Detailed information NTG0976478

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: WMW89_RS10640
• Genome accession: NZ_CP151421
• Coordinates: 2224664..2225962 (+)
• Length: 432 a.a.
• NCBI ID: WP_033625178.1
• Uniprot ID: -
• Organism: Enterococcus faecalis strain HMRC07H23
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2219664..2230962

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
WMW89_RS10635 (WMW89_10630)	rlmH	2223784..2224263 (-)	480	WP_002355021.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
WMW89_RS10640 (WMW89_10635)	htrA	2224664..2225962 (+)	1299	WP_033625178.1	S1C family serine protease	Regulator
WMW89_RS10645 (WMW89_10640)	ytpR	2226009..2226629 (-)	621	WP_002361057.1	YtpR family tRNA-binding protein	-
WMW89_RS10650 (WMW89_10645)	-	2226840..2227295 (-)	456	WP_002385249.1	universal stress protein	-
WMW89_RS10655 (WMW89_10650)	-	2227443..2227757 (-)	315	WP_002355015.1	thioredoxin family protein	-
WMW89_RS10660 (WMW89_10655)	pepA	2227769..2228845 (-)	1077	WP_002355013.1	glutamyl aminopeptidase	-
WMW89_RS10665 (WMW89_10660)	-	2229152..2229493 (+)	342	WP_002355012.1	PepSY domain-containing protein	-

Sequence

Protein

• Length: 432 a.a.
• Molecular weight: 44861.98 Da
• Isoelectric Point: 4.9968

>NTDB_id=976478 WMW89_RS10640 WP_033625178.1 2224664..2225962(+) (htrA) [Enterococcus faecalis strain HMRC07H23]
MQRKDVTPNSDKKSLLQKFGIGLAGGLLGGALILGGAYSGIIPTPNGGNNAATTTSTNHGDTKVSNVSYNVSSDVTKAVK
KVQNSVVSVINMQSASNNSSADDPFGGLFGGNEGTQDSSSNNGNDLEAASEGSGVIYKKDGKTAYVVTNNHVVDKAQGLE
VVLSDGTKVKGELVGTDAYTDLAVIKISSDKVDQVAEFGNSSKITVGEPAIAIGSPLGSDYANSVTQGIISSVNRNITNK
NESGETININAIQTDAAINPGNSGGPLINIEGQVIGINSVKIVQSTSQVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPA
LGITMSDLTGISSQQQEQILKIPASVKTGVVVRGVEAATPAEKAGLEKYDVITKVDGQDVSSTTDLQSALYKKKVGDKME
VTYYRGSKEMKATIDLTIDKSALTQQNNRSNQ

Nucleotide

• Length: 1299 bp

>NTDB_id=976478 WMW89_RS10640 WP_033625178.1 2224664..2225962(+) (htrA) [Enterococcus faecalis strain HMRC07H23]
ATGCAACGAAAAGATGTTACACCTAATTCAGATAAAAAAAGTTTATTGCAAAAATTTGGGATTGGTTTAGCTGGCGGCTT
ACTTGGTGGCGCCCTTATTCTAGGAGGCGCTTATTCTGGGATTATTCCCACACCCAACGGCGGAAATAATGCGGCGACGA
CGACGTCCACTAATCACGGCGACACAAAAGTCAGCAATGTGAGTTACAATGTGTCTAGCGATGTCACAAAAGCCGTGAAA
AAAGTTCAAAATTCTGTGGTTTCTGTCATTAATATGCAAAGTGCTAGCAACAATTCTTCGGCAGATGATCCTTTTGGGGG
ATTGTTCGGTGGGAATGAAGGTACTCAAGACTCTTCCAGCAACAATGGTAACGATTTAGAAGCAGCCAGTGAAGGTAGTG
GGGTTATTTATAAGAAAGATGGTAAAACGGCTTATGTCGTGACAAATAACCACGTCGTAGATAAAGCGCAAGGATTGGAA
GTTGTTTTATCTGATGGTACCAAAGTGAAAGGCGAATTAGTCGGAACCGATGCTTACACGGATTTAGCCGTGATTAAAAT
TTCTTCCGACAAAGTTGATCAAGTCGCTGAGTTTGGGAATTCTAGTAAAATCACAGTCGGTGAGCCTGCTATTGCGATTG
GTTCCCCTCTAGGCTCTGATTATGCTAACTCTGTCACACAAGGAATCATCTCTTCTGTGAATAGAAATATTACCAATAAA
AACGAGTCTGGTGAAACCATCAATATTAATGCCATTCAAACCGATGCTGCCATCAATCCAGGAAACTCTGGTGGTCCACT
AATCAATATTGAAGGACAAGTCATTGGCATTAACTCAGTAAAAATTGTGCAATCAACTAGTCAAGTGAGCGTTGAAGGGA
TGGGCTTTGCCATTCCAAGTAATGACGTAGTCAACATTATCAACCAATTAGAAAAAGATGGTAAAGTGACGCGGCCAGCT
CTCGGGATTACGATGTCTGATTTAACAGGTATCTCTTCACAACAACAAGAACAAATTTTAAAAATTCCAGCTTCTGTAAA
AACTGGCGTAGTGGTTCGTGGTGTTGAAGCAGCGACCCCTGCTGAAAAGGCTGGATTGGAAAAATACGATGTTATCACGA
AAGTTGACGGCCAAGACGTAAGCTCTACTACAGATTTACAAAGCGCGCTTTACAAGAAAAAAGTTGGCGACAAAATGGAA
GTGACTTATTATCGTGGTTCTAAAGAAATGAAAGCAACTATCGATTTAACCATTGATAAATCAGCTTTAACACAACAAAA
TAATCGCAGCAATCAATAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (132-277)

• Peptidase family M50 (Peptidase_M50) (9-416)

• PDZ domain (PDZ_2) (319-416)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	53.659	94.907	0.509
htrA	Streptococcus mutans UA159	58.63	84.491	0.495
htrA	Streptococcus mitis NCTC 12261	55.135	85.648	0.472
htrA	Streptococcus pneumoniae TIGR4	55.807	81.713	0.456
htrA	Streptococcus pneumoniae Rx1	55.807	81.713	0.456
htrA	Streptococcus pneumoniae D39	55.807	81.713	0.456
htrA	Streptococcus pneumoniae R6	55.807	81.713	0.456