Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvB   Type   Machinery gene
Locus tag   ELZ63_RS01955 Genome accession   NZ_LR134171
Coordinates   383526..384533 (+) Length   335 a.a.
NCBI ID   WP_005649027.1    Uniprot ID   Q4QNM6
Organism   Haemophilus influenzae strain NCTC12699     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 378526..389533
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ63_RS01930 (NCTC12699_00386) aspS 379209..380975 (+) 1767 WP_061724194.1 aspartate--tRNA ligase -
  ELZ63_RS01935 (NCTC12699_00387) nudB 380997..381470 (+) 474 WP_061724192.1 dihydroneopterin triphosphate diphosphatase -
  ELZ63_RS01940 (NCTC12699_00388) - 381482..382222 (+) 741 WP_005662961.1 YebC/PmpR family DNA-binding transcriptional regulator -
  ELZ63_RS01945 (NCTC12699_00389) ruvC 382269..382841 (+) 573 WP_065245003.1 crossover junction endodeoxyribonuclease RuvC -
  ELZ63_RS01950 (NCTC12699_00390) ruvA 382904..383518 (+) 615 WP_005659994.1 Holliday junction branch migration protein RuvA Machinery gene
  ELZ63_RS01955 (NCTC12699_00391) ruvB 383526..384533 (+) 1008 WP_005649027.1 Holliday junction branch migration DNA helicase RuvB Machinery gene
  ELZ63_RS01960 (NCTC12699_00392) - 384588..384872 (-) 285 WP_061724188.1 DUF5339 domain-containing protein -
  ELZ63_RS01965 (NCTC12699_00393) xerD 385045..385938 (-) 894 WP_005668988.1 site-specific tyrosine recombinase XerD -
  ELZ63_RS01970 (NCTC12699_00394) - 385969..387135 (-) 1167 WP_061724186.1 3-phenylpropionate MFS transporter -
  ELZ63_RS01975 (NCTC12699_00395) proC 387135..387950 (-) 816 WP_005662973.1 pyrroline-5-carboxylate reductase -
  ELZ63_RS01980 (NCTC12699_00396) rdgC 388016..388924 (+) 909 WP_005662977.1 recombination-associated protein RdgC -
  ELZ63_RS01985 (NCTC12699_00397) ruvX 388974..389393 (-) 420 WP_005648994.1 Holliday junction resolvase RuvX -

Sequence

Protein


Download         Length: 335 a.a.        Molecular weight: 37076.41 Da        Isoelectric Point: 4.7793

>NTDB_id=998049 ELZ63_RS01955 WP_005649027.1 383526..384533(+) (ruvB) [Haemophilus influenzae strain NCTC12699]
MIEADRIISGQAKVDEDVIDRAIRPKLLADYVGQPQVREQMDIFIKAAKLRQDALDHLLIFGPPGLGKTTLANIVANEMG
VNIRTTSGPVLEKAGDLAAMLTNLEPHDVLFIDEIHRLSPAIEEVLYPAMEDYQLDIMIGEGPAARSIKLDLPPFTLVGA
TTRAGSLTSPLRDRFGIVQRLEFYSVEDLTSIVARSADCLNLELEQQAAFEVARRSRGTPRIANRLLRRVRDYADVRNGG
IISINVAKQALSMLDVDDAGFDYLDRKLLSAVIERFDGGPVGLDNLAAAIGEERDTIEDVLEPYLIQQGFLQRTPRGRIA
TSQTYRHFGLQKLSD

Nucleotide


Download         Length: 1008 bp        

>NTDB_id=998049 ELZ63_RS01955 WP_005649027.1 383526..384533(+) (ruvB) [Haemophilus influenzae strain NCTC12699]
ATGATTGAAGCAGATAGAATTATTAGTGGGCAAGCTAAGGTTGATGAAGATGTTATCGACCGTGCTATTCGTCCTAAACT
ATTAGCAGATTATGTTGGGCAGCCGCAAGTACGCGAGCAGATGGATATTTTCATCAAGGCAGCCAAACTACGTCAAGATG
CCTTAGATCATTTATTGATTTTTGGCCCTCCAGGTTTGGGAAAAACAACGCTTGCTAATATTGTGGCAAATGAAATGGGC
GTGAATATTCGTACGACGTCAGGGCCTGTATTAGAAAAAGCGGGAGATTTAGCCGCAATGCTAACCAATCTTGAACCGCA
TGATGTGTTATTTATTGATGAAATCCATCGACTTTCCCCTGCTATTGAAGAAGTCCTTTATCCAGCAATGGAAGACTATC
AGTTGGATATTATGATTGGTGAAGGGCCTGCCGCTCGTTCCATTAAATTAGATTTGCCCCCTTTTACTTTGGTTGGTGCG
ACCACTAGAGCGGGTTCTTTGACTTCACCATTGCGTGATCGTTTTGGTATTGTGCAACGTTTGGAATTCTATTCTGTAGA
AGATTTAACATCTATCGTTGCAAGAAGTGCGGACTGTTTAAATCTTGAATTAGAACAACAAGCCGCTTTCGAGGTGGCTC
GTCGTTCACGAGGCACGCCTCGAATTGCAAACCGTTTATTACGACGTGTGCGTGATTATGCGGATGTACGTAATGGCGGT
ATTATTTCTATAAATGTGGCAAAACAAGCACTTTCAATGCTAGATGTAGACGATGCTGGATTTGATTATTTAGATAGAAA
GTTGTTGTCTGCAGTTATTGAGCGTTTTGATGGTGGCCCTGTGGGACTAGATAATCTTGCTGCTGCAATTGGTGAAGAAC
GTGATACCATTGAAGATGTGTTAGAGCCTTATTTGATTCAACAGGGGTTTCTACAAAGAACGCCGCGAGGTCGTATTGCA
ACATCGCAAACTTATCGTCATTTTGGTTTGCAGAAATTATCAGACTAG

Domains

Predicted by InterProScan.

Holliday junction DNA helicase RuvB P-loop domain (RuvB_N)

(23-181)

RuvB C-terminal winged helix domain (WHD_RuvB)

(259-328)

RuvB AAA lid domain (AAA_lid_4)

(184-257)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q4QNM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvB Bacillus subtilis subsp. subtilis str. 168

62.385

97.612

0.609
  ruvB Streptococcus pneumoniae TIGR4

57.975

97.313

0.564
  ruvB Streptococcus pneumoniae R6

57.975

97.313

0.564
  ruvB Streptococcus pneumoniae D39

57.975

97.313

0.564
  ruvB Helicobacter pylori 26695

54.633

93.433

0.51
  ruvB Synechocystis sp. PCC 6803

55.016

92.239

0.507