Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ELZ51_RS10075 Genome accession   NZ_LR134094
Coordinates   1989489..1990229 (-) Length   246 a.a.
NCBI ID   WP_126427374.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1984489..1995229
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ELZ51_RS10045 (NCTC4669_02122) - 1985384..1986088 (-) 705 WP_126427371.1 N-acetylmannosamine-6-phosphate 2-epimerase -
  ELZ51_RS10055 (NCTC4669_02123) rpmH 1986419..1986553 (-) 135 WP_002885866.1 50S ribosomal protein L34 -
  ELZ51_RS10060 (NCTC4669_02124) jag 1986867..1987781 (-) 915 WP_003052890.1 RNA-binding cell elongation regulator Jag/EloR -
  ELZ51_RS10065 (NCTC4669_02125) - 1987793..1988620 (-) 828 WP_115253145.1 YidC/Oxa1 family membrane protein insertase -
  ELZ51_RS10070 (NCTC4669_02126) rnpA 1988586..1988945 (-) 360 WP_126427372.1 ribonuclease P protein component -
  ELZ51_RS10075 (NCTC4669_02127) comE/blpR 1989489..1990229 (-) 741 WP_126427374.1 response regulator transcription factor Regulator
  ELZ51_RS10080 (NCTC4669_02128) - 1990233..1991516 (-) 1284 WP_126427376.1 sensor histidine kinase -
  ELZ51_RS10085 (NCTC4669_02129) - 1991517..1992860 (-) 1344 WP_115245614.1 sensor histidine kinase -
  ELZ51_RS10090 (NCTC4669_02130) gltX 1993473..1994921 (-) 1449 WP_126427378.1 glutamate--tRNA ligase -

Sequence

Protein


Download         Length: 246 a.a.        Molecular weight: 28897.25 Da        Isoelectric Point: 4.7814

>NTDB_id=997779 ELZ51_RS10075 WP_126427374.1 1989489..1990229(-) (comE/blpR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MMNIFILEDDFIQQTRIESVVADILEEAKLLCNQLEVFANPHKLFESIQERGDHQLYFLDIEIGDEARRGLELAADIRQK
DPNAVIVFVTTHSEFAPISFKYKVSALDFIDKAVDKEQFRDQIEECIRYTYEMMSSRESEDMFLFETPQTRLKLPYKDIL
YFATATTPHKVCLWTQTERLEFYGNLSEIQAVAPKLFLCHRSYLVNLDKVVRIDKSKQLLYFDNGDSCMVSCLKMKCLFE
KWEALH

Nucleotide


Download         Length: 741 bp        

>NTDB_id=997779 ELZ51_RS10075 WP_126427374.1 1989489..1990229(-) (comE/blpR) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
ATGATGAATATTTTTATTCTTGAAGATGATTTTATTCAACAGACACGTATTGAATCTGTAGTGGCAGACATTTTGGAAGA
GGCTAAATTACTTTGTAATCAGCTAGAAGTGTTTGCCAATCCTCATAAATTATTTGAAAGCATTCAAGAAAGAGGCGACC
ATCAGTTATATTTTTTAGATATTGAGATTGGTGATGAGGCTCGTCGAGGACTTGAATTGGCAGCAGATATTCGACAAAAA
GACCCCAATGCAGTCATTGTGTTTGTTACTACACATTCTGAATTTGCTCCTATTTCTTTTAAATACAAAGTGTCTGCCTT
AGATTTTATTGACAAAGCAGTTGATAAAGAACAATTTAGGGATCAGATTGAAGAATGTATCCGCTATACCTATGAGATGA
TGTCTAGCCGTGAATCAGAAGATATGTTTTTATTTGAGACCCCTCAGACAAGATTGAAATTACCTTACAAAGATATCCTT
TATTTTGCCACTGCTACGACACCTCATAAGGTGTGTTTGTGGACTCAGACGGAGAGACTGGAGTTTTATGGCAATTTATC
TGAGATACAAGCCGTGGCTCCAAAACTTTTCTTATGTCATAGATCTTACTTGGTTAATCTAGATAAGGTTGTGCGTATTG
ATAAATCCAAACAGCTCCTCTATTTTGATAATGGAGATTCCTGCATGGTCTCATGCTTAAAAATGAAATGCCTTTTTGAA
AAATGGGAGGCCTTACATTAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.699

97.154

0.463
  comE/comE1 Streptococcus equinus JB1

42.437

96.748

0.411
  comE/comE2 Streptococcus equinus JB1

40

99.593

0.398
  comE/comE2 Streptococcus gordonii strain NCTC7865

39.113

100

0.394
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

39.113

100

0.394

Multiple sequence alignment