Detailed information NTG0097885

Bioinformatically predicted

Overview

• Name: cclA/cilC
• Type: Machinery gene
• Locus tag: R8613_RS08830
• Genome accession: NZ_AP026919
• Coordinates: 1702265..1702924 (+)
• Length: 219 a.a.
• NCBI ID: WP_061749374.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700012
• Function: processing and translocation of ComGC; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1697265..1707924

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8613_RS08790 (PC0012_17210)	mgaSpn	1697421..1698902 (-)	1482	WP_001205276.1	virulence factor transcriptional regulator MgaSpn	-
R8613_RS08795 (PC0012_17220)	-	1699345..1699509 (+)	165	WP_001809002.1	GlsB/YeaQ/YmgE family stress response membrane protein	-
R8613_RS08800	amaP	1699593..1700159 (+)	567	WP_000030213.1	alkaline shock response membrane anchor protein AmaP	-
R8613_RS08805 (PC0012_17240)	-	1700171..1700341 (+)	171	WP_000455066.1	DUF2273 domain-containing protein	-
R8613_RS08810 (PC0012_17250)	-	1700380..1700988 (+)	609	WP_000064115.1	Asp23/Gls24 family envelope stress response protein	-
R8613_RS08815 (PC0012_17260)	-	1701019..1701222 (+)	204	WP_000109957.1	CsbD family protein	-
R8613_RS08820 (PC0012_17270)	-	1701332..1701571 (-)	240	WP_001005784.1	transposase	-
R8613_RS08825 (PC0012_17280)	-	1701749..1702195 (-)	447	WP_061749375.1	GNAT family N-acetyltransferase	-
R8613_RS08830 (PC0012_17290)	cclA/cilC	1702265..1702924 (+)	660	WP_061749374.1	A24 family peptidase	Machinery gene
R8613_RS08835 (PC0012_17300)	-	1702976..1704127 (-)	1152	WP_000481756.1	XRE family transcriptional regulator	-
R8613_RS08840 (PC0012_17310)	-	1704142..1704873 (-)	732	WP_061749373.1	hypothetical protein	-
R8613_RS08845	-	1705093..1705203 (+)	111	Protein_1758	prepilin peptidase	-
R8613_RS08850 (PC0012_17320)	trpA	1705175..1705951 (-)	777	WP_050214585.1	tryptophan synthase subunit alpha	-
R8613_RS08855 (PC0012_17330)	trpB	1705944..1707167 (-)	1224	WP_000331289.1	tryptophan synthase subunit beta	-
R8613_RS08860 (PC0012_17340)	-	1707145..1707744 (-)	600	WP_000169887.1	phosphoribosylanthranilate isomerase	-

Sequence

Protein

• Length: 219 a.a.
• Molecular weight: 24841.98 Da
• Isoelectric Point: 8.2363

>NTDB_id=97885 R8613_RS08830 WP_061749374.1 1702265..1702924(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700012]
MIDFYFFLVGSILASFLGLVIDRFPEQSIISSASHCDSCQTPLRPLDLIPILSQVFNRFRCRYCKVRYPVWYALFELSLG
LLFLLYSWGWLSLGQVVLITAGLTLGIYDFHHQKYPLLVWMTFQLILIASSGWNLVMVSFLILGILAHFIDIRMGAGDFL
FLASCALVFSVTELLILIQFASATGILAFLLQKKKERLPFVPFLLLATCLIIFGKLLLV

Nucleotide

• Length: 660 bp

>NTDB_id=97885 R8613_RS08830 WP_061749374.1 1702265..1702924(+) (cclA/cilC) [Streptococcus pneumoniae strain PZ900700012]
ATGATTGATTTTTATTTTTTTCTCGTCGGGAGCATTCTCGCTTCCTTTCTTGGTTTGGTCATTGACCGTTTTCCAGAGCA
ATCCATTATCAGTTCAGCCAGTCACTGCGATTCCTGTCAGACTCCCTTGCGTCCTTTAGATTTGATTCCGATTCTCTCAC
AGGTCTTCAATCGCTTTCGCTGTCGCTACTGCAAAGTTCGCTATCCTGTCTGGTATGCCCTCTTTGAATTAAGCTTAGGA
CTCCTCTTTCTGCTTTACTCTTGGGGATGGCTCTCCTTGGGGCAAGTCGTCCTAATCACCGCTGGTTTGACCTTGGGTAT
CTACGACTTTCACCATCAGAAATATCCCTTACTGGTCTGGATGACTTTCCAGCTAATCCTAATAGCTTCCTCTGGCTGGA
ATCTGGTCATGGTCTCCTTCCTCATACTTGGAATTTTGGCTCATTTTATCGATATCCGCATGGGTGCAGGGGATTTCCTC
TTTTTAGCTTCTTGTGCTCTCGTCTTTAGCGTAACGGAGTTACTGATCTTGATTCAGTTCGCTTCTGCGACGGGTATCCT
GGCCTTTCTCCTGCAAAAGAAAAAGGAAAGACTTCCTTTCGTGCCTTTCCTCTTACTTGCTACTTGTTTGATTATTTTTG
GTAAGCTACTGCTTGTCTGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (8-88)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
cclA/cilC	Streptococcus pneumoniae TIGR4	99.543	100	0.995
cclA/cilC	Streptococcus pneumoniae Rx1	94.521	100	0.945
cclA/cilC	Streptococcus pneumoniae D39	94.521	100	0.945
cclA/cilC	Streptococcus pneumoniae R6	94.521	100	0.945
cclA/cilC	Streptococcus mitis SK321	91.324	100	0.913
cclA/cilC	Streptococcus mitis NCTC 12261	86.758	100	0.868