Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP   Type   Regulator
Locus tag   SP4011_RS02795 Genome accession   NZ_AP026968
Coordinates   509577..511478 (+) Length   633 a.a.
NCBI ID   WP_338619763.1    Uniprot ID   -
Organism   Streptococcus parapneumoniae strain SP4011     
Function   require for competence development; phosphorylate ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 504577..516478
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP4011_RS02780 (SP4011_04910) fmt 506584..507519 (+) 936 WP_261060990.1 methionyl-tRNA formyltransferase -
  SP4011_RS02785 (SP4011_04920) rsmB 507512..508825 (+) 1314 WP_338619762.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  SP4011_RS02790 (SP4011_04930) - 508840..509580 (+) 741 WP_050234902.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  SP4011_RS02795 (SP4011_04940) stkP 509577..511478 (+) 1902 WP_338619763.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SP4011_RS02800 (SP4011_04950) - 511567..512325 (+) 759 WP_057487162.1 threonine/serine exporter family protein -
  SP4011_RS02805 (SP4011_04960) - 512327..512776 (+) 450 WP_057487161.1 threonine/serine exporter family protein -
  SP4011_RS02810 (SP4011_04970) - 512935..513183 (+) 249 WP_057487170.1 hypothetical protein -
  SP4011_RS02815 (SP4011_04980) - 513314..514486 (+) 1173 WP_050252772.1 hydroxymethylglutaryl-CoA synthase -
  SP4011_RS02820 (SP4011_04990) - 514486..515760 (+) 1275 WP_218764351.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 633 a.a.        Molecular weight: 69100.59 Da        Isoelectric Point: 9.3807

>NTDB_id=99104 SP4011_RS02795 WP_338619763.1 509577..511478(+) (stkP) [Streptococcus parapneumoniae strain SP4011]
MIQIGKIFAGRYRIVKQIGRGGMADVYLAKDLILDGEEVAVKVLRTNYQTDPIAVARFQREARAMADLDHPHIVRITDIG
EEDGQQYLAMEYVAGLDLKRYIKEHYPLSNEEAVRIMGQILLAMRLAHTRGIVHRDLKPQNILLTPDGTVKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATVQSDIYAMGIIFYEMLTGHIPYDGDSAVTIALQHFQKPLPSVIAENPSVP
QALENVVIKATAKKLTDRYKSVAEMYVDLSSSLSYNRRNEPKLVFDDATKADTKTLPKVSQSTLTSIPKVQAQTEHKPIK
KTSQAVTEETYQPQAPKKRRFKMRYLIFLASIVLVAASLIWILSRTPATISIPDVAGQTVAEAKETLKKANFEIGEEKSE
ASEKVEEGRIIRTDPGAGTGRKEGTKINLVVSSGKQSFQISNYVGRKSTDVIAELKQKKVPENLIKIEEEESSESEAGTV
LRQSPAAGTTYDLSKASTITLTVAKKVTSVAMPSYIGSSLEFTKNNLVQIVGIKEANIEVVEVSTAPAGTAEGTVVEQSP
KAGEKVDLTKTRVKISIYKPKTPPSTSSSAPAQRGNQGSTTTPSQGNQQGNQRENAPGPTQSSSEGNHENSRD

Nucleotide


Download         Length: 1902 bp        

>NTDB_id=99104 SP4011_RS02795 WP_338619763.1 509577..511478(+) (stkP) [Streptococcus parapneumoniae strain SP4011]
ATGATCCAAATCGGCAAGATTTTTGCCGGACGCTATCGGATTGTCAAACAGATTGGTCGAGGAGGCATGGCGGATGTCTA
CCTAGCCAAAGACTTAATCTTAGATGGGGAAGAAGTGGCAGTGAAGGTTCTGAGAACCAACTACCAGACGGACCCGATAG
CTGTAGCTCGTTTTCAGCGTGAAGCGAGAGCTATGGCAGATTTAGACCATCCTCATATCGTTCGGATAACAGATATTGGC
GAGGAAGACGGTCAACAGTATCTTGCAATGGAGTATGTTGCTGGACTAGACCTCAAACGCTATATCAAGGAACATTATCC
TCTTTCTAATGAAGAAGCCGTCCGTATCATGGGACAAATCCTCCTAGCCATGCGTTTGGCCCATACCAGAGGAATTGTTC
ACCGGGACTTGAAACCTCAAAACATTCTTTTGACACCAGATGGGACTGTCAAGGTTACAGACTTTGGGATTGCAGTAGCC
TTTGCTGAGACGAGTCTGACTCAGACTAACTCGATGCTGGGTTCAGTTCATTACTTGTCACCAGAGCAGGCGCGTGGTTC
GAAGGCGACTGTACAAAGTGATATCTATGCAATGGGGATTATTTTCTATGAGATGCTGACAGGTCATATCCCTTATGATG
GGGATAGTGCAGTGACTATCGCCCTCCAGCATTTCCAAAAGCCCCTGCCGTCCGTTATTGCTGAGAATCCATCTGTGCCT
CAGGCTTTGGAGAATGTTGTTATCAAGGCAACTGCTAAGAAATTGACAGATCGCTATAAATCAGTTGCTGAAATGTATGT
GGATTTGTCTAGTAGTTTGTCTTATAATCGTCGCAATGAACCAAAGCTGGTCTTTGATGATGCGACTAAGGCGGACACCA
AGACTCTACCAAAAGTATCCCAGAGCACCTTGACTTCGATTCCTAAGGTTCAAGCGCAGACAGAACACAAACCAATCAAA
AAAACAAGTCAGGCTGTGACAGAGGAAACTTACCAACCACAAGCACCGAAAAAACGTAGATTTAAGATGCGTTACCTGAT
TTTTTTGGCCAGCATTGTATTGGTGGCAGCTTCTCTTATTTGGATACTATCCAGAACTCCTGCAACCATTTCTATTCCAG
ATGTGGCAGGTCAGACAGTTGCGGAAGCCAAGGAAACGCTCAAAAAAGCCAATTTTGAGATTGGCGAGGAGAAGTCAGAG
GCTAGTGAAAAGGTGGAAGAAGGGCGGATTATCCGTACAGATCCTGGTGCTGGAACTGGTCGAAAAGAAGGAACGAAAAT
CAATTTGGTTGTCTCATCAGGCAAACAATCCTTCCAAATTAGTAATTATGTCGGCCGGAAATCGACAGATGTTATAGCAG
AACTCAAGCAGAAGAAGGTTCCTGAAAATCTCATCAAAATTGAGGAAGAAGAATCAAGTGAGAGCGAAGCAGGAACTGTT
CTCAGACAGAGTCCAGCTGCTGGAACAACCTATGATTTGAGCAAGGCCTCAACGATTACCTTAACCGTTGCTAAGAAAGT
AACCAGCGTTGCTATGCCAAGTTATATAGGATCTAGTCTCGAATTTACTAAAAATAATCTCGTTCAAATTGTCGGTATTA
AAGAAGCCAATATTGAAGTTGTAGAAGTGTCGACAGCTCCCGCTGGAACTGCTGAAGGTACAGTCGTTGAACAGAGTCCA
AAAGCAGGTGAAAAGGTTGATTTGACTAAGACGCGTGTCAAGATTTCAATCTACAAACCAAAAACACCGCCGTCAACGTC
ATCATCAGCACCAGCCCAACGTGGAAACCAAGGTTCTACTACAACACCAAGTCAGGGGAACCAACAAGGAAATCAACGAG
AGAATGCACCTGGTCCTACTCAATCAAGTAGTGAAGGCAACCACGAAAATTCTCGTGATTAA

Domains

Predicted by InterproScan.

PASTA domain (PASTA)

(440-505)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(372-432)

Protein kinase domain (Pkinase)

(12-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP Streptococcus pneumoniae TIGR4

84.642

92.575

0.784
  stkP Streptococcus pneumoniae D39

84.3

92.575

0.78
  stkP Streptococcus pneumoniae R6

84.3

92.575

0.78
  stkP Streptococcus pneumoniae Rx1

84.13

92.575

0.779
  pknB Streptococcus mutans UA159

55.286

91.153

0.504
  stkP/pknB Streptococcus salivarius strain HSISS4

53.547

93.523

0.501

Multiple sequence alignment