Detailed information NTG0097551

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: R8775_RS02655
• Genome accession: NZ_AP026915
• Coordinates: 503104..503841 (+)
• Length: 245 a.a.
• NCBI ID: WP_001219137.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain PZ900700005
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 498104..508841

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R8775_RS02620	-	499079..499273 (-)	195	WP_001808905.1	hypothetical protein	-
R8775_RS02625 (PC0005_05110)	-	499435..499722 (-)	288	WP_000777753.1	hypothetical protein	-
R8775_RS02630 (PC0005_05120)	-	499732..500142 (-)	411	WP_001278304.1	HIT family protein	-
R8775_RS02635 (PC0005_05130)	pptA	500210..500941 (+)	732	WP_000889923.1	ABC transporter ATP-binding protein	Regulator
R8775_RS02640 (PC0005_05140)	-	500938..501987 (+)	1050	WP_000653751.1	ABC transporter permease	-
R8775_RS02645 (PC0005_05150)	-	502155..502484 (-)	330	WP_000132572.1	hypothetical protein	-
R8775_RS02650 (PC0005_05160)	-	502761..503099 (+)	339	WP_044792896.1	LytTR family DNA-binding domain-containing protein	-
R8775_RS02655 (PC0005_05170)	comE/blpR	503104..503841 (+)	738	WP_001219137.1	LytTR family DNA-binding domain-containing protein	Regulator
R8775_RS02660 (PC0005_05180)	-	503855..505195 (+)	1341	WP_001099893.1	sensor histidine kinase	-
R8775_RS02665 (PC0005_05190)	blpC	505239..505394 (-)	156	WP_000358811.1	quorum-sensing system pheromone BlpC	-
R8775_RS02670 (PC0005_05200)	-	505451..506812 (-)	1362	WP_050233594.1	bacteriocin secretion accessory protein	-
R8775_RS02675 (PC0005_05210)	comA/nlmT	506823..506987 (-)	165	WP_306420852.1	hypothetical protein	Regulator
R8775_RS02680 (PC0005_05220)	blpA	507197..508498 (-)	1302	Protein_529	peptide cleavage/export ABC transporter BlpA	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28768.92 Da
• Isoelectric Point: 6.2366

>NTDB_id=97551 R8775_RS02655 WP_001219137.1 503104..503841(+) (comE/blpR) [Streptococcus pneumoniae strain PZ900700005]
MRIFVLEDDFSQQTRIETTIEKLLKEHHITLSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANGQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide

• Length: 738 bp

>NTDB_id=97551 R8775_RS02655 WP_001219137.1 503104..503841(+) (comE/blpR) [Streptococcus pneumoniae strain PZ900700005]
ATGAGAATATTTGTTTTAGAGGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTCTTGAAGGAACA
TCATATCACTCTGAGTTCTTTTGAAGTTTTTGGTAAGCCAGATCAATTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGATATTGAGATTCGAAATGAGGAGATGAAGGGTCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAT
CCGTATGCCCTGATTGTCTTTGTGACGACTCACTCGGAGTTTATGCCCCTGTCCTTTCGCTACCAAGTGTCTGCTCTGGA
CTATATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATGGTCAAGACA
GTAAAAGTCTAGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCTCAATTCCAGTATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (3-122)

• LytTr DNA-binding domain (LytTR) (151-241)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.441	100	0.539
comE/comE1	Streptococcus equinus JB1	43.038	96.735	0.416
comE/comE2	Streptococcus equinus JB1	38.43	98.776	0.38