Effector Protein ID: 49474591 |
T4SS name [ID] | VirB [31] |
Gene symbol | - |
Locus tag | BQ10670 |
Strain | Bartonella quintana str. Toulouse |
Replicon | chromosome [GenBank: NC_005955] [Browse all T4SS(s) in this replicon] |
Location [Strand] | 1267412..1269157 [+] |
Product | hypothetical protein |
Effector type | Protein |
Descripton | BepF |
T4CP requirement | T4CP Depedent |
Target/Effection | Homologous to BepF protein of Bartonella henselae. The Bartonella-translocated effector protein (BepA-BepG) are required for invasion, proinflammatory activation and antiapoptotic protection of endothelial cells. |
UniProt ID | Q6FYV6 |
KEGG ID | bqu:BQ10670 |
PDB ID | NA |
Domain hit(s) vs Pfam | NA |
Protein Sequence: 581 a.a. [Download] |
>gi|49474591|ref|YP_032633.1| hypothetical protein BQ10670 [Bartonella quintana str. Toulouse] MKKKPLPSAFPAVKELRKRYEQSVAETSTPESLSPRISPKDKRQPVSKLEELRKRHEQSAVTPEQSLLQA LLYPTPPPQQPMRTKDREKSTAAVQEGEALYARAAPQKPPRAKDKEKNTAPIQGGEALYARAAPQRPPRA KDKEKNTAPIQGGEALYARAAPQRPPRAKDKEKNTAPIQGGEALYARAAPQRPPRAKDKEKNTAPIQGGE ALYAMAAPQRPPRAKDKEKNTAPIQGGEALYAMAAPQKKKTILSKDEISKRLQGSVSIQYCEAEIQHWCR VVYGNPHALKEEIATIKENPMFGEQLSWEVANHPTSFSKLAGNKMLGIKNSARKEAEAGLPSLCNAIGDY AKTVKREKESILQNYHAEQKRHEQPMERVQMVKKPRKPLHLEKEMAPLSNKEIAYKIQRDISVQYGQAEI QYWCHIVYDNPCLLRERTEEIQKNPAMGEELSWQVANHPTFFAKFAGHQTLGIKNEARKKAEAGLSSLCN ALDSYTNAVKQAKESIIKEHQEKQNRQGQSAGLAQELQKKQHALSKWPKLPEHSTVTARHESGETSRQVD SKPPDVRPRKVGTTKAMAFTH |
- |
Nucleotide Sequence: 1746 bp [Download] |
>gi|49473688|ref|NC_005955.1|:1267412-1269157 Bartonella quintana str. Toulouse, complete genome ATGAAAAAAAAACCACTCCCTTCAGCATTTCCTGCAGTGAAAGAATTAAGAAAACGCTATGAACAATCTG TGGCAGAAACATCTACTCCAGAAAGCTTATCGCCAAGGATTTCTCCAAAAGACAAAAGACAGCCTGTCTC GAAACTGGAAGAATTAAGAAAACGCCATGAACAATCTGCCGTTACACCAGAACAAAGCTTGCTACAAGCA CTTCTCTACCCAACACCTCCTCCACAGCAACCAATGCGCACCAAAGATAGAGAGAAGAGCACCGCAGCTG TTCAAGAGGGTGAAGCTCTCTACGCAAGGGCTGCTCCACAAAAGCCACCTCGTGCAAAAGATAAAGAGAA AAATACCGCACCCATCCAAGGGGGTGAAGCTCTCTACGCAAGGGCTGCTCCACAAAGGCCACCTCGTGCA AAAGATAAAGAGAAAAACACCGCACCCATCCAAGGGGGTGAAGCTCTCTACGCAAGGGCTGCTCCACAAA GGCCACCTCGTGCAAAAGATAAAGAGAAAAATACCGCACCCATCCAAGGGGGTGAAGCTCTCTACGCAAG GGCTGCTCCACAAAGGCCACCTCGTGCAAAAGATAAAGAGAAAAACACCGCACCCATCCAAGGGGGTGAA GCCCTCTACGCCATGGCTGCTCCACAAAGGCCACCTCGTGCAAAAGATAAAGAGAAAAACACCGCACCCA TCCAAGGGGGTGAAGCCCTCTACGCCATGGCTGCTCCACAAAAGAAAAAAACGATTCTCTCGAAAGACGA GATTTCGAAAAGGCTTCAGGGAAGCGTATCGATCCAATATTGTGAAGCAGAAATTCAACATTGGTGTAGA GTTGTTTATGGTAACCCACACGCTCTAAAGGAAGAAATTGCAACGATTAAAGAAAACCCCATGTTTGGAG AACAGCTCTCATGGGAAGTTGCAAATCATCCTACATCTTTCTCTAAGCTTGCGGGTAACAAAATGCTTGG CATAAAAAACAGCGCACGCAAAGAAGCTGAAGCAGGTCTTCCTTCCCTCTGTAACGCCATTGGCGATTAT GCAAAGACTGTAAAAAGGGAAAAAGAGAGCATCTTGCAAAATTATCATGCCGAGCAAAAACGCCATGAAC AACCGATGGAGAGGGTGCAAATGGTCAAAAAGCCGCGAAAGCCACTTCATCTTGAAAAGGAAATGGCTCC TCTTTCGAACAAAGAAATTGCTTACAAGATTCAAAGAGATATATCGGTTCAATATGGTCAAGCAGAAATA CAATATTGGTGCCACATTGTTTATGACAATCCGTGTCTCTTGCGGGAAAGGACAGAGGAGATCCAAAAAA ATCCTGCTATGGGAGAAGAGCTTTCATGGCAAGTTGCAAATCATCCTACGTTTTTTGCTAAGTTCGCGGG TCACCAAACGCTTGGCATAAAAAACGAGGCGCGCAAAAAAGCTGAAGCAGGTCTTTCTTCCCTTTGTAAC GCTCTTGACAGTTATACAAATGCTGTAAAACAAGCAAAAGAGAGCATTATCAAGGAACATCAAGAAAAAC AAAATCGCCAAGGACAGTCTGCTGGGTTAGCGCAAGAATTGCAAAAAAAGCAGCACGCTTTATCAAAGTG GCCTAAACTGCCTGAGCATTCAACAGTCACCGCGCGTCATGAGAGTGGAGAAACCTCCAGACAAGTAGAC AGCAAACCGCCTGACGTTCGACCACGCAAAGTTGGGACAACAAAAGCAATGGCTTTCACTCACTAA |
Reference |
(1) Saenz HL; Engel P; Stoeckli MC; Lanz C; Raddatz G; Vayssier-Taussat M; Birtles R; Schuster SC; Dehio C (2007). Genomic analysis of Bartonella identifies type IV secretion systems as host adaptability factors. Nat Genet. 39(12):1469-76. [PudMed:18037886] |
experimental literature |