Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   R8568_RS00240 Genome accession   NZ_AP026931
Coordinates   44063..45412 (+) Length   449 a.a.
NCBI ID   WP_000801631.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701541     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 39063..50412
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8568_RS00210 (PC1520_00350) plsX 39183..40175 (+) 993 WP_000717458.1 phosphate acyltransferase PlsX -
  R8568_RS00215 (PC1520_00360) - 40181..40414 (+) 234 WP_000136447.1 acyl carrier protein -
  R8568_RS00220 (PC1520_00370) - 40451..40750 (+) 300 Protein_36 transposase family protein -
  R8568_RS00225 (PC1520_00380) blpU 40953..41183 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  R8568_RS00230 - 41186..41311 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  R8568_RS00235 (PC1520_00390) comA 41897..44050 (+) 2154 WP_000668304.1 peptide cleavage/export ABC transporter ComA Regulator
  R8568_RS00240 (PC1520_00400) comB 44063..45412 (+) 1350 WP_000801631.1 competence pheromone export protein ComB Regulator
  R8568_RS00245 (PC1520_00410) purC 45582..46289 (+) 708 WP_000043304.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  R8568_RS00250 - 46291..46434 (+) 144 WP_050167432.1 hypothetical protein -
  R8568_RS00255 (PC1520_00420) - 46491..50216 (+) 3726 WP_000361187.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49645.51 Da        Isoelectric Point: 5.3895

>NTDB_id=98797 R8568_RS00240 WP_000801631.1 44063..45412(+) (comB) [Streptococcus pneumoniae strain PZ900701541]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGTEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGASLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=98797 R8568_RS00240 WP_000801631.1 44063..45412(+) (comB) [Streptococcus pneumoniae strain PZ900701541]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGACAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTCCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCAACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.886

100

0.989
  comB Streptococcus pneumoniae Rx1

98.664

100

0.987
  comB Streptococcus pneumoniae D39

98.664

100

0.987
  comB Streptococcus pneumoniae R6

98.664

100

0.987
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555

Multiple sequence alignment