Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   ACLQ7P_RS22405 Genome accession   NZ_CP181322
Coordinates   4213670..4214872 (-) Length   400 a.a.
NCBI ID   WP_121591341.1    Uniprot ID   -
Organism   Bacillus subtilis subsp. subtilis strain JCK-1398     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4208670..4219872
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACLQ7P_RS22380 (ACLQ7P_22380) rocE 4208904..4210307 (-) 1404 WP_017695780.1 amino acid permease -
  ACLQ7P_RS22385 (ACLQ7P_22385) rocD 4210530..4211735 (-) 1206 WP_041337907.1 ornithine aminotransferase -
  ACLQ7P_RS22390 (ACLQ7P_22390) rocR 4211973..4213358 (+) 1386 WP_416247260.1 arginine utilization regulatory protein RocR -
  ACLQ7P_RS22395 (ACLQ7P_22395) - 4213340..4213492 (-) 153 Protein_4361 ATP-binding protein -
  ACLQ7P_RS22400 (ACLQ7P_22400) - 4213520..4213650 (-) 131 Protein_4362 hypothetical protein -
  ACLQ7P_RS22405 (ACLQ7P_22405) htrA 4213670..4214872 (-) 1203 WP_121591341.1 serine protease HtrC Regulator
  ACLQ7P_RS22410 (ACLQ7P_22410) vicX 4214954..4215748 (-) 795 WP_003226939.1 MBL fold metallo-hydrolase Regulator
  ACLQ7P_RS22415 (ACLQ7P_22415) walI 4215770..4216612 (-) 843 WP_121591342.1 WalRK two-component regulatory system regulator WalI -
  ACLQ7P_RS22420 (ACLQ7P_22420) walH 4216599..4217966 (-) 1368 WP_041352271.1 WalRK two-component regulatory system regulator WalH -
  ACLQ7P_RS22425 (ACLQ7P_22425) walK 4217956..4219791 (-) 1836 WP_017695786.1 cell wall metabolism sensor histidine kinase WalK -

Sequence

Protein


Download         Length: 400 a.a.        Molecular weight: 42840.74 Da        Isoelectric Point: 5.5235

>NTDB_id=979304 ACLQ7P_RS22405 WP_121591341.1 4213670..4214872(-) (htrA) [Bacillus subtilis subsp. subtilis strain JCK-1398]
MVNYEREEEHTTPEQPKRSKKGYFLSSLIGVIVGAVLMAFIMPYLSNEGLDTGVLDQQQNNNGRESIRTVNVSVNNAVTK
IVSNVSPAVVGVVNIQKSDILGESGEAGSGSGVIYKKNDHSAYVVTNHHVIEGASQIEISLKDGSRVPADLVGSDQLMDL
AVLRVKSDKIKAVADFGNSDKVKSGEPVIAIGNPLGLEFAGSVTQGVISGTERAIPVDSNGDGQPDWNAEVLQTDAAINP
GNSGGALLNMDGKVIGINSMKIAESAVEGIGLSIPSKLVIPVIEDLERYGKVKRPFLGIEMKSLSDIASYHWYETLKLPK
NVTNGVVVMGVDAFSPAAKAGLKELDVITEFDGYKVNDIVDLRKRLYQKKVGDWVKVKFYRGGKEKSVDIKLSSADQLGS

Nucleotide


Download         Length: 1203 bp        

>NTDB_id=979304 ACLQ7P_RS22405 WP_121591341.1 4213670..4214872(-) (htrA) [Bacillus subtilis subsp. subtilis strain JCK-1398]
ATGGTGAATTATGAACGTGAGGAAGAACATACTACTCCTGAACAGCCAAAGAGAAGCAAAAAAGGATATTTTCTTTCGAG
TCTGATTGGCGTGATTGTCGGTGCCGTATTAATGGCGTTTATCATGCCGTACCTTTCAAATGAAGGGCTGGATACAGGCG
TCTTAGATCAGCAGCAAAACAACAACGGCCGGGAATCAATCAGGACGGTGAATGTCAGTGTCAACAATGCCGTCACCAAG
ATTGTCAGCAATGTGTCGCCCGCCGTTGTCGGTGTTGTGAACATCCAAAAATCAGATATTTTGGGAGAGAGCGGCGAGGC
TGGGAGCGGCTCAGGCGTCATCTATAAGAAAAATGACCATTCCGCTTATGTCGTGACCAACCATCATGTCATCGAAGGCG
CTTCCCAAATTGAAATCAGCTTGAAAGACGGATCGCGTGTACCAGCTGATCTTGTCGGCAGCGACCAGCTGATGGACCTT
GCTGTTTTACGGGTGAAAAGCGATAAAATTAAAGCAGTCGCCGATTTCGGAAATTCAGATAAAGTGAAGTCTGGGGAGCC
GGTTATTGCGATCGGGAACCCGTTAGGCCTTGAGTTTGCTGGCTCTGTCACACAAGGCGTCATCTCGGGTACGGAGAGGG
CGATCCCAGTAGATTCAAACGGTGATGGACAGCCTGACTGGAACGCAGAAGTCCTGCAAACAGATGCGGCCATTAACCCT
GGGAACAGCGGCGGCGCTTTGTTAAATATGGATGGGAAGGTCATTGGCATCAATTCAATGAAAATTGCCGAGTCAGCGGT
TGAAGGGATTGGCCTGTCCATTCCGTCTAAGCTCGTGATCCCTGTGATAGAGGATTTAGAGAGATACGGAAAGGTCAAAC
GCCCGTTCCTTGGCATTGAGATGAAATCCCTAAGCGACATCGCAAGCTATCATTGGTATGAAACATTAAAGCTTCCTAAG
AACGTCACCAATGGAGTGGTTGTGATGGGTGTAGACGCCTTTTCACCTGCCGCAAAAGCGGGGCTGAAGGAACTGGATGT
CATCACGGAATTTGACGGATACAAAGTAAATGATATTGTTGACCTGCGAAAACGGCTTTATCAGAAAAAAGTCGGTGACT
GGGTGAAGGTGAAGTTTTATCGCGGCGGAAAAGAAAAATCTGTTGATATCAAGCTGTCCTCCGCAGACCAATTAGGCAGT
TAA

Domains

Predicted by InterProScan.

Trypsin-like peptidase domain (Trypsin_2)

(110-257)

Peptidase family M50 (Peptidase_M50)

(218-395)

PDZ domain (PDZ_2)

(295-392)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus mutans UA159

43.434

99

0.43
  htrA Streptococcus mitis NCTC 12261

43.523

96.5

0.42
  htrA Streptococcus gordonii str. Challis substr. CH1

41.397

100

0.415
  htrA Streptococcus pneumoniae TIGR4

44.848

82.5

0.37
  htrA Streptococcus pneumoniae D39

44.848

82.5

0.37
  htrA Streptococcus pneumoniae Rx1

44.848

82.5

0.37
  htrA Streptococcus pneumoniae R6

44.848

82.5

0.37