Detailed information NTG0972975

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: AAAF57_RS07520
• Genome accession: NZ_CP150847
• Coordinates: 1641881..1642624 (+)
• Length: 247 a.a.
• NCBI ID: WP_101799772.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS5
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1636881..1647624

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AAAF57_RS07490 (AAAF57_07530)	-	1637176..1637502 (-)	327	WP_410537225.1	LysR substrate-binding domain-containing protein	-
AAAF57_RS07495 (AAAF57_07535)	-	1637539..1637664 (-)	126	Protein_1463	LysR family transcriptional regulator	-
AAAF57_RS07500 (AAAF57_07540)	-	1637674..1639227 (-)	1554	WP_037605638.1	BCCT family transporter	-
AAAF57_RS07505 (AAAF57_07545)	-	1639455..1640036 (-)	582	WP_195968915.1	type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein	-
AAAF57_RS07510 (AAAF57_07550)	-	1640094..1640303 (-)	210	Protein_1466	CHAP domain-containing protein	-
AAAF57_RS07515 (AAAF57_07555)	-	1640677..1640934 (-)	258	Protein_1467	type II toxin-antitoxin system Phd/YefM family antitoxin	-
AAAF57_RS07520 (AAAF57_07560)	comE/blpR	1641881..1642624 (+)	744	WP_101799772.1	response regulator transcription factor	Regulator
AAAF57_RS07525 (AAAF57_07565)	-	1642634..1643941 (+)	1308	WP_410536420.1	sensor histidine kinase	-
AAAF57_RS07530 (AAAF57_07570)	-	1644181..1644747 (-)	567	WP_410536422.1	transcriptional regulator	-
AAAF57_RS07535 (AAAF57_07575)	rplL	1645533..1645901 (-)	369	WP_004183006.1	50S ribosomal protein L7/L12	-
AAAF57_RS07540 (AAAF57_07580)	rplJ	1645976..1646479 (-)	504	WP_003095623.1	50S ribosomal protein L10	-

Sequence

Protein

• Length: 247 a.a.
• Molecular weight: 28652.06 Da
• Isoelectric Point: 6.2541

>NTDB_id=972975 AAAF57_RS07520 WP_101799772.1 1641881..1642624(+) (comE/blpR) [Streptococcus salivarius strain KSS5]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMNKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLFRCHRSFIVNPENIVKINKEEKMVVFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide

• Length: 744 bp

>NTDB_id=972975 AAAF57_RS07520 WP_101799772.1 1641881..1642624(+) (comE/blpR) [Streptococcus salivarius strain KSS5]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACGCGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCGAAAGAAATTCGAAAAAAA
GATCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATCGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGAATAAAA
TGGGTGCTACTATTGCCCAAGATTCATTTACTTTTGAAACAGCTACGGCTCAAGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACGTCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGAATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGATGACCGCCTATTTAGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAAGATCA
ATAAAGAAGAGAAAATGGTAGTGTTTGAAAATAATAATGAATGTCCCATTTCCCGTACGAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTTTGAAAAGCTAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-241)

• Response regulator receiver domain (Response_reg) (4-123)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.393	96.761	0.526
comE/comE1	Streptococcus equinus JB1	45.679	98.381	0.449
comE/comE2	Streptococcus equinus JB1	39.837	99.595	0.397
comE/comE2	Streptococcus gordonii strain NCTC7865	38.057	100	0.381
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	38.057	100	0.381