Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   AAFQ93_RS09130 Genome accession   NZ_CP152419
Coordinates   1915298..1916035 (-) Length   245 a.a.
NCBI ID   WP_375555245.1    Uniprot ID   -
Organism   Streptococcus nidrosiense strain SO-23-1     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1910298..1921035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAFQ93_RS09125 (AAFQ93_09060) - 1914228..1914791 (-) 564 WP_375555244.1 TIGR01440 family protein -
  AAFQ93_RS09130 (AAFQ93_09065) mecA 1915298..1916035 (-) 738 WP_375555245.1 adaptor protein MecA Regulator
  AAFQ93_RS09135 (AAFQ93_09070) - 1916162..1917640 (+) 1479 WP_049526250.1 oligosaccharide flippase family protein -
  AAFQ93_RS09140 (AAFQ93_09075) - 1917819..1919078 (-) 1260 WP_375555246.1 TRZ/ATZ family protein -
  AAFQ93_RS09145 (AAFQ93_09080) - 1919119..1919244 (-) 126 WP_265340260.1 hypothetical protein -

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28432.23 Da        Isoelectric Point: 3.9576

>NTDB_id=989191 AAFQ93_RS09130 WP_375555245.1 1915298..1916035(-) (mecA) [Streptococcus nidrosiense strain SO-23-1]
MKMKQISDTTLKITMSLEDLMDRGMEIADFLVPQEKTEEFFYAILDELEMPDSFLDTGMLSFRVTPKPDKVDVFVTKSKI
DQNLDFDDLADLPDMDELAKMSPDEFLKTLEKTMAEKTKDDIEAIQSLEQVEKEEEAALDEALEVEEGKREPYIYYILRF
DDLSSLVSFAKTVDYQMETSELYKMKDQYYLTVLVDVEDQPSLYPAWLLARMREFADDSDISRSVLQEYGQLLINHDAVQ
GLQKV

Nucleotide


Download         Length: 738 bp        

>NTDB_id=989191 AAFQ93_RS09130 WP_375555245.1 1915298..1916035(-) (mecA) [Streptococcus nidrosiense strain SO-23-1]
ATGAAAATGAAACAAATCAGTGATACGACTTTAAAAATCACCATGTCTTTGGAAGATTTGATGGATCGTGGAATGGAAAT
CGCAGACTTTCTCGTTCCACAAGAGAAAACAGAAGAATTTTTCTACGCAATCTTGGATGAGCTAGAGATGCCAGATAGCT
TCTTGGATACGGGTATGCTCAGCTTCCGAGTAACACCTAAGCCAGACAAGGTTGATGTTTTTGTGACAAAATCTAAGATC
GACCAGAATTTAGATTTTGACGATTTGGCAGATCTTCCTGATATGGATGAGTTGGCTAAAATGTCTCCAGATGAGTTTTT
AAAAACCTTGGAGAAAACTATGGCAGAAAAAACTAAAGATGATATTGAAGCCATTCAATCTTTAGAGCAGGTTGAAAAGG
AAGAAGAAGCAGCGCTTGACGAAGCCCTCGAAGTAGAAGAAGGAAAAAGAGAGCCTTATATCTACTATATCTTACGTTTT
GACGATTTATCTAGTTTGGTTTCTTTTGCCAAAACGGTTGACTACCAAATGGAAACTTCAGAACTCTACAAGATGAAAGA
CCAGTACTATCTGACAGTCTTAGTTGATGTAGAAGATCAACCTAGCCTTTATCCAGCTTGGTTGTTGGCACGTATGCGAG
AATTTGCGGATGATAGTGATATCAGTCGTTCTGTCCTACAAGAATATGGGCAACTACTCATCAATCATGATGCTGTCCAA
GGACTCCAAAAAGTTTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus pneumoniae Rx1

81.633

100

0.816
  mecA Streptococcus pneumoniae D39

81.633

100

0.816
  mecA Streptococcus pneumoniae R6

81.633

100

0.816
  mecA Streptococcus pneumoniae TIGR4

81.633

100

0.816
  mecA Streptococcus mutans UA159

52.033

100

0.522
  mecA Streptococcus thermophilus LMD-9

48.193

100

0.49
  mecA Streptococcus thermophilus LMG 18311

47.791

100

0.486

Multiple sequence alignment