Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   R8624_RS00230 Genome accession   NZ_AP026930
Coordinates   42664..44013 (+) Length   449 a.a.
NCBI ID   WP_050233557.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900701208     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 37664..49013
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8624_RS00200 (PC1195_00330) plsX 37782..38774 (+) 993 WP_050311686.1 phosphate acyltransferase PlsX -
  R8624_RS00205 (PC1195_00340) - 38780..39013 (+) 234 WP_000659556.1 acyl carrier protein -
  R8624_RS00210 - 39050..39350 (+) 301 Protein_34 transposase family protein -
  R8624_RS00215 blpU 39553..39783 (+) 231 Protein_35 bacteriocin-like peptide BlpU -
  R8624_RS00220 (PC1195_00350) - 39786..39911 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  R8624_RS00225 (PC1195_00360) comA 40498..42651 (+) 2154 WP_000668304.1 peptide cleavage/export ABC transporter ComA Regulator
  R8624_RS00230 (PC1195_00370) comB 42664..44013 (+) 1350 WP_050233557.1 competence pheromone export protein ComB Regulator
  R8624_RS00235 (PC1195_00380) purC 44183..44890 (+) 708 WP_000043306.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  R8624_RS00240 - 44892..45035 (+) 144 WP_050167432.1 hypothetical protein -
  R8624_RS00245 (PC1195_00390) - 45092..48817 (+) 3726 WP_317650167.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49675.59 Da        Isoelectric Point: 5.3895

>NTDB_id=98719 R8624_RS00230 WP_050233557.1 42664..44013(+) (comB) [Streptococcus pneumoniae strain PZ900701208]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAMETGAFLASQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=98719 R8624_RS00230 WP_050233557.1 42664..44013(+) (comB) [Streptococcus pneumoniae strain PZ900701208]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATGGAAACAGGTGCTTTCTTGGCCAGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACATTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCCTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCAACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

98.886

100

0.989
  comB Streptococcus pneumoniae D39

98.664

100

0.987
  comB Streptococcus pneumoniae R6

98.664

100

0.987
  comB Streptococcus pneumoniae Rx1

98.664

100

0.987
  comB Streptococcus mitis SK321

94.878

100

0.949
  comB Streptococcus mitis NCTC 12261

94.432

100

0.944
  comB Streptococcus gordonii str. Challis substr. CH1

55.333

100

0.555

Multiple sequence alignment