SecReT4
Effector Protein ID: 49474590
T4SS name [ID]VirB [31]
Gene symbol-
Locus tagBQ10660
StrainBartonella quintana str. Toulouse
Repliconchromosome [GenBank: NC_005955] [Browse all T4SS(s) in this replicon]
Location [Strand]1265556..1267058 [+]
Producthypothetical protein
Effector typeProtein
DescriptonBepE
T4CP requirementT4CP Depedent
Target/EffectionHomologous to BepE protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells.
UniProt IDQ6FYV7
KEGG IDbqu:BQ10660
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 500 a.a.     [Download]
>gi|49474590|ref|YP_032632.1| hypothetical protein BQ10660 [Bartonella quintana str. Toulouse]
MKKNQPSSPSIPRSVEEARRRYEQAPPGSASPPEPLYATVNKKTSHTAKKPEQGAPQAPLFAASSPQRPP
RLRDRELHKTTIKEEEIVYASLVHPPHRDHKHPRKNPDNETLYATVAPQSQAMSPTREKEEGIVYASLVH
PPHTDHRHPRKNPDNETLYATVASQNLARQSQAMSLTREEMATRIQQSPSVQAYQQEVSHWCQIVFGNSR
VLQERVQEILQKPNLAEEVSWQVAENPQAIHKLAGISLCGITNSARRHAEAGLSHLCNAIENYGDAVKQA
HENIMHVPHAEARRHGEDRTRSAQSLQQPHHPERGSASLSNEEMLGMVQSHTSIQRYHAQIDYWCKIVFG
NSRVLQERVQEILQKPNLAEEVSWQVAENPQAIHKLAGISLCGITNSARRHAEAGLSHLCNAIENYGDAV
KQVKESIVQTHQTRQNRQEQASGLSQSVQKQQTLSKPPKLPERPAVTARNEETSRQQAHQKAPDVRPRRI
RETKAIAFAS
-
Nucleotide Sequence: 1503 bp     [Download]
>gi|49473688|ref|NC_005955.1|:1265556-1267058 Bartonella quintana str. Toulouse, complete genome
ATGAAAAAAAACCAACCATCCTCTCCTTCTATCCCCCGTTCTGTGGAAGAAGCAAGAAGACGTTATGAAC
AAGCTCCTCCCGGAAGCGCATCTCCACCAGAACCCCTGTACGCAACAGTGAACAAAAAAACATCTCATAC
AGCGAAAAAGCCAGAACAAGGAGCGCCACAAGCGCCTCTCTTCGCAGCGAGTTCTCCACAAAGGCCGCCT
CGCCTGAGAGACAGGGAGCTCCATAAAACAACAATCAAAGAGGAGGAAATCGTATATGCATCGCTTGTTC
ATCCGCCTCACAGGGACCACAAACACCCGAGAAAGAATCCAGACAACGAAACCCTCTACGCAACGGTTGC
TCCCCAAAGTCAAGCAATGTCTCCCACGAGAGAGAAAGAGGAGGGGATAGTATATGCATCGCTTGTTCAT
CCACCTCACACGGACCACAGACACCCGAGAAAGAATCCAGACAATGAAACCCTTTACGCAACGGTTGCTT
CTCAAAATCTAGCTCGCCAAAGTCAAGCAATGTCTCTCACGAGAGAGGAAATGGCGACCAGGATTCAACA
GAGCCCATCGGTCCAAGCATATCAACAAGAAGTCTCACATTGGTGCCAAATTGTTTTTGGCAATTCGCGT
GTTTTGCAAGAAAGAGTGCAGGAGATTCTCCAAAAACCCAATTTGGCAGAAGAGGTCTCATGGCAAGTTG
CAGAAAATCCCCAGGCTATTCATAAGCTTGCAGGGATTAGTCTGTGTGGCATAACAAATAGTGCCCGCAG
ACATGCTGAAGCAGGCCTTTCACATCTTTGTAATGCCATTGAAAACTATGGAGATGCTGTAAAACAAGCA
CACGAAAACATTATGCACGTTCCTCACGCGGAAGCAAGACGTCATGGAGAGGACAGGACACGCAGTGCCC
AAAGTCTGCAACAGCCGCATCATCCTGAAAGGGGAAGTGCATCTCTCTCAAATGAGGAAATGCTGGGGAT
GGTTCAAAGCCATACATCCATCCAAAGATATCATGCACAAATTGACTATTGGTGCAAAATTGTTTTTGGC
AATTCGCGTGTTTTGCAAGAAAGAGTACAGGAGATTCTCCAAAAACCCAATTTGGCAGAAGAGGTCTCAT
GGCAAGTTGCAGAAAATCCCCAGGCTATTCATAAGCTTGCAGGGATTAGTCTGTGTGGCATAACAAATAG
TGCCCGCAGACATGCTGAAGCAGGCCTTTCACATCTTTGTAATGCCATTGAAAACTATGGAGATGCTGTA
AAACAAGTAAAGGAAAGTATTGTGCAGACGCACCAGACGAGGCAAAATCGCCAAGAACAGGCTTCTGGAT
TGTCTCAGAGCGTGCAAAAACAACAAACCTTGTCTAAGCCTCCTAAACTGCCTGAACGTCCAGCTGTAAC
CGCACGTAATGAGGAAACTTCCAGACAGCAAGCACACCAGAAAGCACCAGATGTTCGACCTCGCAGAATT
CGGGAAACGAAAGCAATAGCTTTCGCCAGCTAA

Reference
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] experimental
 
experimental experimental literature