| Effector Protein ID: 49474590 |
 T4SS name [ID] | VirB [31] |
| Gene symbol | - |
| Locus tag | BQ10660 |
| Strain | Bartonella quintana str. Toulouse |
| Replicon | chromosome [GenBank: NC_005955] [Browse all T4SS(s) in this replicon] |
| Location [Strand] | 1265556..1267058 [+] |
| Product | hypothetical protein |
| Effector type | Protein |
| Descripton | BepE |
| T4CP requirement | T4CP Depedent |
| Target/Effection | Homologous to BepE protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. |
| UniProt ID | Q6FYV7 |
| KEGG ID | bqu:BQ10660 |
| PDB ID | NA |
| Domain hit(s) vs Pfam | NA |
| Protein Sequence: 500 a.a. [Download] |
| >gi|49474590|ref|YP_032632.1| hypothetical protein BQ10660 [Bartonella quintana str. Toulouse] MKKNQPSSPSIPRSVEEARRRYEQAPPGSASPPEPLYATVNKKTSHTAKKPEQGAPQAPLFAASSPQRPP RLRDRELHKTTIKEEEIVYASLVHPPHRDHKHPRKNPDNETLYATVAPQSQAMSPTREKEEGIVYASLVH PPHTDHRHPRKNPDNETLYATVASQNLARQSQAMSLTREEMATRIQQSPSVQAYQQEVSHWCQIVFGNSR VLQERVQEILQKPNLAEEVSWQVAENPQAIHKLAGISLCGITNSARRHAEAGLSHLCNAIENYGDAVKQA HENIMHVPHAEARRHGEDRTRSAQSLQQPHHPERGSASLSNEEMLGMVQSHTSIQRYHAQIDYWCKIVFG NSRVLQERVQEILQKPNLAEEVSWQVAENPQAIHKLAGISLCGITNSARRHAEAGLSHLCNAIENYGDAV KQVKESIVQTHQTRQNRQEQASGLSQSVQKQQTLSKPPKLPERPAVTARNEETSRQQAHQKAPDVRPRRI RETKAIAFAS |
| - |
| Nucleotide Sequence: 1503 bp [Download] |
| >gi|49473688|ref|NC_005955.1|:1265556-1267058 Bartonella quintana str. Toulouse, complete genome ATGAAAAAAAACCAACCATCCTCTCCTTCTATCCCCCGTTCTGTGGAAGAAGCAAGAAGACGTTATGAAC AAGCTCCTCCCGGAAGCGCATCTCCACCAGAACCCCTGTACGCAACAGTGAACAAAAAAACATCTCATAC AGCGAAAAAGCCAGAACAAGGAGCGCCACAAGCGCCTCTCTTCGCAGCGAGTTCTCCACAAAGGCCGCCT CGCCTGAGAGACAGGGAGCTCCATAAAACAACAATCAAAGAGGAGGAAATCGTATATGCATCGCTTGTTC ATCCGCCTCACAGGGACCACAAACACCCGAGAAAGAATCCAGACAACGAAACCCTCTACGCAACGGTTGC TCCCCAAAGTCAAGCAATGTCTCCCACGAGAGAGAAAGAGGAGGGGATAGTATATGCATCGCTTGTTCAT CCACCTCACACGGACCACAGACACCCGAGAAAGAATCCAGACAATGAAACCCTTTACGCAACGGTTGCTT CTCAAAATCTAGCTCGCCAAAGTCAAGCAATGTCTCTCACGAGAGAGGAAATGGCGACCAGGATTCAACA GAGCCCATCGGTCCAAGCATATCAACAAGAAGTCTCACATTGGTGCCAAATTGTTTTTGGCAATTCGCGT GTTTTGCAAGAAAGAGTGCAGGAGATTCTCCAAAAACCCAATTTGGCAGAAGAGGTCTCATGGCAAGTTG CAGAAAATCCCCAGGCTATTCATAAGCTTGCAGGGATTAGTCTGTGTGGCATAACAAATAGTGCCCGCAG ACATGCTGAAGCAGGCCTTTCACATCTTTGTAATGCCATTGAAAACTATGGAGATGCTGTAAAACAAGCA CACGAAAACATTATGCACGTTCCTCACGCGGAAGCAAGACGTCATGGAGAGGACAGGACACGCAGTGCCC AAAGTCTGCAACAGCCGCATCATCCTGAAAGGGGAAGTGCATCTCTCTCAAATGAGGAAATGCTGGGGAT GGTTCAAAGCCATACATCCATCCAAAGATATCATGCACAAATTGACTATTGGTGCAAAATTGTTTTTGGC AATTCGCGTGTTTTGCAAGAAAGAGTACAGGAGATTCTCCAAAAACCCAATTTGGCAGAAGAGGTCTCAT GGCAAGTTGCAGAAAATCCCCAGGCTATTCATAAGCTTGCAGGGATTAGTCTGTGTGGCATAACAAATAG TGCCCGCAGACATGCTGAAGCAGGCCTTTCACATCTTTGTAATGCCATTGAAAACTATGGAGATGCTGTA AAACAAGTAAAGGAAAGTATTGTGCAGACGCACCAGACGAGGCAAAATCGCCAAGAACAGGCTTCTGGAT TGTCTCAGAGCGTGCAAAAACAACAAACCTTGTCTAAGCCTCCTAAACTGCCTGAACGTCCAGCTGTAAC CGCACGTAATGAGGAAACTTCCAGACAGCAAGCACACCAGAAAGCACCAGATGTTCGACCTCGCAGAATT CGGGAAACGAAAGCAATAGCTTTCGCCAGCTAA |
| Reference |
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] 
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| experimental literature |