Detailed information NTG0097888

Bioinformatically predicted

Overview

• Name: comGE
• Type: Machinery gene
• Locus tag: ACGHT2_RS00760
• Genome accession: NZ_AP031455
• Coordinates: 112338..112631 (+)
• Length: 97 a.a.
• NCBI ID: WP_081048608.1
• Uniprot ID: -
• Organism: Streptococcus pasteurianus strain k46-0107-A9
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 107338..117631

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACGHT2_RS00735 (K460107A9_00930)	-	109335..109697 (+)	363	WP_058692629.1	DUF1033 family protein	-
ACGHT2_RS00740 (K460107A9_00940)	comGA	109768..110709 (+)	942	WP_003062917.1	competence type IV pilus ATPase ComGA	Machinery gene
ACGHT2_RS00745 (K460107A9_00950)	comGB	110633..111676 (+)	1044	WP_003062919.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACGHT2_RS00750 (K460107A9_00960)	comGC	111676..111969 (+)	294	WP_003062921.1	competence type IV pilus major pilin ComGC	Machinery gene
ACGHT2_RS00755 (K460107A9_00970)	comGD	111953..112384 (+)	432	WP_058692630.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACGHT2_RS00760 (K460107A9_00980)	comGE	112338..112631 (+)	294	WP_081048608.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACGHT2_RS00765 (K460107A9_00990)	comGF	112585..113052 (+)	468	WP_058692632.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACGHT2_RS00770 (K460107A9_01000)	comGG	113006..113356 (+)	351	WP_238374707.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACGHT2_RS00775 (K460107A9_01010)	comGH	113411..114382 (+)	972	WP_117479470.1	class I SAM-dependent methyltransferase	Machinery gene
ACGHT2_RS00780 (K460107A9_01020)	-	114420..115619 (+)	1200	WP_058692635.1	acetate kinase	-
ACGHT2_RS00785 (K460107A9_01030)	-	115786..115986 (+)	201	WP_058692636.1	helix-turn-helix transcriptional regulator	-
ACGHT2_RS00790 (K460107A9_01040)	-	115996..116202 (+)	207	WP_058692637.1	hypothetical protein	-
ACGHT2_RS00795 (K460107A9_01050)	-	116217..116645 (+)	429	WP_238374708.1	ABC transporter permease	-
ACGHT2_RS00800 (K460107A9_01060)	-	116657..117292 (+)	636	WP_058692639.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 97 a.a.
• Molecular weight: 11055.07 Da
• Isoelectric Point: 8.4757

>NTDB_id=97888 ACGHT2_RS00760 WP_081048608.1 112338..112631(+) (comGE) [Streptococcus pasteurianus strain k46-0107-A9]
MVNIKRQKLKAYILLESLIALGLLAMITSIVLGEIDKNRQFMQESLRQQEVLNVATMAVQTGQNHLKMNGIEVEIIKKDG
EVYVYEGKTEILHVKKD

Nucleotide

• Length: 294 bp

>NTDB_id=97888 ACGHT2_RS00760 WP_081048608.1 112338..112631(+) (comGE) [Streptococcus pasteurianus strain k46-0107-A9]
GTGGTAAATATAAAAAGACAGAAACTAAAAGCTTACATACTCCTTGAGAGCTTGATAGCACTAGGATTGTTAGCGATGAT
TACGAGTATTGTTTTAGGGGAAATTGATAAAAATAGGCAGTTTATGCAAGAAAGTTTACGGCAGCAGGAAGTTCTTAATG
TGGCAACAATGGCTGTGCAAACAGGGCAAAATCATTTGAAGATGAATGGTATTGAGGTTGAGATTATCAAAAAAGATGGA
GAGGTCTATGTTTATGAGGGGAAAACGGAAATATTACACGTTAAAAAAGACTAG

Domains

Predicted by InterProScan.

• Type II secretory pathway pseudopilin (ComGE) (13-94)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE	Streptococcus mutans UA140	46.875	98.969	0.464
comGE	Streptococcus mutans UA159	46.875	98.969	0.464
comGE/cglE	Streptococcus mitis SK321	41.489	96.907	0.402
comGE/cglE	Streptococcus pneumoniae Rx1	41.489	96.907	0.402
comGE/cglE	Streptococcus pneumoniae D39	41.489	96.907	0.402
comGE/cglE	Streptococcus pneumoniae R6	41.489	96.907	0.402
comGE/cglE	Streptococcus pneumoniae TIGR4	41.489	96.907	0.402
comGE/cglE	Streptococcus mitis NCTC 12261	40.426	96.907	0.392