CagM |
CagM is a component of Cag T4SS. CagM is a outer membrane complex preotein characterized by a putative N-terminal signal sequence, and at least three transmembrane helices can be predicted from the sequence pattern. Systematic mutagenesis analysis clearly showed that cagM-knock out mutants are neither able to produce an efficient CagA translocation, nor to release peptidoglycan degradation fragments |