Detailed information NTG0098180

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: R8625_RS04395
• Genome accession: NZ_AP026923
• Coordinates: 863367..865607 (+)
• Length: 746 a.a.
• NCBI ID: WP_023396235.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700054
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 858367..870607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8625_RS04360 (PC0054_08620)	pyrH	858457..859194 (+)	738	WP_000002997.1	UMP kinase	-
R8625_RS04365 (PC0054_08630)	frr	859203..859760 (+)	558	WP_000024409.1	ribosome recycling factor	-
R8625_RS04370 (PC0054_08640)	cvfB	859820..860674 (+)	855	WP_317649393.1	RNA-binding virulence regulatory protein CvfB	-
R8625_RS04375 (PC0054_08650)	-	860683..860898 (+)	216	WP_001232085.1	YozE family protein	-
R8625_RS04380 (PC0054_08660)	-	860984..861988 (+)	1005	WP_000658185.1	PhoH family protein	-
R8625_RS04385 (PC0054_08670)	-	862096..862665 (+)	570	WP_000443751.1	GNAT family N-acetyltransferase	-
R8625_RS04390 (PC0054_08680)	comEA/celA/cilE	862733..863383 (+)	651	WP_000387336.1	ComEA family DNA-binding protein	Machinery gene
R8625_RS04395 (PC0054_08690)	comEC/celB	863367..865607 (+)	2241	WP_023396235.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
R8625_RS04400 (PC0054_08700)	-	865786..865974 (+)	189	WP_023396236.1	hypothetical protein	-
R8625_RS04405 (PC0054_08710)	-	866006..866593 (+)	588	WP_000933542.1	ATP-binding cassette domain-containing protein	-
R8625_RS04410 (PC0054_08720)	-	866597..867778 (+)	1182	WP_000655945.1	hypothetical protein	-
R8625_RS04415 (PC0054_08730)	infC	868085..868615 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
R8625_RS04420 (PC0054_08740)	rpmI	868648..868848 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
R8625_RS04425 (PC0054_08750)	rplT	868900..869259 (+)	360	WP_000124836.1	50S ribosomal protein L20	-
R8625_RS04430 (PC0054_08760)	-	869317..869697 (+)	381	WP_000157154.1	VOC family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84516.96 Da
• Isoelectric Point: 9.5181

>NTDB_id=98180 R8625_RS04395 WP_023396235.1 863367..865607(+) (comEC/celB) [Streptococcus pneumoniae strain PZ900700054]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSASYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFVFQNWQQSQASQN
LADSVERVRILPDTIKVNGDSLSFRGKSNGRAFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPEGQRNFGGFNYQAY
LKTQGIYQTLNIKTIQSLQKIGSWDIGENLSSLRRKAVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNELYSSLGIIHL
FALSGMQVGFFMNGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVTSESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLTFLPLLSI
LFVLSFLYPVIQLNFIFEWLEGIIRLVSQVTSRPLVFGQPNAWFLILLLISLALVYDLRKNIKKLTVLCLLITGLFLLTK
HPLENEITMLDVGQGESIFLRDVTGKTILIDVGGKAESYKKIEKWQEKMTTSNAQRTLIPYLKSRGVAKIDQLILTNTDK
ENVGDLSEVTKAFHVGEILVSKDSLKQKEFVAELQTTQTKVRSMTVGENLPIFGSQLEVLSPRKMGDGGHDDTLVLYGKF
LDKQFLFTGNLEEKGEKDLLKHYPDLKVNVLKASQHGNKKSSSPAFLEKLKPELTLISVGKSNRMKLPHQETLTRLEGIN
SKVYRTDQQGAIRFKGVDSWKIESVR

Nucleotide

• Length: 2241 bp

>NTDB_id=98180 R8625_RS04395 WP_023396235.1 863367..865607(+) (comEC/celB) [Streptococcus pneumoniae strain PZ900700054]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTGAGTTTTCTATTACTTTGGCTTTATTACGCTATTTT
CTCAGCATCTTATCTTGCTTTGTTGGGCTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGCGGAATCTTTGGATTTTGGTTTGTTTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
CTGGCGGATTCTGTTGAAAGGGTACGGATTTTGCCTGATACTATTAAGGTTAATGGTGATAGTCTATCCTTTCGTGGCAA
GTCTAACGGTCGTGCTTTCCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TGCATGAGATAGGACTAGAAGGGAAGCTTTCGGAGCCAGAAGGGCAGAGAAATTTTGGTGGCTTTAATTACCAAGCCTAT
CTGAAGACTCAGGGAATTTACCAGACTCTCAATATCAAAACAATCCAGTCACTTCAAAAGATTGGCAGTTGGGATATAGG
AGAAAACTTGTCCAGTTTACGTCGAAAGGCTGTGGTTTGGATTAAGACGCACTTTCCAGACCCTATGCGCAATTACATGA
CAGGACTCTTGCTGGGACATCTGGACACCGACTTTGAGGAGATGAATGAGCTTTATTCCAGTCTAGGAATTATCCACCTC
TTTGCCCTATCTGGTATGCAGGTAGGTTTTTTCATGAATGGATTTAAGAAACTTCTCTTGCGATTGGGCTTGACCCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCGGGACTAACTGGATTTTCAGCATCGGTTATTCGCAGTC
TCTTGCAAAAGCTACTGGCTCAACATGGGGTTAAGGGCTTGGATAATTTTGCCTTGACGGTGCTTGTCCTCTTTATTGTC
ATGCCAAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCCTGACCATGACCAGCAAAGAAGG
GGAGGGGCTCAAGGCTGTTACTAGTGAAAGTCTAGTCATCTCCTTGGGCATATTGCCCATTCTATCCTTCTATTTTGCGG
AATTTCAACCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTATTTGACTTGACCTTCTTACCGCTCTTGTCTATT
TTATTTGTCCTTTCCTTTCTCTATCCAGTCATTCAGCTGAACTTTATCTTTGAATGGTTGGAGGGCATTATTCGCTTGGT
GTCACAGGTGACAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGTTTTTAATCCTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGAAAAAACATTAAAAAGCTAACGGTATTGTGCTTATTGATTACAGGGCTCTTTCTCCTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTGGGGCAAGGAGAAAGTATTTTCCTACGGGATGTAACTGGGAAAAC
CATTCTCATAGATGTAGGTGGTAAGGCAGAATCTTATAAGAAAATCGAAAAATGGCAAGAAAAGATGACGACCAGCAATG
CCCAGCGAACCTTGATTCCCTATCTCAAAAGTCGAGGAGTAGCTAAGATTGACCAGCTAATTTTGACTAACACGGACAAG
GAGAATGTTGGAGATTTGTCAGAGGTGACCAAGGCTTTCCATGTAGGGGAGATTCTAGTATCAAAAGACAGTCTGAAACA
GAAGGAATTTGTGGCAGAACTACAGACGACTCAAACAAAGGTGCGTAGTATGACAGTAGGGGAGAACTTGCCCATTTTTG
GAAGTCAGTTAGAAGTTCTATCTCCAAGGAAAATGGGAGATGGAGGACACGATGACACCCTAGTTCTGTATGGGAAATTC
TTGGATAAGCAATTTCTCTTCACGGGAAATTTGGAGGAGAAAGGAGAGAAGGACTTGCTGAAGCACTATCCAGACTTGAA
AGTAAATGTTTTGAAAGCCAGCCAACATGGCAATAAAAAATCATCAAGTCCAGCCTTTCTAGAAAAACTCAAACCAGAGC
TTACTCTTATCTCAGTTGGAAAGAGCAATCGAATGAAACTCCCCCATCAGGAAACATTGACACGACTGGAAGGTATCAAT
AGCAAAGTTTATCGAACTGACCAGCAAGGAGCTATACGTTTTAAGGGGGTGGATAGTTGGAAAATCGAAAGTGTTCGATA
G

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (30-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus pneumoniae TIGR4	97.989	100	0.98
comEC/celB	Streptococcus pneumoniae D39	97.721	100	0.977
comEC/celB	Streptococcus pneumoniae R6	97.721	100	0.977
comEC/celB	Streptococcus pneumoniae Rx1	97.721	100	0.977
comEC/celB	Streptococcus mitis NCTC 12261	91.946	99.866	0.918
comEC/celB	Streptococcus mitis SK321	91.689	100	0.917
comEC	Lactococcus lactis subsp. cremoris KW2	44.265	99.33	0.44