Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ACKTXI_RS31670 Genome accession   NZ_AP035884
Coordinates   7073192..7073812 (-) Length   206 a.a.
NCBI ID   WP_030633275.1    Uniprot ID   -
Organism   Streptomyces sp. CMC78     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 7068192..7078812
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACKTXI_RS31650 (SCMC78_63960) - 7068760..7069989 (-) 1230 WP_218784736.1 DUF349 domain-containing protein -
  ACKTXI_RS31655 (SCMC78_63970) - 7070216..7071007 (-) 792 WP_030085939.1 peptidylprolyl isomerase -
  ACKTXI_RS31660 (SCMC78_63980) - 7071157..7071846 (+) 690 WP_319598893.1 MBL fold metallo-hydrolase -
  ACKTXI_RS31665 (SCMC78_63990) hisS 7071864..7073126 (+) 1263 WP_319598894.1 histidine--tRNA ligase -
  ACKTXI_RS31670 (SCMC78_64000) vraR 7073192..7073812 (-) 621 WP_030633275.1 response regulator Regulator
  ACKTXI_RS31675 (SCMC78_64010) - 7073812..7075098 (-) 1287 WP_408054590.1 sensor histidine kinase -
  ACKTXI_RS31680 (SCMC78_64020) - 7075056..7075877 (-) 822 WP_408054591.1 ABC transporter permease -
  ACKTXI_RS31685 (SCMC78_64030) - 7075874..7076731 (-) 858 WP_107058025.1 ABC transporter ATP-binding protein -
  ACKTXI_RS31690 (SCMC78_64040) - 7076868..7077506 (+) 639 WP_030085949.1 vitamin K epoxide reductase family protein -

Sequence

Protein


Download         Length: 206 a.a.        Molecular weight: 21978.44 Da        Isoelectric Point: 5.4035

>NTDB_id=99242 ACKTXI_RS31670 WP_030633275.1 7073192..7073812(-) (vraR) [Streptomyces sp. CMC78]
MIRVLLADDHPVVREGLRGMLDAEPDLEVVAEASSGPRAEALCAELLPDIVLMDLRMPGGGGVESIRRIRAAGLPCRVVV
LTTYESDGDILRAVEAGASGYLLKDLGRAELADAIRAAARGETVLAPTVATRLVDQLREAPEVPRLSERETQVLRLVAEG
CTNAEIGRRLFIGESTVKTHLLRVFGKLGVGDRTAAVTGAMRHGLL

Nucleotide


Download         Length: 621 bp        

>NTDB_id=99242 ACKTXI_RS31670 WP_030633275.1 7073192..7073812(-) (vraR) [Streptomyces sp. CMC78]
ATGATCCGAGTCCTGCTGGCCGACGACCACCCCGTCGTACGGGAGGGGCTGCGCGGGATGCTGGACGCCGAGCCGGACCT
GGAGGTCGTGGCCGAGGCGTCCAGCGGTCCGCGCGCCGAGGCGCTCTGCGCCGAACTGCTGCCGGACATCGTGCTGATGG
ACCTGCGGATGCCGGGCGGCGGGGGCGTCGAGTCGATCCGCCGGATCCGTGCGGCCGGGCTGCCGTGCCGGGTCGTCGTG
CTCACCACGTACGAGAGCGACGGCGACATCCTGCGCGCGGTGGAGGCCGGCGCGTCCGGTTATCTGCTCAAGGACCTGGG
CCGGGCGGAGCTGGCGGACGCGATCCGGGCCGCGGCCCGGGGCGAGACCGTGCTCGCGCCGACGGTGGCGACCCGGCTGG
TGGACCAGTTGCGCGAAGCGCCGGAGGTGCCCCGGCTCTCGGAGCGCGAGACGCAGGTGCTGCGGCTGGTGGCGGAGGGG
TGCACCAACGCGGAGATCGGGCGGCGGCTGTTCATCGGCGAGTCGACGGTGAAGACCCATCTGCTGCGGGTCTTCGGCAA
GCTGGGCGTCGGCGACCGGACCGCCGCGGTGACGGGGGCGATGCGCCACGGGCTGCTGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(146-198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.806

100

0.398
  letA Legionella pneumophila str. Paris

37.799

100

0.383
  letA Legionella pneumophila strain ERS1305867

37.799

100

0.383
  degU Bacillus subtilis subsp. subtilis str. 168

34.529

100

0.374

Multiple sequence alignment