Detailed information NTG0997456

Bioinformatically predicted

Overview

• Name: comA
• Type: Regulator
• Locus tag: ABC804_RS10620
• Genome accession: NZ_CP155536
• Coordinates: 2021292..2023445 (-)
• Length: 717 a.a.
• NCBI ID: WP_000668304.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain M264-3
• Function: processing and transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 2016292..2028445

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC804_RS10605 (ABC804_10615)	-	2018908..2019051 (-)	144	WP_050167432.1	hypothetical protein	-
ABC804_RS10610 (ABC804_10620)	purC	2019053..2019760 (-)	708	WP_000043304.1	phosphoribosylaminoimidazolesuccinocarboxamide synthase	-
ABC804_RS10615 (ABC804_10625)	comB	2019930..2021279 (-)	1350	WP_000801618.1	competence pheromone export protein ComB	Regulator
ABC804_RS10620 (ABC804_10630)	comA	2021292..2023445 (-)	2154	WP_000668304.1	peptide cleavage/export ABC transporter ComA	Regulator
ABC804_RS10625 (ABC804_10635)	-	2024032..2024157 (-)	126	WP_000346297.1	PncF family bacteriocin immunity protein	-
ABC804_RS10630 (ABC804_10640)	blpU	2024160..2024390 (-)	231	Protein_2052	bacteriocin-like peptide BlpU	-
ABC804_RS10635 (ABC804_10645)	-	2024593..2024884 (-)	292	Protein_2053	IS5/IS1182 family transposase	-
ABC804_RS10640 (ABC804_10650)	-	2024930..2025163 (-)	234	WP_000659556.1	acyl carrier protein	-
ABC804_RS10645 (ABC804_10655)	plsX	2025169..2026161 (-)	993	WP_000717457.1	phosphate acyltransferase PlsX	-
ABC804_RS10650 (ABC804_10660)	recO	2026158..2026928 (-)	771	WP_000616162.1	DNA repair protein RecO	-
ABC804_RS10655 (ABC804_10665)	-	2026925..2028094 (-)	1170	WP_000366345.1	pyridoxal phosphate-dependent aminotransferase	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80436.52 Da
• Isoelectric Point: 6.2593

>NTDB_id=997456 ABC804_RS10620 WP_000668304.1 2021292..2023445(-) (comA) [Streptococcus pneumoniae strain M264-3]
MKFGKRHYRPQVDQMDCGVASLAMVFGYYGSYYFLAHLRELAKTTMDGTTALGLVKVAEEIGFETRAIKADMTLFDLPDL
TFPFVAHVLKEGKLLHYYVVTGQDKDSIHIADPDPGVKLTKLPRERFEEEWTGVTLFMAPSPDYKPYKEQKNGLLSFIPI
LVKQRGLIANIVLATLLVTVINIVGSYYLQSIIDTYVPDQMRSTLGIISIGLVIVYILQQILSYAQEYLLLVLGQRLSID
VILSYIKHVFHLPMSFFATRRTGEIVSRFTDANSIIDALASTILSIFLDVSTVVIISLVLFSQNTNLFFMTLLALPIYTV
IIFAFMKPFEKMNRDTMEANAVLSSSIIEDINGIETIKSLTSESQRYQKIDKEFVDYLKKSFTYSRAESQQKALKKVAHL
LLNVGILWMGAVLVMDGKMSLGQLITYNTLLVYFTNPLENIINLQTKLQTAQVANNRLNEVYLVASEFEEKKTVEDLSLM
KGEMTFKQVHYKYGYGRDVLSDINLTVPQGSKVAFVGISGSGKTTLAKMMVNFYDPSQGEISLGGVNLNQIDKKALRQYI
NYLPQQPYVFNGTILENLLLGAKEGTTQEDILRAVELVEIREDIERMPLNYQTELTSDGAGISGGQRQRIALARALLTDA
PVLILDEATSSLDILTEKRIVDNLMALDKTLIFIAHRLTIAERTEKVVVLDQGKIVEEGKHADLLAQGGFYAHLVNS

Nucleotide

• Length: 2154 bp

>NTDB_id=997456 ABC804_RS10620 WP_000668304.1 2021292..2023445(-) (comA) [Streptococcus pneumoniae strain M264-3]
ATGAAATTTGGGAAACGTCACTATCGTCCGCAAGTGGATCAGATGGACTGCGGTGTAGCTTCATTAGCCATGGTTTTTGG
CTACTATGGTAGTTATTATTTTTTGGCTCACTTGCGAGAATTGGCTAAGACGACCATGGATGGGACGACGGCTTTGGGCT
TGGTCAAGGTGGCAGAGGAGATTGGTTTTGAGACGCGAGCCATTAAGGCGGATATGACGCTTTTTGACTTGCCGGATTTG
ACTTTTCCTTTTGTTGCCCATGTGCTTAAGGAAGGGAAATTGCTCCACTACTATGTGGTGACTGGGCAGGATAAGGATAG
CATTCATATTGCCGATCCAGATCCCGGGGTGAAGTTGACTAAACTGCCACGTGAGCGTTTTGAGGAAGAATGGACAGGAG
TGACTCTTTTTATGGCACCTAGTCCAGACTATAAGCCTTATAAGGAACAAAAAAATGGTCTGCTCTCTTTTATCCCTATA
TTAGTGAAGCAGCGTGGCTTGATTGCCAATATCGTTTTGGCAACACTCTTGGTAACCGTGATTAACATTGTGGGTTCTTA
TTATCTGCAGTCTATCATTGATACCTATGTGCCAGATCAGATGCGTTCGACACTAGGGATTATTTCTATTGGGCTAGTCA
TCGTCTACATCCTCCAGCAAATCTTGTCTTACGCTCAGGAGTATCTCTTGCTTGTTTTGGGGCAACGCTTGTCGATTGAC
GTGATTTTGTCCTATATCAAGCATGTTTTTCACCTCCCTATGTCCTTTTTCGCGACACGCAGGACAGGGGAAATTGTGTC
TCGTTTCACGGATGCTAACAGTATTATCGATGCGCTGGCTTCGACCATTCTTTCGATTTTCCTAGATGTGTCAACAGTTG
TCATTATTTCCCTTGTTTTATTTTCACAAAATACCAATCTCTTTTTCATGACTTTATTGGCGCTTCCTATCTACACAGTG
ATTATCTTTGCCTTTATGAAGCCGTTTGAAAAGATGAATCGGGACACCATGGAAGCCAATGCGGTTCTGTCTTCTTCTAT
CATTGAGGACATCAACGGTATTGAGACTATCAAGTCCTTGACCAGTGAAAGTCAGCGTTACCAAAAAATTGACAAGGAAT
TTGTGGATTATCTGAAGAAATCCTTTACCTATAGTCGAGCAGAGAGTCAGCAAAAGGCTCTGAAAAAGGTTGCCCATCTC
TTACTTAATGTCGGCATTCTCTGGATGGGGGCTGTTCTGGTCATGGATGGCAAGATGAGTTTGGGGCAGTTGATTACCTA
TAATACCTTGCTGGTTTACTTTACCAATCCTTTGGAAAATATCATCAATCTGCAAACCAAGCTTCAGACAGCGCAGGTTG
CCAATAACCGTCTAAATGAAGTGTATCTAGTAGCTTCTGAGTTTGAGGAGAAGAAAACAGTTGAGGATTTGAGCTTGATG
AAGGGAGAGATGACTTTCAAGCAGGTTCATTACAAGTATGGCTATGGTCGAGACGTCTTGTCGGATATCAATTTAACCGT
TCCCCAAGGGTCTAAGGTGGCTTTTGTGGGGATTTCAGGGTCAGGTAAGACGACTTTGGCCAAGATGATGGTTAATTTTT
ACGACCCAAGTCAAGGGGAGATTAGTCTGGGTGGTGTCAATCTCAATCAGATTGATAAAAAAGCCCTACGCCAGTACATC
AACTATCTGCCTCAACAGCCCTATGTCTTTAACGGAACGATTTTGGAGAATCTTCTTTTGGGAGCCAAGGAGGGGACGAC
ACAGGAAGATATCTTACGGGCGGTCGAATTGGTAGAGATTCGAGAGGATATCGAGCGCATGCCACTGAATTACCAGACAG
AATTGACTTCGGATGGGGCAGGGATTTCAGGTGGTCAACGTCAGAGAATCGCTTTGGCGCGTGCTCTCTTGACAGATGCG
CCGGTCTTGATTTTGGATGAGGCGACTAGCAGTTTGGATATTTTGACAGAGAAGCGGATTGTCGATAATCTCATGGCTTT
GGACAAGACCTTGATTTTCATTGCTCACCGCTTGACTATTGCTGAGCGGACAGAGAAGGTGGTTGTCTTGGATCAGGGCA
AGATTGTCGAAGAAGGAAAGCATGCTGATTTGCTTGCACAGGGTGGCTTTTACGCCCATTTGGTCAATAGCTAG

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-650)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Streptococcus pneumoniae Rx1	99.442	100	0.994
comA	Streptococcus pneumoniae D39	99.442	100	0.994
comA	Streptococcus pneumoniae R6	99.442	100	0.994
comA	Streptococcus pneumoniae TIGR4	99.024	100	0.99
comA	Streptococcus mitis SK321	98.466	100	0.985
comA	Streptococcus mitis NCTC 12261	98.187	100	0.982
comA	Streptococcus gordonii str. Challis substr. CH1	80.474	100	0.805
comA/nlmT	Streptococcus mutans UA159	64.435	100	0.644