Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   ABC810_RS01085 Genome accession   NZ_CP155532
Coordinates   216830..217783 (+) Length   317 a.a.
NCBI ID   WP_000345133.1    Uniprot ID   A0A0T8FEM8
Organism   Streptococcus pneumoniae strain SP264     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 211830..222783
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABC810_RS01040 (ABC810_01040) - 211888..212253 (+) 366 WP_000286415.1 DUF1033 family protein -
  ABC810_RS01045 (ABC810_01045) comGA/cglA/cilD 212329..213270 (+) 942 WP_000249573.1 competence type IV pilus ATPase ComGA Machinery gene
  ABC810_RS01050 (ABC810_01050) comGB/cglB 213218..214234 (+) 1017 WP_078134418.1 competence type IV pilus assembly protein ComGB Machinery gene
  ABC810_RS01055 (ABC810_01055) comGC/cglC 214236..214562 (+) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  ABC810_RS01060 (ABC810_01060) comGD/cglD 214555..214959 (+) 405 WP_000588030.1 competence type IV pilus minor pilin ComGD Machinery gene
  ABC810_RS01065 (ABC810_01065) comGE/cglE 214922..215224 (+) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  ABC810_RS01070 (ABC810_01070) comGF/cglF 215187..215648 (+) 462 WP_000250539.1 competence type IV pilus minor pilin ComGF Machinery gene
  ABC810_RS01075 (ABC810_01075) comGG/cglG 215626..216072 (+) 447 WP_001811371.1 competence type IV pilus minor pilin ComGG Machinery gene
  ABC810_RS01080 (ABC810_01080) - 216175..216769 (+) 595 Protein_196 methyltransferase domain-containing protein -
  ABC810_RS01085 (ABC810_01085) comYH 216830..217783 (+) 954 WP_000345133.1 class I SAM-dependent methyltransferase Machinery gene
  ABC810_RS01090 (ABC810_01090) - 217834..219024 (+) 1191 WP_000167766.1 acetate kinase -
  ABC810_RS01095 (ABC810_01095) - 219025..219156 (+) 132 WP_000768904.1 hypothetical protein -
  ABC810_RS01100 (ABC810_01100) rnpA 219173..219544 (+) 372 WP_000739246.1 ribonuclease P protein component -
  ABC810_RS01105 (ABC810_01105) - 219519..220343 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  ABC810_RS01110 (ABC810_01110) jag 220362..221348 (+) 987 WP_000260018.1 RNA-binding cell elongation regulator Jag/EloR -
  ABC810_RS01115 (ABC810_01115) - 221399..222022 (+) 624 WP_000932661.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35721.90 Da        Isoelectric Point: 4.2665

>NTDB_id=997085 ABC810_RS01085 WP_000345133.1 216830..217783(+) (comYH) [Streptococcus pneumoniae strain SP264]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=997085 ABC810_RS01085 WP_000345133.1 216830..217783(+) (comYH) [Streptococcus pneumoniae strain SP264]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGTTAAACCAGGTCAAAGACAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCTCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTTTACCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0T8FEM8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment