Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NST80_RS01000 Genome accession   NZ_CP152039
Coordinates   177176..177925 (+) Length   249 a.a.
NCBI ID   WP_002886435.1    Uniprot ID   -
Organism   Streptococcus sp. FSL K6-1323     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 172176..182925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NST80_RS00980 (NST80_00980) - 173191..173931 (-) 741 WP_002886432.1 amino acid ABC transporter ATP-binding protein -
  NST80_RS00985 (NST80_00985) - 173931..175478 (-) 1548 WP_013989972.1 ABC transporter substrate-binding protein/permease -
  NST80_RS00990 (NST80_00990) - 175684..176538 (+) 855 WP_002883622.1 undecaprenyl-diphosphate phosphatase -
  NST80_RS00995 (NST80_00995) - 176598..176969 (-) 372 WP_118057865.1 DUF3021 family protein -
  NST80_RS01000 (NST80_01000) mecA 177176..177925 (+) 750 WP_002886435.1 adaptor protein MecA Regulator
  NST80_RS01005 (NST80_01005) - 177929..179086 (+) 1158 WP_118172028.1 MraY family glycosyltransferase -
  NST80_RS01010 (NST80_01010) sufC 179248..180018 (+) 771 WP_002883600.1 Fe-S cluster assembly ATPase SufC -
  NST80_RS01015 (NST80_01015) sufD 180055..181317 (+) 1263 WP_049529344.1 Fe-S cluster assembly protein SufD -
  NST80_RS01020 (NST80_01020) - 181371..182603 (+) 1233 WP_118172029.1 cysteine desulfurase -

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29072.63 Da        Isoelectric Point: 4.0148

>NTDB_id=986292 NST80_RS01000 WP_002886435.1 177176..177925(+) (mecA) [Streptococcus sp. FSL K6-1323]
MEMKQISETTLKIMITMEDLEEHGMELKDFLIPQEKTEEFFYTVMDELDLPDNFKNSGMLSFRVTPRKDRVDVFVTKSDL
KEDLDFNDLSDMDDYSGLSPEEFLKALEGNFMDKGDIEAHHKLEELEKTLEEVDKAMTEPTKEVAEENIREDYTHYVLAF
SDFDQVVTFTQGLKDVPVEGSELYKLGDVYYMTILLYLADEPDYYANNMYARFLEYANVADRTRAYLQEHATILMEDDAL
PVLQATKWS

Nucleotide


Download         Length: 750 bp        

>NTDB_id=986292 NST80_RS01000 WP_002886435.1 177176..177925(+) (mecA) [Streptococcus sp. FSL K6-1323]
ATGGAAATGAAACAAATAAGCGAGACAACTCTAAAAATCATGATTACCATGGAAGATCTTGAAGAACATGGTATGGAATT
GAAGGATTTCTTGATTCCCCAGGAAAAAACAGAGGAATTTTTCTATACTGTCATGGATGAGTTGGACTTGCCTGATAACT
TTAAAAATAGTGGGATGCTGAGCTTCCGTGTCACGCCACGCAAGGATCGTGTGGATGTCTTTGTGACTAAATCAGATCTT
AAGGAAGACCTTGATTTCAACGATTTGTCAGATATGGATGACTATTCAGGGCTTTCTCCAGAAGAGTTTCTAAAGGCCCT
TGAGGGTAACTTTATGGACAAGGGTGACATCGAAGCACACCATAAGCTCGAAGAGCTTGAAAAGACCTTGGAAGAGGTTG
ATAAGGCTATGACAGAGCCTACCAAGGAAGTGGCTGAAGAAAATATTCGTGAAGACTATACCCACTATGTCTTGGCCTTC
TCTGATTTTGATCAAGTGGTGACTTTTACGCAAGGTTTGAAGGATGTACCTGTTGAAGGTTCTGAGCTTTATAAACTTGG
GGATGTCTACTACATGACGATCCTTCTTTACTTGGCTGATGAGCCTGATTATTACGCGAACAATATGTATGCGCGTTTTC
TTGAATATGCGAATGTGGCAGACCGAACACGTGCCTACCTACAAGAGCATGCAACAATCTTGATGGAAGATGATGCTTTA
CCGGTACTACAAGCAACGAAATGGAGCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-242)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Streptococcus thermophilus LMD-9

93.976

100

0.94
  mecA Streptococcus thermophilus LMG 18311

93.173

100

0.932
  mecA Streptococcus mutans UA159

60.246

97.992

0.59
  mecA Streptococcus pneumoniae Rx1

47.39

100

0.474
  mecA Streptococcus pneumoniae D39

47.39

100

0.474
  mecA Streptococcus pneumoniae R6

47.39

100

0.474
  mecA Streptococcus pneumoniae TIGR4

47.39

100

0.474

Multiple sequence alignment