Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   R8625_RS00230 Genome accession   NZ_AP026923
Coordinates   41813..43162 (+) Length   449 a.a.
NCBI ID   WP_050214715.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700054     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 36813..48162
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8625_RS00200 (PC0054_00330) plsX 37005..37997 (+) 993 WP_000717456.1 phosphate acyltransferase PlsX -
  R8625_RS00205 (PC0054_00340) - 38003..38236 (+) 234 WP_000136447.1 acyl carrier protein -
  R8625_RS00210 (PC0054_00350) - 38273..38572 (+) 300 Protein_34 transposase family protein -
  R8625_RS00215 (PC0054_00360) - 38775..38933 (+) 159 WP_050214718.1 bacteriocin class II family protein -
  R8625_RS00220 - 38936..39061 (+) 126 WP_001842754.1 PncF family bacteriocin immunity protein -
  R8625_RS00225 (PC0054_00370) comA 39647..41800 (+) 2154 WP_050214717.1 peptide cleavage/export ABC transporter ComA Regulator
  R8625_RS00230 (PC0054_00380) comB 41813..43162 (+) 1350 WP_050214715.1 competence pheromone export protein ComB Regulator
  R8625_RS00235 (PC0054_00390) purC 43332..44039 (+) 708 WP_000043300.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  R8625_RS00240 - 44041..44160 (+) 120 WP_078143810.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  R8625_RS00245 (PC0054_00400) - 44241..47966 (+) 3726 WP_050228403.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49713.53 Da        Isoelectric Point: 5.1441

>NTDB_id=98165 R8625_RS00230 WP_050214715.1 41813..43162(+) (comB) [Streptococcus pneumoniae strain PZ900700054]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGTSLADQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESDKKVQGNLLDKGKITASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKDVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=98165 R8625_RS00230 WP_050214715.1 41813..43162(+) (comB) [Streptococcus pneumoniae strain PZ900700054]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTCGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAAAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTACTTCCTTGGCCGATCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATCTTGG
AGGCAGAGTCAGATAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAATTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAAGATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTATCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae Rx1

99.109

100

0.991
  comB Streptococcus pneumoniae D39

99.109

100

0.991
  comB Streptococcus pneumoniae R6

99.109

100

0.991
  comB Streptococcus pneumoniae TIGR4

98.886

100

0.989
  comB Streptococcus mitis SK321

94.655

100

0.947
  comB Streptococcus mitis NCTC 12261

94.209

100

0.942
  comB Streptococcus gordonii str. Challis substr. CH1

55.556

100

0.557

Multiple sequence alignment