Detailed information NTG0097850

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ACAM21_RS09695
• Genome accession: NZ_AP031395
• Coordinates: 1859022..1859921 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904865.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 16P29
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1854022..1864921

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACAM21_RS09670 (SPNE16P29_18920)	rsmA	1854358..1855230 (-)	873	WP_219599541.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
ACAM21_RS09675 (SPNE16P29_18930)	-	1855361..1855669 (-)	309	WP_000333257.1	hypothetical protein	-
ACAM21_RS09680 (SPNE16P29_18940)	-	1855662..1856303 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
ACAM21_RS09685 (SPNE16P29_18950)	-	1856305..1858335 (-)	2031	WP_369608092.1	bacteriocin-associated integral membrane family protein	-
ACAM21_RS09690 (SPNE16P29_18960)	-	1858412..1858708 (-)	297	WP_000815393.1	lactococcin 972 family bacteriocin	-
ACAM21_RS09695 (SPNE16P29_18970)	comR	1859022..1859921 (-)	900	WP_000904865.1	helix-turn-helix domain-containing protein	Regulator
ACAM21_RS09700 (SPNE16P29_18980)	rnmV	1859993..1860553 (-)	561	WP_000664448.1	ribonuclease M5	-
ACAM21_RS09705 (SPNE16P29_18990)	-	1860553..1861326 (-)	774	WP_000575635.1	TatD family hydrolase	-
ACAM21_RS09710 (SPNE16P29_19000)	-	1861631..1862608 (-)	978	Protein_1901	DUF1542 domain-containing protein	-
ACAM21_RS09715 (SPNE16P29_19010)	rpmH	1862814..1862948 (-)	135	WP_000831905.1	50S ribosomal protein L34	-
ACAM21_RS09720 (SPNE16P29_19020)	-	1863093..1864307 (-)	1215	WP_000666465.1	pyridoxal phosphate-dependent aminotransferase	-
ACAM21_RS09725 (SPNE16P29_19030)	-	1864463..1864756 (-)	294	WP_000977364.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35175.08 Da
• Isoelectric Point: 5.2018

>NTDB_id=97850 ACAM21_RS09695 WP_000904865.1 1859022..1859921(-) (comR) [Streptococcus pneumoniae strain 16P29]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTKLENFFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=97850 ACAM21_RS09695 WP_000904865.1 1859022..1859921(-) (comR) [Streptococcus pneumoniae strain 16P29]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAAAAGGTAACTAAATTAGAAAACTTCTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCGTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (70-291)

• Helix-turn-helix (HTH_3) (7-59)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	38.095	98.328	0.375
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368