Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFC/cflB   Type   Machinery gene
Locus tag   R8775_RS10550 Genome accession   NZ_AP026915
Coordinates   2024294..2024956 (-) Length   220 a.a.
NCBI ID   WP_000649964.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain PZ900700005     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2019294..2029956
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R8775_RS10525 (PC0005_20350) - 2019444..2019710 (-) 267 WP_001278167.1 Veg family protein -
  R8775_RS10530 (PC0005_20360) dnaB 2019712..2021064 (-) 1353 WP_050114789.1 replicative DNA helicase -
  R8775_RS10535 (PC0005_20370) rplI 2021108..2021560 (-) 453 WP_050114792.1 50S ribosomal protein L9 -
  R8775_RS10540 (PC0005_20380) - 2021557..2023530 (-) 1974 WP_050205401.1 DHH family phosphoesterase -
  R8775_RS10545 (PC0005_20390) hpf 2023666..2024214 (-) 549 WP_000599107.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  R8775_RS10550 (PC0005_20400) comFC/cflB 2024294..2024956 (-) 663 WP_000649964.1 ComF family protein Machinery gene
  R8775_RS10555 (PC0005_20410) comFA/cflA 2024953..2026251 (-) 1299 WP_050233596.1 DEAD/DEAH box helicase Machinery gene
  R8775_RS10560 (PC0005_20420) - 2026307..2026942 (+) 636 WP_000395730.1 YigZ family protein -
  R8775_RS10565 (PC0005_20430) cysK 2027227..2028147 (+) 921 WP_000029866.1 cysteine synthase A -
  R8775_RS10570 - 2028386..2028760 (-) 375 Protein_2048 IS66 family transposase -
  R8775_RS10575 (PC0005_20450) - 2028733..2029041 (+) 309 Protein_2049 transposase -
  R8775_RS10580 (PC0005_20460) tnpB 2029196..2029519 (-) 324 WP_000586641.1 IS66 family insertion sequence element accessory protein TnpB -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 25253.15 Da        Isoelectric Point: 7.3688

>NTDB_id=97608 R8775_RS10550 WP_000649964.1 2024294..2024956(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700005]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSIKCQDCQLWCKEGVEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide


Download         Length: 663 bp        

>NTDB_id=97608 R8775_RS10550 WP_000649964.1 2024294..2024956(-) (comFC/cflB) [Streptococcus pneumoniae strain PZ900700005]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAATAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAGGGAGTTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

Phosphoribosyl transferase domain (Pribosyltran)

(153-219)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFC/cflB Streptococcus pneumoniae TIGR4

99.545

100

0.995
  comFC/cflB Streptococcus pneumoniae Rx1

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae D39

99.091

100

0.991
  comFC/cflB Streptococcus pneumoniae R6

99.091

100

0.991
  comFC/cflB Streptococcus mitis NCTC 12261

91.818

100

0.918
  comFC/cflB Streptococcus mitis SK321

90.909

100

0.909

Multiple sequence alignment