prevent Interference between Multiple Divergent Type IV Secretion Systems. MBio. 6(6):e01867-15. [PudMed:26646013] 
|
|
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886]
|
| (2) Alsmark CM; Frank AC; Karlberg EO; Legault BA; Ardell DH; Canback B; Eriksson AS; Naslund AK; Handley SA; Huvet M; La Scola B; Holmberg M; Andersson SG (2004). The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae. Proc Natl Acad Sci U S A. 101(26):9716-21. [PudMed:15210978] |
| This literature contains experimental investigation |