Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   ACM3H0_RS06525 Genome accession   NZ_CP180685
Coordinates   1214843..1215817 (-) Length   324 a.a.
NCBI ID   WP_001008570.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain M14     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1209843..1220817
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACM3H0_RS06490 (ACM3H0_06490) pepA 1209907..1210974 (+) 1068 WP_001281321.1 glutamyl aminopeptidase -
  ACM3H0_RS06495 (ACM3H0_06495) proC 1211044..1211814 (+) 771 WP_001867096.1 pyrroline-5-carboxylate reductase -
  ACM3H0_RS06500 (ACM3H0_06500) - 1211835..1212500 (-) 666 WP_000008111.1 CPBP family intramembrane glutamic endopeptidase -
  ACM3H0_RS06505 (ACM3H0_06505) - 1212569..1213024 (-) 456 WP_000905674.1 hypothetical protein -
  ACM3H0_RS06510 (ACM3H0_06510) - 1213065..1213202 (-) 138 WP_001867090.1 hypothetical protein -
  ACM3H0_RS06515 (ACM3H0_06515) - 1213261..1213467 (-) 207 WP_000798242.1 helix-turn-helix transcriptional regulator -
  ACM3H0_RS06520 (ACM3H0_06520) - 1213618..1214811 (-) 1194 WP_000047535.1 acetate kinase -
  ACM3H0_RS06525 (ACM3H0_06525) comGH 1214843..1215817 (-) 975 WP_001008570.1 class I SAM-dependent methyltransferase Machinery gene
  ACM3H0_RS06530 (ACM3H0_06530) comGG 1215932..1216303 (-) 372 WP_000601104.1 competence type IV pilus minor pilin ComGG Machinery gene
  ACM3H0_RS06535 (ACM3H0_06535) comGF 1216281..1216742 (-) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF Machinery gene
  ACM3H0_RS06540 (ACM3H0_06540) comGE 1216696..1216995 (-) 300 WP_001867089.1 competence type IV pilus minor pilin ComGE Machinery gene
  ACM3H0_RS06545 (ACM3H0_06545) comGD 1216967..1217395 (-) 429 WP_000793381.1 competence type IV pilus minor pilin ComGD Machinery gene
  ACM3H0_RS06550 (ACM3H0_06550) comGB 1217392..1218435 (-) 1044 WP_223295592.1 competence type IV pilus assembly protein ComGB Machinery gene
  ACM3H0_RS06555 (ACM3H0_06555) comGA 1218329..1219300 (-) 972 WP_000250808.1 competence type IV pilus ATPase ComGA Machinery gene
  ACM3H0_RS06560 (ACM3H0_06560) - 1219473..1219838 (-) 366 WP_000285373.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 37100.99 Da        Isoelectric Point: 4.4041

>NTDB_id=976033 ACM3H0_RS06525 WP_001008570.1 1214843..1215817(-) (comGH) [Streptococcus agalactiae strain M14]
MNFEKIETAYELILENIQTIENQLKTHIYDALIEQNSYYLGSSCDLDIVVVNNQKLRQLDLSQEEWRRTFQFIFIKSAQT
EQLQANHQFTPDSIGFILLFLLEELTSQETVDVLEIGSGTGNLAQTLLNNSSKELNYMGIEVDDLLIDLSASIAEIIGSS
AQFIQEDAVRPQILKESDVIISDLPIGYYPNDDIAKRYAVSSSKEHTYAHHLLMEQSLKYLKKDGIAIFLAPENLLTSPQ
SDLLKEWLKGYADVIAVLTLPETIFGSRQNAKSIFVLKKQAEQKPETFVYPLTDLQNRENMANFIENFQKWSRENSHYSK
NMIE

Nucleotide


Download         Length: 975 bp        

>NTDB_id=976033 ACM3H0_RS06525 WP_001008570.1 1214843..1215817(-) (comGH) [Streptococcus agalactiae strain M14]
ATGAATTTTGAAAAAATTGAGACAGCCTATGAGCTGATTTTAGAAAATATCCAAACGATTGAGAACCAATTAAAAACTCA
TATTTATGATGCCTTAATTGAACAGAACTCTTATTACCTTGGTTCAAGTTGTGATTTAGATATTGTTGTGGTGAATAACC
AAAAATTACGTCAACTTGACTTAAGTCAAGAAGAATGGCGTCGCACTTTCCAGTTCATTTTTATCAAATCTGCGCAAACA
GAGCAATTACAAGCTAATCATCAGTTTACGCCAGATAGTATTGGTTTTATCTTGTTATTTCTTTTGGAAGAATTAACGAG
TCAAGAGACAGTGGATGTCTTGGAAATTGGAAGTGGAACTGGGAATTTAGCTCAGACTCTCCTCAATAACAGCTCGAAAG
AGTTAAATTATATGGGCATTGAAGTTGATGATCTTTTGATTGATCTATCAGCAAGCATTGCTGAAATTATAGGTTCTAGT
GCCCAATTTATCCAAGAGGATGCCGTTAGACCACAAATTTTGAAAGAAAGCGATGTAATCATTAGTGATTTACCAATTGG
CTATTATCCTAATGATGATATTGCTAAACGATATGCTGTATCAAGTTCTAAAGAGCACACCTATGCTCACCATCTATTGA
TGGAGCAATCTCTTAAATATTTGAAAAAAGATGGAATCGCTATATTTTTAGCACCCGAAAACCTTTTAACAAGTCCACAA
AGTGATTTGCTGAAGGAGTGGTTAAAAGGATATGCAGATGTCATTGCCGTTTTAACTCTACCAGAAACTATTTTTGGAAG
TCGTCAAAATGCGAAATCTATATTTGTTCTCAAGAAGCAAGCAGAACAAAAACCAGAAACCTTTGTATATCCGCTGACAG
ATTTGCAAAATCGTGAGAATATGGCAAACTTCATTGAAAATTTTCAAAAATGGAGCAGAGAAAATAGTCATTACTCAAAA
AATATGATAGAATAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(70-303)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

66.984

97.222

0.651
  comGH Streptococcus mutans UA140

66.984

97.222

0.651