Detailed information NTG0997702

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: ELZ51_RS00875
• Genome accession: NZ_LR134094
• Coordinates: 133117..133557 (+)
• Length: 146 a.a.
• NCBI ID: WP_003049266.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 128117..138557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ELZ51_RS00845 (NCTC4669_00179)	-	129798..130163 (+)	366	WP_126425649.1	DUF1033 family protein	-
ELZ51_RS00850 (NCTC4669_00180)	comGA	130244..131185 (+)	942	WP_126425651.1	competence type IV pilus ATPase ComGA	Machinery gene
ELZ51_RS00855 (NCTC4669_00181)	comGB	131121..132152 (+)	1032	WP_126427580.1	competence type IV pilus assembly protein ComGB	Machinery gene
ELZ51_RS00860 (NCTC4669_00182)	comGC	132154..132480 (+)	327	WP_115246891.1	competence type IV pilus major pilin ComGC	Machinery gene
ELZ51_RS00865 (NCTC4669_00183)	comGD	132455..132883 (+)	429	WP_115252504.1	competence type IV pilus minor pilin ComGD	Machinery gene
ELZ51_RS00870 (NCTC4669_00184)	comGE	132840..133136 (+)	297	WP_003061797.1	competence type IV pilus minor pilin ComGE	Machinery gene
ELZ51_RS00875 (NCTC4669_00185)	comGF	133117..133557 (+)	441	WP_003049266.1	competence type IV pilus minor pilin ComGF	Machinery gene
ELZ51_RS00880 (NCTC4669_00186)	comGG	133580..133909 (+)	330	WP_226316716.1	competence type IV pilus minor pilin ComGG	-
ELZ51_RS00885 (NCTC4669_00187)	comGH	133972..134925 (+)	954	WP_126425653.1	class I SAM-dependent methyltransferase	Machinery gene
ELZ51_RS00890 (NCTC4669_00188)	-	134984..136180 (+)	1197	WP_003049273.1	acetate kinase	-
ELZ51_RS00895 (NCTC4669_00189)	-	136490..136696 (+)	207	WP_003049274.1	helix-turn-helix transcriptional regulator	-
ELZ51_RS00900 (NCTC4669_00190)	-	136744..137058 (+)	315	Protein_131	CPBP family intramembrane glutamic endopeptidase	-
ELZ51_RS11215 (NCTC4669_00191)	-	137076..137513 (+)	438	WP_003049278.1	hypothetical protein	-
ELZ51_RS00910 (NCTC4669_00192)	proC	137652..138428 (-)	777	WP_003049280.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 17006.57 Da
• Isoelectric Point: 10.5665

>NTDB_id=997702 ELZ51_RS00875 WP_003049266.1 133117..133557(+) (comGF) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTNHDQDHWLLFSQQLREELSGVRFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=997702 ELZ51_RS00875 WP_003049266.1 133117..133557(+) (comGF) [Streptococcus dysgalactiae subsp. dysgalactiae strain NCTC4669]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTGATTGCCTTGCTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGGTTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAACCATGATCAAGACCATTGGCTTT
TATTCTCCCAGCAGCTACGAGAAGAGTTAAGTGGAGTGCGATTTCACAAAGTAGAAAACAATAAATTATATATTGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGTCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.482	95.205	0.452
comGF	Streptococcus mutans UA140	46.763	95.205	0.445
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411