Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   NYE28_RS05855 Genome accession   NZ_CP152013
Coordinates   1137930..1138586 (+) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus sp. FSL R5-0443     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 1132930..1143586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NYE28_RS05830 (NYE28_05830) oppF 1133459..1134376 (+) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -
  NYE28_RS05835 (NYE28_05835) - 1134483..1135670 (+) 1188 WP_015239569.1 putative glycoside hydrolase -
  NYE28_RS05840 (NYE28_05840) - 1135788..1136366 (+) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  NYE28_RS05845 (NYE28_05845) spx 1136545..1136940 (+) 396 WP_003155034.1 transcriptional regulator Spx -
  NYE28_RS05850 (NYE28_05850) - 1136998..1137654 (-) 657 WP_007409109.1 TerC family protein -
  NYE28_RS05855 (NYE28_05855) mecA 1137930..1138586 (+) 657 WP_003155032.1 adaptor protein MecA Regulator
  NYE28_RS05860 (NYE28_05860) - 1138737..1139897 (+) 1161 WP_132106271.1 competence protein CoiA family protein -
  NYE28_RS05865 (NYE28_05865) pepF 1140125..1141954 (+) 1830 WP_094031915.1 oligoendopeptidase F Regulator
  NYE28_RS05870 (NYE28_05870) - 1141992..1142159 (-) 168 WP_003155026.1 hypothetical protein -
  NYE28_RS05875 (NYE28_05875) spxH 1142445..1143347 (-) 903 WP_003155024.1 protease adaptor protein SpxH -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=984887 NYE28_RS05855 WP_003155032.1 1137930..1138586(+) (mecA) [Bacillus sp. FSL R5-0443]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=984887 NYE28_RS05855 WP_003155032.1 1137930..1138586(+) (mecA) [Bacillus sp. FSL R5-0443]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGACGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATTAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment