Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   MGAS38343_RS00685 Genome accession   NZ_CP151438
Coordinates   104275..104601 (+) Length   108 a.a.
NCBI ID   WP_002986552.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS38343     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 99275..109601
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS38343_RS00670 (MGAS38343_00272) - 101907..102272 (+) 366 WP_002986560.1 DUF1033 family protein -
  MGAS38343_RS00675 (MGAS38343_00274) comYA 102365..103303 (+) 939 WP_010921798.1 competence type IV pilus ATPase ComGA Machinery gene
  MGAS38343_RS00680 (MGAS38343_00276) comYB 103239..104273 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  MGAS38343_RS00685 (MGAS38343_00278) comYC 104275..104601 (+) 327 WP_002986552.1 competence type IV pilus major pilin ComGC Machinery gene
  MGAS38343_RS00690 (MGAS38343_00280) comGD 104576..105004 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  MGAS38343_RS00695 (MGAS38343_00282) comGE 104961..105245 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  MGAS38343_RS00700 (MGAS38343_00284) comYF 105238..105672 (+) 435 WP_010921800.1 competence type IV pilus minor pilin ComGF Machinery gene
  MGAS38343_RS00705 (MGAS38343_00286) comGG 105656..105982 (+) 327 WP_010921801.1 competence type IV pilus minor pilin ComGG -
  MGAS38343_RS00710 (MGAS38343_00288) comYH 106080..107033 (+) 954 WP_010921802.1 class I SAM-dependent methyltransferase Machinery gene
  MGAS38343_RS00715 (MGAS38343_00290) - 107092..108288 (+) 1197 WP_010921803.1 acetate kinase -
  MGAS38343_RS00720 - 108475..108783 (+) 309 WP_010921804.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12376.36 Da        Isoelectric Point: 9.8992

>NTDB_id=976796 MGAS38343_RS00685 WP_002986552.1 104275..104601(+) (comYC) [Streptococcus pyogenes strain MGAS38343]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=976796 MGAS38343_RS00685 WP_002986552.1 104275..104601(+) (comYC) [Streptococcus pyogenes strain MGAS38343]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC Lactococcus lactis subsp. cremoris KW2

56.863

94.444

0.537
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC/cglC Streptococcus pneumoniae R6

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae D39

60.87

85.185

0.519
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae Rx1

60.87

85.185

0.519
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment