Detailed information NTG0993677

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: AAIS09_RS04395
• Genome accession: NZ_CP154595
• Coordinates: 857205..859445 (+)
• Length: 746 a.a.
• NCBI ID: WP_061813580.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain serotype 4
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 852205..864445

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAIS09_RS04365 (AAIS09_04350)	-	852355..853323 (+)	969	WP_000658191.1	PhoH family protein	-
AAIS09_RS04370 (AAIS09_04355)	-	853516..854016 (+)	501	WP_001866231.1	GNAT family N-acetyltransferase	-
AAIS09_RS04375 (AAIS09_04360)	-	854019..854345 (+)	327	Protein_860	TfoX/Sxy family protein	-
AAIS09_RS04380 (AAIS09_04365)	ald	854646..855757 (-)	1112	Protein_861	alanine dehydrogenase	-
AAIS09_RS04385 (AAIS09_04370)	-	855934..856503 (+)	570	WP_061813581.1	GNAT family N-acetyltransferase	-
AAIS09_RS04390 (AAIS09_04375)	comEA/celA/cilE	856571..857221 (+)	651	WP_057546897.1	ComEA family DNA-binding protein	Machinery gene
AAIS09_RS04395 (AAIS09_04380)	comEC/celB	857205..859445 (+)	2241	WP_061813580.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
AAIS09_RS04400 (AAIS09_04385)	-	859624..859812 (+)	189	WP_061813579.1	hypothetical protein	-
AAIS09_RS04405 (AAIS09_04390)	-	859845..860432 (+)	588	WP_000939895.1	ATP-binding cassette domain-containing protein	-
AAIS09_RS04410 (AAIS09_04395)	-	860436..861620 (+)	1185	WP_061813578.1	hypothetical protein	-
AAIS09_RS04415 (AAIS09_04400)	infC	861931..862461 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
AAIS09_RS04420 (AAIS09_04405)	rpmI	862494..862694 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
AAIS09_RS04425 (AAIS09_04410)	rplT	862746..863105 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
AAIS09_RS04430 (AAIS09_04415)	-	863163..863543 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84471.92 Da
• Isoelectric Point: 9.5017

>NTDB_id=993677 AAIS09_RS04395 WP_061813580.1 857205..859445(+) (comEC/celB) [Streptococcus pneumoniae strain serotype 4]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLQLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVARRPLVFGQPNAWLLILLLISLALVYDLRKNIKGLTVLSLLITGLFFLTK
YPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
ENVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQATQTKMRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQQGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGLDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=993677 AAIS09_RS04395 WP_061813580.1 857205..859445(+) (comEC/celB) [Streptococcus pneumoniae strain serotype 4]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGCATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCAATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGTGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTAGAGGGCATTATTCGCTTGGT
CTCGCAGGTGGCAAGGAGACCGCTTGTCTTTGGTCAACCCAACGCATGGCTTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAGGATTAACAGTATTGAGTTTATTGATTACAGGTCTCTTTTTCCTTACCAAG
TATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGAATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGGCGACTCAAACAAAGATGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGATACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCTAGCCAACAAGGAAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGGTTTAAGGGGTTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Competence protein (Competence) (216-458)

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	98.928	100	0.989
comEC/celB	Streptococcus pneumoniae Rx1	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae D39	96.783	100	0.968
comEC/celB	Streptococcus pneumoniae R6	96.783	100	0.968
comEC/celB	Streptococcus mitis SK321	92.091	100	0.921
comEC/celB	Streptococcus mitis NCTC 12261	91.946	99.866	0.918
comEC	Lactococcus lactis subsp. cremoris KW2	43.995	99.33	0.437