Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   SP4011_RS10760 Genome accession   NZ_AP026968
Coordinates   2154485..2155234 (-) Length   249 a.a.
NCBI ID   WP_173249820.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2149485..2160234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS10745 (SP4011_20750) - 2151482..2152843 (+) 1362 WP_338619305.1 bacteriocin secretion accessory protein -
  SP4011_RS10750 (SP4011_20760) blpC 2152900..2153040 (+) 141 WP_112444774.1 quorum-sensing system pheromone BlpC -
  SP4011_RS10755 (SP4011_20770) - 2153147..2154481 (-) 1335 WP_338619307.1 sensor histidine kinase -
  SP4011_RS10760 (SP4011_20780) comE/blpR 2154485..2155234 (-) 750 WP_173249820.1 response regulator transcription factor Regulator
  SP4011_RS10765 (SP4011_20790) - 2155231..2155578 (-) 348 WP_112444768.1 LytTR family DNA-binding domain-containing protein -
  SP4011_RS10770 (SP4011_20800) - 2155762..2156148 (+) 387 WP_225904702.1 hypothetical protein -
  SP4011_RS10775 (SP4011_20810) - 2156294..2157772 (-) 1479 WP_338619309.1 ABC transporter substrate-binding protein -
  SP4011_RS10780 (SP4011_20820) - 2157876..2158799 (-) 924 WP_000818348.1 carbohydrate ABC transporter permease -
  SP4011_RS10785 (SP4011_20830) - 2158813..2159742 (-) 930 WP_049552653.1 ABC transporter permease -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29243.80 Da        Isoelectric Point: 6.0966

>NTDB_id=99142 SP4011_RS10760 WP_173249820.1 2154485..2155234(-) (comE/blpR) [Streptococcus parapneumoniae strain SP4011]
MNIFILEDDFIQQTRMENLVYDILEKNCWEVKHCGVYGKPNQLLEDMMERGGHQLFFLDIEIKNDVRKGLDIALEIRDRD
PNAVIVFVTTHSEFMPVSFQYQVSALDFIDKELPESSFRERVEKAIAYVHKNKHQLMTEDSFVFTNSKALVQVPFSDLLY
IETSMIPHKLVLYSMRERIEFYGKISDILKQEPRLVQCHRSFIVNPYNISSIDKEEKLVYLKNGSSCLVSRLKMRALLNI
VKDLHDSKE

Nucleotide


Download         Length: 750 bp        

>NTDB_id=99142 SP4011_RS10760 WP_173249820.1 2154485..2155234(-) (comE/blpR) [Streptococcus parapneumoniae strain SP4011]
ATGAATATCTTTATATTAGAGGATGATTTTATACAGCAGACTAGGATGGAAAATCTGGTGTATGATATTTTAGAGAAGAA
TTGTTGGGAAGTAAAGCACTGTGGTGTTTATGGTAAACCGAATCAATTGTTAGAAGATATGATGGAACGTGGAGGTCATC
AACTTTTCTTTTTGGATATTGAAATTAAAAACGATGTTAGAAAAGGGTTAGATATTGCTTTGGAAATCAGAGATAGAGAT
CCAAATGCAGTCATTGTTTTTGTAACAACTCATTCAGAATTTATGCCTGTTAGTTTTCAATATCAAGTATCAGCTTTAGA
TTTTATTGATAAGGAATTGCCTGAAAGCTCTTTTAGGGAACGTGTGGAAAAGGCAATCGCTTATGTTCACAAGAATAAAC
ATCAACTAATGACTGAAGATTCTTTTGTGTTTACAAATTCTAAAGCACTCGTTCAGGTTCCATTTTCGGATTTGCTTTAT
ATAGAAACGTCAATGATTCCTCATAAGCTAGTTCTTTATTCTATGAGAGAAAGAATAGAATTTTACGGTAAAATTTCTGA
TATATTGAAGCAAGAACCCAGATTGGTTCAGTGTCATCGTTCTTTTATTGTGAATCCTTATAATATCTCTTCAATAGATA
AGGAAGAAAAACTAGTCTATTTGAAGAACGGGTCAAGTTGCCTAGTATCTAGGTTAAAAATGAGGGCATTGCTGAATATA
GTTAAAGATTTACATGATAGTAAGGAGTAG

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(150-240)

Response regulator receiver domain (Response_reg)

(3-122)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

51.406

100

0.514
  comE/comE1 Streptococcus equinus JB1

41.597

95.582

0.398
  comE/comE2 Streptococcus gordonii strain NCTC7865

39.431

98.795

0.39
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

39.431

98.795

0.39
  comE/comE2 Streptococcus equinus JB1

37.705

97.992

0.369

Multiple sequence alignment