Detailed information NTG0099101

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: SP4011_RS02160
• Genome accession: NZ_AP026968
• Coordinates: 389897..390964 (+)
• Length: 355 a.a.
• NCBI ID: WP_000159551.1
• Uniprot ID: F9HLV7
• Organism: Streptococcus parapneumoniae strain SP4011
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 384897..395964

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SP4011_RS02145 (SP4011_03640)	amiA3	385420..387399 (+)	1980	WP_262081318.1	peptide ABC transporter substrate-binding protein	Regulator
SP4011_RS02150 (SP4011_03650)	amiC	387466..388962 (+)	1497	WP_077804683.1	ABC transporter permease	Regulator
SP4011_RS02155 (SP4011_03660)	amiD	388962..389888 (+)	927	WP_000103703.1	oligopeptide ABC transporter permease OppC	Regulator
SP4011_RS02160 (SP4011_03670)	amiE	389897..390964 (+)	1068	WP_000159551.1	ABC transporter ATP-binding protein	Regulator
SP4011_RS02165 (SP4011_03680)	amiF	390975..391901 (+)	927	WP_042900321.1	ATP-binding cassette domain-containing protein	Regulator
SP4011_RS02170 (SP4011_03690)	-	392460..393437 (+)	978	WP_000869840.1	ABC transporter substrate-binding protein	-
SP4011_RS02175 (SP4011_03700)	-	393449..394342 (+)	894	WP_338619651.1	ABC transporter permease	-
SP4011_RS02180 (SP4011_03710)	-	394355..395158 (+)	804	WP_000157661.1	ABC transporter ATP-binding protein	-
SP4011_RS02185 (SP4011_03720)	-	395455..395703 (+)	249	WP_000364990.1	YneF family protein	-

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39549.11 Da
• Isoelectric Point: 4.7541

>NTDB_id=99101 SP4011_RS02160 WP_000159551.1 389897..390964(+) (amiE) [Streptococcus parapneumoniae strain SP4011]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFDEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLED

Nucleotide

• Length: 1068 bp

>NTDB_id=99101 SP4011_RS02160 WP_000159551.1 389897..390964(+) (amiE) [Streptococcus parapneumoniae strain SP4011]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTAACAGC
CATTCGTGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGGAAATCTGTTT
TGACAAAGACTTTCACAGGTATGCTTGAAGAAAATGGTCGCATTGCTCAGGGTAGTATTGACTACCGTGGTCAGGATTTG
ACAGCCTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCAATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGGATTCCAGACGCAGATAGACGTTTTGATGAATACCCATTCCAATAT
TCTGGAGGGATGCGTCAACGTATCGTAATTGCTATTGCCCTTGCCTGCCGACCTGATGTCTTAATCTGTGATGAGCCAAC
GACTGCCTTGGATGTGACTATCCAAGCACAGATTATTGATTTGCTCAAATCATTACAAAACGAGTACCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTAGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACTGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCCTTTGCCT
TGCGTTCTGACTATGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCACGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGAAGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: F9HLV7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	87.887	100	0.879
amiE	Streptococcus thermophilus LMG 18311	86.197	100	0.862
amiE	Streptococcus thermophilus LMD-9	86.197	100	0.862
oppD	Streptococcus mutans UA159	54.261	99.155	0.538