Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGD   Type   Machinery gene
Locus tag   EL070_RS00695 Genome accession   NZ_LR134284
Coordinates   106597..107025 (+) Length   142 a.a.
NCBI ID   WP_002986548.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8232     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 101597..112025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL070_RS00675 (NCTC8232_00134) - 103928..104293 (+) 366 WP_111705425.1 DUF1033 family protein -
  EL070_RS00680 (NCTC8232_00135) comGA 104386..105324 (+) 939 WP_002987773.1 competence type IV pilus ATPase ComGA Machinery gene
  EL070_RS00685 (NCTC8232_00136) comGB 105260..106294 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  EL070_RS00690 (NCTC8232_00137) comGC 106296..106622 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  EL070_RS00695 (NCTC8232_00138) comGD 106597..107025 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD Machinery gene
  EL070_RS00700 (NCTC8232_00139) comGE 106982..107266 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE Machinery gene
  EL070_RS00705 (NCTC8232_00140) comGF 107259..107693 (+) 435 WP_002986542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EL070_RS00710 (NCTC8232_00141) comGG 107677..108003 (+) 327 WP_002986539.1 competence type IV pilus minor pilin ComGG -
  EL070_RS00715 (NCTC8232_00142) comGH 108101..109054 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  EL070_RS00720 (NCTC8232_00143) - 109113..110309 (+) 1197 WP_002986533.1 acetate kinase -
  EL070_RS00725 - 110496..110804 (+) 309 Protein_92 hypothetical protein -
  EL070_RS00730 (NCTC8232_00144) proC 110887..111657 (-) 771 WP_111705426.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 142 a.a.        Molecular weight: 16310.04 Da        Isoelectric Point: 10.3481

>NTDB_id=999989 EL070_RS00695 WP_002986548.1 106597..107025(+) (comGD) [Streptococcus pyogenes strain NCTC8232]
MKKPVLAIKAFTLLETLLSLSVMSFIILGLSVPVTKSYQKVEEHLFFSHFEHLYRHQQKLAILQQKQRVLDISSTKIVTE
GNSLTVPKSITVNHPYRLVIDQMGGNHSLAKIIFDMTDRRFKYQFYLGSGNYQKTSQSLHSP

Nucleotide


Download         Length: 429 bp        

>NTDB_id=999989 EL070_RS00695 WP_002986548.1 106597..107025(+) (comGD) [Streptococcus pyogenes strain NCTC8232]
ATGAAAAAGCCCGTCTTAGCAATTAAAGCTTTTACTTTGCTTGAAACTTTACTAAGTTTGTCAGTGATGAGTTTCATTAT
ATTGGGATTGTCTGTACCAGTGACAAAAAGCTATCAAAAAGTAGAAGAGCATCTGTTTTTTAGCCATTTTGAACATTTGT
ATCGACATCAGCAAAAGTTAGCCATATTACAGCAAAAACAGCGCGTCTTGGATATTTCTTCAACAAAAATTGTTACAGAA
GGTAATAGCCTAACAGTTCCTAAATCAATAACAGTGAATCATCCTTATCGGTTAGTTATTGATCAGATGGGAGGCAACCA
TTCCTTAGCTAAAATTATTTTTGACATGACTGATCGACGCTTTAAATACCAATTTTATCTAGGGAGTGGGAATTATCAAA
AAACAAGTCAAAGCTTACATAGCCCTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGD Streptococcus mutans UA159

45.736

90.845

0.415
  comGD Streptococcus mutans UA140

45.736

90.845

0.415
  comGD/cglD Streptococcus mitis NCTC 12261

40.441

95.775

0.387
  comGD Streptococcus gordonii str. Challis substr. CH1

40.458

92.254

0.373
  comGD/cglD Streptococcus mitis SK321

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae Rx1

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae D39

39.695

92.254

0.366
  comGD/cglD Streptococcus pneumoniae R6

39.695

92.254

0.366

Multiple sequence alignment