Detailed information NTG0997082

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: ABC810_RS01065
• Genome accession: NZ_CP155532
• Coordinates: 214922..215224 (+)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain SP264
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 209922..220224

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABC810_RS01035 (ABC810_01035)	-	210679..211737 (+)	1059	WP_000649468.1	zinc-dependent alcohol dehydrogenase family protein	-
ABC810_RS01040 (ABC810_01040)	-	211888..212253 (+)	366	WP_000286415.1	DUF1033 family protein	-
ABC810_RS01045 (ABC810_01045)	comGA/cglA/cilD	212329..213270 (+)	942	WP_000249573.1	competence type IV pilus ATPase ComGA	Machinery gene
ABC810_RS01050 (ABC810_01050)	comGB/cglB	213218..214234 (+)	1017	WP_078134418.1	competence type IV pilus assembly protein ComGB	Machinery gene
ABC810_RS01055 (ABC810_01055)	comGC/cglC	214236..214562 (+)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
ABC810_RS01060 (ABC810_01060)	comGD/cglD	214555..214959 (+)	405	WP_000588030.1	competence type IV pilus minor pilin ComGD	Machinery gene
ABC810_RS01065 (ABC810_01065)	comGE/cglE	214922..215224 (+)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
ABC810_RS01070 (ABC810_01070)	comGF/cglF	215187..215648 (+)	462	WP_000250539.1	competence type IV pilus minor pilin ComGF	Machinery gene
ABC810_RS01075 (ABC810_01075)	comGG/cglG	215626..216072 (+)	447	WP_001811371.1	competence type IV pilus minor pilin ComGG	Machinery gene
ABC810_RS01080 (ABC810_01080)	-	216175..216769 (+)	595	Protein_196	methyltransferase domain-containing protein	-
ABC810_RS01085 (ABC810_01085)	comYH	216830..217783 (+)	954	WP_000345133.1	class I SAM-dependent methyltransferase	Machinery gene
ABC810_RS01090 (ABC810_01090)	-	217834..219024 (+)	1191	WP_000167766.1	acetate kinase	-
ABC810_RS01095 (ABC810_01095)	-	219025..219156 (+)	132	WP_000768904.1	hypothetical protein	-
ABC810_RS01100 (ABC810_01100)	rnpA	219173..219544 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=997082 ABC810_RS01065 WP_000413382.1 214922..215224(+) (comGE/cglE) [Streptococcus pneumoniae strain SP264]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=997082 ABC810_RS01065 WP_000413382.1 214922..215224(+) (comGE/cglE) [Streptococcus pneumoniae strain SP264]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4