Detailed information    

insolico Bioinformatically predicted

Overview

Name   comW   Type   Regulator
Locus tag   AAYT22_RS00115 Genome accession   NZ_CP154876
Coordinates   22172..22408 (+) Length   78 a.a.
NCBI ID   WP_000939546.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 20155336     
Function   stabilization and activation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 17172..27408
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAYT22_RS00105 (AAYT22_00105) - 20225..21075 (+) 851 Protein_14 IS630 family transposase -
  AAYT22_RS00110 (AAYT22_00110) - 21110..21907 (-) 798 Protein_15 transposase -
  AAYT22_RS00115 (AAYT22_00115) comW 22172..22408 (+) 237 WP_000939546.1 sigma(X)-activator ComW Regulator
  AAYT22_RS00120 (AAYT22_00120) - 22639..23925 (+) 1287 WP_001819018.1 adenylosuccinate synthase -
  AAYT22_RS00125 (AAYT22_00125) tadA 24126..24593 (+) 468 WP_000291875.1 tRNA adenosine(34) deaminase TadA -
  AAYT22_RS00135 (AAYT22_00135) - 24780..25223 (+) 444 WP_000701974.1 dUTP diphosphatase -
  AAYT22_RS00140 (AAYT22_00140) - 25225..25740 (+) 516 WP_000691236.1 histidine phosphatase family protein -
  AAYT22_RS00145 (AAYT22_00145) radA 25754..27115 (+) 1362 WP_078143130.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 78 a.a.        Molecular weight: 9686.14 Da        Isoelectric Point: 6.7051

>NTDB_id=994344 AAYT22_RS00115 WP_000939546.1 22172..22408(+) (comW) [Streptococcus pneumoniae strain 20155336]
MLQKIYEQMANFYDSIEEEYGPTFGDNFDWEHVHFKFLIYYLVRYGIGCRRDFIVYHYRVAYRLYLEKLVMNRGFISC

Nucleotide


Download         Length: 237 bp        

>NTDB_id=994344 AAYT22_RS00115 WP_000939546.1 22172..22408(+) (comW) [Streptococcus pneumoniae strain 20155336]
ATGTTACAAAAAATTTATGAGCAGATGGCTAATTTCTATGATAGTATTGAAGAAGAGTATGGTCCTACATTTGGTGATAA
TTTTGACTGGGAACATGTTCATTTTAAATTTTTAATTTATTATTTAGTGAGATATGGCATTGGTTGTCGTAGGGATTTTA
TCGTTTACCATTATCGTGTTGCTTATCGTTTGTATCTTGAAAAATTGGTAATGAATCGGGGTTTTATTTCTTGTTGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comW Streptococcus pneumoniae Rx1

98.718

100

0.987
  comW Streptococcus pneumoniae D39

98.718

100

0.987
  comW Streptococcus pneumoniae R6

98.718

100

0.987
  comW Streptococcus pneumoniae TIGR4

98.718

100

0.987
  comW Streptococcus mitis SK321

76.923

100

0.769
  comW Streptococcus mitis NCTC 12261

76.623

98.718

0.756

Multiple sequence alignment