Detailed information NTG0976797

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: MGAS38343_RS00700
• Genome accession: NZ_CP151438
• Coordinates: 105238..105672 (+)
• Length: 144 a.a.
• NCBI ID: WP_010921800.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS38343
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 100238..110672

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS38343_RS00670 (MGAS38343_00272)	-	101907..102272 (+)	366	WP_002986560.1	DUF1033 family protein	-
MGAS38343_RS00675 (MGAS38343_00274)	comYA	102365..103303 (+)	939	WP_010921798.1	competence type IV pilus ATPase ComGA	Machinery gene
MGAS38343_RS00680 (MGAS38343_00276)	comYB	103239..104273 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGAS38343_RS00685 (MGAS38343_00278)	comYC	104275..104601 (+)	327	WP_002986552.1	competence type IV pilus major pilin ComGC	Machinery gene
MGAS38343_RS00690 (MGAS38343_00280)	comGD	104576..105004 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
MGAS38343_RS00695 (MGAS38343_00282)	comGE	104961..105245 (+)	285	WP_002987779.1	competence type IV pilus minor pilin ComGE	-
MGAS38343_RS00700 (MGAS38343_00284)	comYF	105238..105672 (+)	435	WP_010921800.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGAS38343_RS00705 (MGAS38343_00286)	comGG	105656..105982 (+)	327	WP_010921801.1	competence type IV pilus minor pilin ComGG	-
MGAS38343_RS00710 (MGAS38343_00288)	comYH	106080..107033 (+)	954	WP_010921802.1	class I SAM-dependent methyltransferase	Machinery gene
MGAS38343_RS00715 (MGAS38343_00290)	-	107092..108288 (+)	1197	WP_010921803.1	acetate kinase	-
MGAS38343_RS00720	-	108475..108783 (+)	309	WP_010921804.1	hypothetical protein	-
MGAS38343_RS00725 (MGAS38343_00292)	proC	108866..109636 (-)	771	WP_010921805.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16654.28 Da
• Isoelectric Point: 10.2526

>NTDB_id=976797 MGAS38343_RS00700 WP_010921800.1 105238..105672(+) (comYF) [Streptococcus pyogenes strain MGAS38343]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTRTLLKHSHYLARHDQDNWLLFSHQLREELSGARFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIEQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=976797 MGAS38343_RS00700 WP_010921800.1 105238..105672(+) (comYF) [Streptococcus pyogenes strain MGAS38343]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCGAACCCTCCTTAAACATAGCCATTATCTAGCCCGTCATGATCAAGATAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGGTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTTCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGAGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	47.445	95.139	0.451
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae D39	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae R6	42.857	92.361	0.396
comGF/cglF	Streptococcus pneumoniae TIGR4	42.857	92.361	0.396
comGF/cglF	Streptococcus mitis SK321	42.105	92.361	0.389