SecReT4
Effector Protein ID: 49474592
T4SS name [ID]VirB [31]
Gene symbol-
Locus tagBQ10680
StrainBartonella quintana str. Toulouse
Repliconchromosome [GenBank: NC_005955] [Browse all T4SS(s) in this replicon]
Location [Strand]1269465..1271246 [+]
Producthypothetical protein
Effector typeProtein
DescriptonBepF
T4CP requirementT4CP Depedent
Target/EffectionHomologous to BepF protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells.
UniProt IDQ6FYV5
KEGG IDbqu:BQ10680
PDB IDNA
Domain hit(s) vs Pfam NA
Protein Sequence: 593 a.a.     [Download]
>gi|49474592|ref|YP_032634.1| hypothetical protein BQ10680 [Bartonella quintana str. Toulouse]
MKKNQPAPSAPLSVKELKKRYEQPATRTPFPETLSARISPKDKRQPSPKLEELKKRYEHPPTETSSSESL
SATVAPQRPLRMKEKLAKMEQTRETADAKIVPPQRPPRMKDKLAQMEQARKTADAKIVPPQRPPRMKDKL
AQMEQAREIGDATAAPPKPPRMKDKLAKIEQAREIGDATAAPPKPPRMKDKLAKIEQARETADAMAAPPK
PPRMKDKLAQMEQARKTADAIAAPPKPPRMKARGQSNIAAESETLYATAAPQKPLHMRKTLVNTMEQKLL
IDAYQEEIRYWCGMVYGDRLILDERMEEVQKNPALGEQLSREVAENPQSIAQFAGKKMLGLKTKARREAE
ENFSSLCATLEGYVYTVKYSQETTMHVPHAEQSHHEEPTQRGQRAENLRKPLHPEKEMAPLSNKEIAHKI
QKDPSVQYAQAEVCYWCKIAYGDPSILQERIEEIQKIPGMGEELSWQVANHPTFFHKLAGRQMLGIKNQT
RKKAEEGLSTLCSAIENYADIVKQVRDNIVQTHQAQQNCQEQSVELAQDLQKQQALSKQPKLPEHSAVTA
RHEGVEASRQAQQQSPDVRPRKVGAAKAMAFAS
-
Nucleotide Sequence: 1782 bp     [Download]
>gi|49473688|ref|NC_005955.1|:1269465-1271246 Bartonella quintana str. Toulouse, complete genome
ATGAAAAAAAACCAACCAGCCCCTTCTGCACCTCTTTCGGTGAAAGAATTAAAAAAACGCTACGAACAGC
CTGCCACAAGAACACCCTTTCCAGAAACCCTATCTGCAAGGATTTCTCCAAAAGACAAAAGACAGCCTTC
CCCGAAACTGGAAGAATTAAAAAAACGCTATGAACACCCTCCCACAGAAACATCTTCTTCAGAATCTCTA
TCTGCAACGGTTGCCCCACAAAGACCACTTCGCATGAAAGAGAAATTGGCTAAAATGGAACAAACCAGAG
AAACTGCAGATGCAAAGATTGTCCCACCACAAAGACCACCTCGCATGAAAGACAAATTGGCTCAGATGGA
GCAAGCCAGAAAAACTGCAGATGCAAAGATTGTCCCACCACAAAGACCACCTCGCATGAAAGACAAATTG
GCTCAGATGGAGCAAGCCAGAGAAATTGGAGACGCAACTGCTGCTCCACCAAAGCCACCTCGCATGAAAG
ACAAATTGGCTAAAATAGAACAAGCCAGAGAAATTGGAGACGCAACCGCTGCTCCACCAAAGCCACCTCG
CATGAAAGACAAATTGGCTAAAATAGAACAAGCCAGAGAAACTGCAGATGCAATGGCTGCTCCACCAAAG
CCACCTCGCATGAAAGACAAATTGGCTCAGATGGAGCAAGCCAGAAAAACTGCAGATGCAATAGCTGCTC
CACCAAAGCCACCTCGCATGAAAGCCAGAGGGCAAAGCAATATCGCCGCAGAAAGTGAAACCCTTTACGC
TACAGCTGCTCCGCAAAAACCACTTCACATGAGAAAGACACTTGTTAACACAATGGAACAAAAGCTCTTG
ATCGACGCATATCAGGAAGAAATTCGATATTGGTGCGGAATGGTTTATGGCGATCGGCTTATTTTAGACG
AAAGAATGGAAGAGGTTCAAAAAAACCCTGCTCTGGGAGAACAGCTCTCACGAGAAGTTGCAGAAAATCC
CCAGTCTATTGCTCAATTCGCTGGTAAAAAAATGCTTGGCTTGAAAACGAAGGCACGCAGAGAAGCTGAA
GAAAATTTTTCATCTCTTTGTGCTACTCTTGAGGGTTATGTATATACTGTAAAATACTCACAAGAAACCA
CTATGCATGTTCCTCATGCAGAACAAAGCCACCATGAAGAACCAACACAGAGAGGACAAAGAGCTGAAAA
TCTACGAAAGCCGCTTCATCCTGAAAAGGAGATGGCACCTCTTTCGAATAAGGAAATTGCCCACAAGATT
CAAAAAGATCCATCGGTTCAATATGCTCAAGCAGAAGTCTGCTATTGGTGCAAAATCGCTTATGGCGACC
CGAGTATTTTGCAGGAAAGAATTGAAGAGATTCAAAAAATTCCCGGCATGGGAGAAGAGCTTTCATGGCA
AGTTGCAAACCATCCTACGTTTTTTCATAAGCTTGCGGGTAGGCAAATGCTTGGCATAAAAAATCAAACA
CGCAAAAAAGCCGAAGAAGGTCTTTCTACCTTATGTAGTGCCATTGAAAATTATGCGGACATTGTAAAAC
AAGTAAGAGACAATATTGTGCAAACCCATCAAGCACAACAAAACTGCCAAGAACAGTCTGTGGAATTGGC
TCAAGACTTGCAAAAACAGCAAGCTTTATCAAAGCAGCCTAAGCTGCCTGAGCATTCAGCAGTTACTGCG
CGTCATGAGGGTGTAGAAGCCTCCAGGCAAGCACAGCAGCAATCGCCAGACGTTCGACCACGCAAAGTTG
GGGCAGCAAAAGCAATGGCTTTTGCCAGCTAA

Reference
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] experimental
 
experimental experimental literature