Detailed information NTG0976035

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: ACM3H0_RS06535
• Genome accession: NZ_CP180685
• Coordinates: 1216281..1216742 (-)
• Length: 153 a.a.
• NCBI ID: WP_001874060.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain M14
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1211281..1221742

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ACM3H0_RS06500 (ACM3H0_06500)	-	1211835..1212500 (-)	666	WP_000008111.1	CPBP family intramembrane glutamic endopeptidase	-
ACM3H0_RS06505 (ACM3H0_06505)	-	1212569..1213024 (-)	456	WP_000905674.1	hypothetical protein	-
ACM3H0_RS06510 (ACM3H0_06510)	-	1213065..1213202 (-)	138	WP_001867090.1	hypothetical protein	-
ACM3H0_RS06515 (ACM3H0_06515)	-	1213261..1213467 (-)	207	WP_000798242.1	helix-turn-helix transcriptional regulator	-
ACM3H0_RS06520 (ACM3H0_06520)	-	1213618..1214811 (-)	1194	WP_000047535.1	acetate kinase	-
ACM3H0_RS06525 (ACM3H0_06525)	comGH	1214843..1215817 (-)	975	WP_001008570.1	class I SAM-dependent methyltransferase	Machinery gene
ACM3H0_RS06530 (ACM3H0_06530)	comGG	1215932..1216303 (-)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
ACM3H0_RS06535 (ACM3H0_06535)	comGF	1216281..1216742 (-)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
ACM3H0_RS06540 (ACM3H0_06540)	comGE	1216696..1216995 (-)	300	WP_001867089.1	competence type IV pilus minor pilin ComGE	Machinery gene
ACM3H0_RS06545 (ACM3H0_06545)	comGD	1216967..1217395 (-)	429	WP_000793381.1	competence type IV pilus minor pilin ComGD	Machinery gene
ACM3H0_RS06550 (ACM3H0_06550)	comGB	1217392..1218435 (-)	1044	WP_223295592.1	competence type IV pilus assembly protein ComGB	Machinery gene
ACM3H0_RS06555 (ACM3H0_06555)	comGA	1218329..1219300 (-)	972	WP_000250808.1	competence type IV pilus ATPase ComGA	Machinery gene
ACM3H0_RS06560 (ACM3H0_06560)	-	1219473..1219838 (-)	366	WP_000285373.1	DUF1033 family protein	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17861.86 Da
• Isoelectric Point: 9.8392

>NTDB_id=976035 ACM3H0_RS06535 WP_001874060.1 1216281..1216742(-) (comGF) [Streptococcus agalactiae strain M14]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=976035 ACM3H0_RS06535 WP_001874060.1 1216281..1216742(-) (comGF) [Streptococcus agalactiae strain M14]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTCGAAGGCGCTCACTTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAAACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373