| Effector Protein ID: 49474589 |
 T4SS name [ID] | VirB [31] |
| Gene symbol | - |
| Locus tag | BQ10650 |
| Strain | Bartonella quintana str. Toulouse |
| Replicon | chromosome [GenBank: NC_005955] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1263630..1265231 [+] |
| Product | cell filamentation protein |
| Effector type | Protein |
| Descripton | BepC |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Homologous to BepC protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. |
| UniProt ID | Q6FYV8 |
| KEGG ID | bqu:BQ10650 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | Fic [PF02661], Evalue: 3.3e-15, Aligned region: 50..162 |
| Protein Sequence: 533 a.a. [Download] |
| >gi|49474589|ref|YP_032631.1| cell filamentation protein [Bartonella quintana str. Toulouse] MLEHNYFYKNSATLKNKHGIKNPRKLYERCAHETAREAVNFRLEPPPGKFDAAYLRTIHWCLFHNTFEWA GVTRDQPFTFEDGSTACMPAMRPKGYKVPFAVGSQIQRELKKLEQRLTAKNNLQGLSRQEFAANAAEVFT ALDHAHPFRKGNGRTQRMFMEKLGQAAGYKIDFSLITKERMTYASIEAMQHNNPEPMKDLFEDITHPQKS LLLKEFISQMRSARLDEINNHIVLAAKEGVTYDGIYKGSSAEGFVIEVEGGTFIVGHKDDLKPEQVKILQ NGDFISFQKNNVQNMRETLIPSEILAPLTNEILAERLVNHCGVESYRHEVECLSKIVYGNTQALSQMIET INIDPSLGEQFVDHIIQNPKSVGKLAGKKILGLRSPARKRAEETVSQLSDTLKSYADIAHQTMADIIEQH SKEQRRTARSVENPGKDLQNLFALFPEQQREALSHSPTLQQQLHRFSRQLQNRLSSEERRAIQENDCTRL SCLLGVSASKAKDIAQIVKHTKEAQCQMRTLKVCRSASMALTS |
| - |
| Nucleotide Sequence: 1602 bp [Download] |
| >gi|49473688|ref|NC_005955.1|:1263630-1265231 Bartonella quintana str. Toulouse, complete genome ATGTTAGAGCATAATTATTTTTATAAAAACAGCGCAACACTGAAGAATAAACATGGCATAAAAAACCCGC GAAAACTGTATGAACGCTGTGCTCATGAGACAGCCAGAGAGGCTGTAAATTTTCGCCTTGAACCGCCACC AGGGAAATTTGATGCCGCTTATCTAAGGACAATTCACTGGTGCCTTTTCCATAACACTTTTGAATGGGCC GGTGTTACCCGAGATCAGCCCTTTACATTTGAAGATGGCAGCACTGCATGTATGCCAGCTATGCGACCAA AAGGTTATAAGGTTCCTTTTGCTGTCGGTTCACAAATTCAAAGAGAGCTTAAAAAATTAGAACAAAGACT AACCGCGAAGAATAATTTACAAGGCTTATCGCGCCAAGAATTTGCTGCAAATGCTGCTGAAGTTTTTACA GCTCTCGACCACGCGCATCCTTTCAGAAAAGGCAATGGGCGCACACAACGAATGTTTATGGAAAAACTCG GACAAGCGGCAGGCTATAAGATTGATTTTTCTTTGATCACAAAAGAACGCATGACATATGCCAGCATTGA AGCAATGCAACATAACAATCCAGAACCCATGAAAGATCTTTTTGAGGATATCACTCACCCTCAAAAATCC CTTCTTTTAAAGGAATTTATCTCTCAGATGAGAAGCGCTAGACTTGATGAAATTAACAATCATATTGTTT TGGCAGCAAAAGAAGGTGTGACCTATGATGGCATTTATAAAGGTTCTTCAGCTGAAGGTTTTGTTATAGA AGTAGAAGGTGGCACTTTCATCGTCGGGCACAAAGATGATCTTAAGCCAGAGCAAGTGAAAATATTACAG AATGGTGATTTCATCTCCTTTCAGAAAAACAATGTTCAAAACATGAGAGAAACACTTATCCCAAGCGAGA TATTAGCGCCTCTCACCAATGAGATCCTTGCCGAAAGGCTCGTAAACCATTGTGGGGTTGAATCATACCG CCATGAAGTCGAGTGTTTATCAAAAATTGTTTATGGCAACACACAAGCATTAAGCCAAATGATTGAGACA ATCAACATAGATCCAAGTTTAGGCGAACAGTTTGTCGATCACATTATCCAAAATCCTAAATCAGTTGGTA AGCTTGCCGGGAAAAAAATCCTGGGTCTAAGAAGCCCAGCGCGCAAACGTGCGGAAGAAACTGTTTCACA GCTGAGTGACACACTTAAAAGTTATGCCGATATAGCACATCAGACCATGGCTGACATCATAGAGCAACAC TCAAAAGAACAAAGACGCACAGCGCGCTCTGTCGAAAATCCTGGGAAAGACTTGCAAAACCTTTTTGCCT TGTTCCCAGAACAACAAAGAGAAGCCTTGTCTCATTCCCCTACGCTGCAACAACAACTCCATCGTTTTTC GCGTCAATTGCAAAATCGTTTATCATCAGAGGAGCGTCGAGCCATACAAGAAAACGATTGCACAAGACTT TCTTGTCTGCTTGGTGTATCGGCAAGCAAAGCAAAAGACATTGCTCAAATTGTGAAGCATACCAAAGAGG CACAATGTCAGATGCGTACCCTTAAAGTCTGCCGCTCCGCATCGATGGCTCTGACCAGCTAA |
| Reference |
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] 
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| experimental literature |