SecReT4
Effector Protein ID: 49474589
T4SS name [ID]VirB [31]
Gene symbol-
Locus tagBQ10650
StrainBartonella quintana str. Toulouse
Repliconchromosome [GenBank: NC_005955] [Browse all T4SS(s) in this replicon]
Location [Strand]1263630..1265231 [+]
Productcell filamentation protein
Effector typeProtein
DescriptonBepC
T4CP requirementT4CP Depedent
Target/EffectionHomologous to BepC protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells.
UniProt IDQ6FYV8
KEGG IDbqu:BQ10650
PDB IDNA
Domain hit(s) vs Pfam Fic [PF02661], Evalue: 3.3e-15, Aligned region: 50..162
Protein Sequence: 533 a.a.     [Download]
>gi|49474589|ref|YP_032631.1| cell filamentation protein [Bartonella quintana str. Toulouse]
MLEHNYFYKNSATLKNKHGIKNPRKLYERCAHETAREAVNFRLEPPPGKFDAAYLRTIHWCLFHNTFEWA
GVTRDQPFTFEDGSTACMPAMRPKGYKVPFAVGSQIQRELKKLEQRLTAKNNLQGLSRQEFAANAAEVFT
ALDHAHPFRKGNGRTQRMFMEKLGQAAGYKIDFSLITKERMTYASIEAMQHNNPEPMKDLFEDITHPQKS
LLLKEFISQMRSARLDEINNHIVLAAKEGVTYDGIYKGSSAEGFVIEVEGGTFIVGHKDDLKPEQVKILQ
NGDFISFQKNNVQNMRETLIPSEILAPLTNEILAERLVNHCGVESYRHEVECLSKIVYGNTQALSQMIET
INIDPSLGEQFVDHIIQNPKSVGKLAGKKILGLRSPARKRAEETVSQLSDTLKSYADIAHQTMADIIEQH
SKEQRRTARSVENPGKDLQNLFALFPEQQREALSHSPTLQQQLHRFSRQLQNRLSSEERRAIQENDCTRL
SCLLGVSASKAKDIAQIVKHTKEAQCQMRTLKVCRSASMALTS
-
Nucleotide Sequence: 1602 bp     [Download]
>gi|49473688|ref|NC_005955.1|:1263630-1265231 Bartonella quintana str. Toulouse, complete genome
ATGTTAGAGCATAATTATTTTTATAAAAACAGCGCAACACTGAAGAATAAACATGGCATAAAAAACCCGC
GAAAACTGTATGAACGCTGTGCTCATGAGACAGCCAGAGAGGCTGTAAATTTTCGCCTTGAACCGCCACC
AGGGAAATTTGATGCCGCTTATCTAAGGACAATTCACTGGTGCCTTTTCCATAACACTTTTGAATGGGCC
GGTGTTACCCGAGATCAGCCCTTTACATTTGAAGATGGCAGCACTGCATGTATGCCAGCTATGCGACCAA
AAGGTTATAAGGTTCCTTTTGCTGTCGGTTCACAAATTCAAAGAGAGCTTAAAAAATTAGAACAAAGACT
AACCGCGAAGAATAATTTACAAGGCTTATCGCGCCAAGAATTTGCTGCAAATGCTGCTGAAGTTTTTACA
GCTCTCGACCACGCGCATCCTTTCAGAAAAGGCAATGGGCGCACACAACGAATGTTTATGGAAAAACTCG
GACAAGCGGCAGGCTATAAGATTGATTTTTCTTTGATCACAAAAGAACGCATGACATATGCCAGCATTGA
AGCAATGCAACATAACAATCCAGAACCCATGAAAGATCTTTTTGAGGATATCACTCACCCTCAAAAATCC
CTTCTTTTAAAGGAATTTATCTCTCAGATGAGAAGCGCTAGACTTGATGAAATTAACAATCATATTGTTT
TGGCAGCAAAAGAAGGTGTGACCTATGATGGCATTTATAAAGGTTCTTCAGCTGAAGGTTTTGTTATAGA
AGTAGAAGGTGGCACTTTCATCGTCGGGCACAAAGATGATCTTAAGCCAGAGCAAGTGAAAATATTACAG
AATGGTGATTTCATCTCCTTTCAGAAAAACAATGTTCAAAACATGAGAGAAACACTTATCCCAAGCGAGA
TATTAGCGCCTCTCACCAATGAGATCCTTGCCGAAAGGCTCGTAAACCATTGTGGGGTTGAATCATACCG
CCATGAAGTCGAGTGTTTATCAAAAATTGTTTATGGCAACACACAAGCATTAAGCCAAATGATTGAGACA
ATCAACATAGATCCAAGTTTAGGCGAACAGTTTGTCGATCACATTATCCAAAATCCTAAATCAGTTGGTA
AGCTTGCCGGGAAAAAAATCCTGGGTCTAAGAAGCCCAGCGCGCAAACGTGCGGAAGAAACTGTTTCACA
GCTGAGTGACACACTTAAAAGTTATGCCGATATAGCACATCAGACCATGGCTGACATCATAGAGCAACAC
TCAAAAGAACAAAGACGCACAGCGCGCTCTGTCGAAAATCCTGGGAAAGACTTGCAAAACCTTTTTGCCT
TGTTCCCAGAACAACAAAGAGAAGCCTTGTCTCATTCCCCTACGCTGCAACAACAACTCCATCGTTTTTC
GCGTCAATTGCAAAATCGTTTATCATCAGAGGAGCGTCGAGCCATACAAGAAAACGATTGCACAAGACTT
TCTTGTCTGCTTGGTGTATCGGCAAGCAAAGCAAAAGACATTGCTCAAATTGTGAAGCATACCAAAGAGG
CACAATGTCAGATGCGTACCCTTAAAGTCTGCCGCTCCGCATCGATGGCTCTGACCAGCTAA

Reference
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] experimental
 
experimental experimental literature