Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8570_RS10680 Genome accession   NZ_AP026932
Coordinates   2104899..2105561 (-) Length   220 a.a.
NCBI ID   WP_050263690.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701549     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2099899..2110561
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8570_RS10655 (PC1528_20890) - 2100043..2100309 (-) 267 WP_001278167.1 Veg family protein -
  R8570_RS10660 (PC1528_20900) dnaB 2100311..2101663 (-) 1353 WP_000852486.1 replicative DNA helicase -
  R8570_RS10665 (PC1528_20910) rplI 2101707..2102159 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  R8570_RS10670 (PC1528_20920) - 2102156..2104135 (-) 1980 WP_317647401.1 DHH family phosphoesterase -
  R8570_RS10675 (PC1528_20930) hpf 2104271..2104819 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8570_RS10680 (PC1528_20940) comFC/cflB 2104899..2105561 (-) 663 WP_050263690.1 ComF family protein Machinery gene
  R8570_RS10685 (PC1528_20950) comFA/cflA 2105558..2106856 (-) 1299 WP_050263689.1 DEAD/DEAH box helicase Machinery gene
  R8570_RS10690 (PC1528_20960) - 2106912..2107547 (+) 636 WP_000395739.1 YigZ family protein -
  R8570_RS10695 (PC1528_20970) cysK 2107832..2108752 (+) 921 WP_000029860.1 cysteine synthase A -
  R8570_RS10700 - 2108827..2109365 (-) 539 Protein_2070 transposase -
  R8570_RS10705 (PC1528_20990) - 2109338..2109625 (+) 288 Protein_2071 transposase -
  R8570_RS10710 (PC1528_21000) tnpB 2109816..2110103 (-) 288 WP_000586646.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25251.08 Da        Isoelectric Point: 7.3690

>NTDB_id=98938 R8570_RS10680 WP_050263690.1 2104899..2105561(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900701549]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTRCQDCQLWCKEGVEVSHRAIFTYNQ
AIKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=98938 R8570_RS10680 WP_050263690.1 2104899..2105561(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900701549]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAGGTGTCAAGACTGTCAACTTTGGTGTAAAGAAGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATAAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAACAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae Rx1

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae D39

98.636

100

0.986
  comFC/cflB Streptococcus pneumoniae R6

98.636

100

0.986
  comFC/cflB Streptococcus mitis NCTC 12261

90.909

100

0.909
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment