Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   NST80_RS02390 Genome accession   NZ_CP152039
Coordinates   457655..458398 (-) Length   247 a.a.
NCBI ID   WP_014634051.1    Uniprot ID   -
Organism   Streptococcus sp. FSL K6-1323     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 452655..463398
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS02370 (NST80_02370) - 453285..453977 (+) 693 WP_002886745.1 hypothetical protein -
  NST80_RS02375 (NST80_02375) - 454296..454955 (+) 660 WP_118172469.1 ABC transporter ATP-binding protein -
  NST80_RS02380 (NST80_02380) - 454970..455686 (+) 717 WP_049529172.1 hypothetical protein -
  NST80_RS02385 (NST80_02385) - 456338..457645 (-) 1308 WP_342504625.1 GHKL domain-containing protein -
  NST80_RS02390 (NST80_02390) comE/blpR 457655..458398 (-) 744 WP_014634051.1 response regulator transcription factor Regulator
  NST80_RS02395 (NST80_02395) - 458898..459251 (+) 354 WP_013990160.1 hypothetical protein -
  NST80_RS02400 (NST80_02400) tnpA 459828..460244 (+) 417 WP_002886752.1 IS200/IS605 family transposase -
  NST80_RS02405 (NST80_02405) - 460562..461485 (+) 924 WP_183138109.1 XRE family transcriptional regulator -
  NST80_RS02410 (NST80_02410) - 461624..462316 (+) 693 WP_013990164.1 DUF6287 domain-containing protein -
  NST80_RS02415 (NST80_02415) - 462381..462671 (+) 291 WP_002885564.1 hypothetical protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28712.13 Da        Isoelectric Point: 6.2535

>NTDB_id=986308 NST80_RS02390 WP_014634051.1 457655..458398(-) (comE/blpR) [Streptococcus sp. FSL K6-1323]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMNKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLFRCHRSFIVNPENIVRINKEDKMVMFENNNECPISRTKYKALLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=986308 NST80_RS02390 WP_014634051.1 457655..458398(-) (comE/blpR) [Streptococcus sp. FSL K6-1323]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCGAAAGAAATCCGAAAAAAA
GACCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATTGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGAATAAAA
TGGGTGCTACTATCGCTCAAGATTCATTTACTTTTGAAACAGCTACGGCTCAAGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACGTCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGCATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGATGACCGCCTATTTCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAGGATCA
ATAAAGAAGATAAAATGGTCATGTTTGAAAATAATAATGAATGTCCCATTTCGCGTACGAAATATAAGGCCCTCCTAGAA
AAAGTTAAATCTTTGAAAAGCTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-123)

LytTr DNA-binding domain (LytTR)

(152-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

54.812

96.761

0.53
  comE/comE1 Streptococcus equinus JB1

45.679

98.381

0.449
  comE/comE2 Streptococcus equinus JB1

39.837

99.595

0.397
  comE/comE2 Streptococcus gordonii strain NCTC7865

38.057

100

0.381
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

38.057

100

0.381

Multiple sequence alignment