Detailed information    

insolico Bioinformatically predicted

Overview

Name   stkP/pknB   Type   Regulator
Locus tag   AAAF57_RS03020 Genome accession   NZ_CP150847
Coordinates   589842..591713 (+) Length   623 a.a.
NCBI ID   WP_410536951.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS5     
Function   activate comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 584842..596713
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAAF57_RS03005 (AAAF57_03005) fmt 586814..587749 (+) 936 WP_073687877.1 methionyl-tRNA formyltransferase -
  AAAF57_RS03010 (AAAF57_03010) rsmB 587739..589061 (+) 1323 WP_410536949.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  AAAF57_RS03015 (AAAF57_03015) - 589105..589842 (+) 738 WP_037598574.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  AAAF57_RS03020 (AAAF57_03020) stkP/pknB 589842..591713 (+) 1872 WP_410536951.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  AAAF57_RS03025 (AAAF57_03025) - 591861..592619 (+) 759 WP_410536953.1 potassium channel family protein -
  AAAF57_RS03030 (AAAF57_03030) liaF 592782..593480 (+) 699 WP_013990238.1 cell wall-active antibiotics response protein LiaF -
  AAAF57_RS03035 (AAAF57_03035) - 593477..594487 (+) 1011 WP_013990239.1 sensor histidine kinase -
  AAAF57_RS03040 (AAAF57_03040) - 594477..595121 (+) 645 WP_002884791.1 response regulator transcription factor -
  AAAF57_RS03055 (AAAF57_03055) rimM 595813..596331 (+) 519 WP_002884411.1 ribosome maturation factor RimM -

Sequence

Protein


Download         Length: 623 a.a.        Molecular weight: 67731.33 Da        Isoelectric Point: 6.3366

>NTDB_id=972959 AAAF57_RS03020 WP_410536951.1 589842..591713(+) (stkP/pknB) [Streptococcus salivarius strain KSS5]
MIQVGKLFAGRYRILKSIGRGGMADVYLANDLILDNEEVAIKVLRTNYQTDQVAVARFQREARAMAELSHPNIVAIRDIG
EEDGQQFLVMEYVDGSDLKKYIQDHAPLSNQDVVRIMGEVLSAMTLAHQKGIIHRDLKPQNVLLTKDGTAKVTDFGIAVA
FAETSLTQTNSMLGSVHYLSPEQARGSKATIQSDIYAMGIMLFEMLTGHIPYDGDSAVTIALQHFQKPLPSILAENRNVP
QALENVVIRATAKKLENRYNSTLEMSRDLVTSLHPSHRRDAKVVFDDMTDTKTLPKVDPVPSASLEKKAVAAEPSEPTPA
PSKQPRKKTTPAKKKKKNFFSTLLKVFLGLVFIGIIIFAYLVFTNPDNVQVPNVAGQELSTAQTKIEGAGFKVGEVKEVE
DDSVDTGKVIKTDPTAGTTRKEGSSIDVYVSSGSKGFALKDYKGKNYKDAIEDLTSNYGVSEDQIDIQHVEDDSAEEGEI
LSQSPGKNKSFNPKDSKAKIKFRVATPKTVTMPDVTGLTVSTAVQTLNRKSISSSSIEYHDYNTGAKLDKDKVPSSTEVL
YQDPQAGTSVDGTVILYVSVATASSSLQSSSSSTTHSSSTSSSTDSTTSSTETSTEATHTELQ

Nucleotide


Download         Length: 1872 bp        

>NTDB_id=972959 AAAF57_RS03020 WP_410536951.1 589842..591713(+) (stkP/pknB) [Streptococcus salivarius strain KSS5]
ATGATCCAAGTTGGCAAATTGTTTGCTGGACGTTATCGAATCCTTAAATCTATCGGACGTGGTGGTATGGCGGATGTTTA
TCTGGCTAATGACCTGATTCTGGATAATGAAGAAGTGGCCATTAAGGTCCTTCGTACCAATTACCAAACAGATCAGGTGG
CTGTGGCGCGTTTTCAGCGTGAAGCGCGTGCCATGGCAGAACTCAGTCATCCTAATATCGTTGCTATCCGAGATATTGGC
GAAGAAGACGGCCAGCAGTTCTTGGTGATGGAGTATGTGGACGGTTCGGACTTGAAGAAATACATTCAAGACCATGCGCC
ACTTTCTAACCAAGATGTTGTGCGTATCATGGGGGAGGTTCTTTCCGCCATGACTCTTGCCCATCAAAAGGGCATTATCC
ACCGTGACCTTAAGCCACAAAACGTTCTTTTAACTAAGGACGGTACAGCCAAGGTCACAGACTTCGGAATTGCGGTTGCC
TTTGCAGAGACTAGTCTAACTCAAACCAACTCTATGTTGGGTTCTGTCCACTACCTCTCACCAGAGCAGGCTCGTGGATC
TAAAGCGACTATCCAAAGTGACATCTATGCTATGGGTATTATGCTTTTTGAAATGTTAACAGGTCATATTCCTTATGATG
GCGATAGTGCGGTAACCATTGCACTCCAACATTTCCAAAAGCCACTCCCATCGATTTTGGCAGAGAACCGTAACGTTCCC
CAAGCCTTGGAAAACGTGGTTATTCGAGCAACAGCCAAAAAATTAGAAAATCGTTATAATAGTACTTTGGAAATGAGCCG
TGACTTGGTAACGAGTTTGCATCCTAGTCATCGACGCGATGCCAAGGTAGTCTTTGATGATATGACGGATACCAAGACCT
TACCGAAGGTTGATCCAGTTCCATCAGCAAGCCTTGAGAAAAAGGCCGTTGCTGCTGAGCCATCAGAGCCTACACCTGCT
CCAAGTAAACAACCGAGGAAGAAAACGACACCAGCTAAGAAGAAAAAGAAGAATTTCTTCTCAACCTTACTCAAGGTTTT
CCTAGGACTTGTCTTTATTGGTATTATCATCTTTGCCTATTTGGTATTTACCAATCCTGATAATGTCCAGGTGCCTAATG
TGGCCGGTCAAGAGTTGTCCACAGCTCAGACTAAAATTGAGGGTGCTGGATTTAAGGTAGGAGAAGTTAAGGAAGTGGAA
GATGACTCTGTCGATACAGGCAAGGTCATCAAGACTGATCCTACAGCTGGAACCACACGAAAAGAAGGATCAAGCATTGA
TGTCTATGTTTCTTCTGGTAGTAAAGGTTTTGCGTTGAAAGACTACAAAGGTAAAAACTACAAAGATGCCATTGAGGACT
TAACTTCGAATTATGGCGTTTCTGAGGACCAAATTGATATTCAGCATGTCGAAGACGACAGTGCTGAAGAGGGAGAAATC
CTATCTCAAAGTCCAGGGAAAAACAAGTCTTTCAATCCTAAGGATAGTAAGGCCAAGATTAAGTTCCGTGTGGCAACTCC
TAAGACAGTTACCATGCCTGATGTGACTGGTTTGACTGTTTCAACAGCGGTTCAAACCTTGAATCGTAAGAGTATCTCAA
GTAGTAGTATCGAGTATCATGACTATAATACTGGTGCCAAGTTAGACAAGGATAAGGTTCCTAGCAGTACAGAGGTCCTT
TATCAAGATCCACAAGCTGGTACAAGTGTTGATGGTACAGTGATTCTCTATGTTTCAGTTGCAACAGCAAGTTCAAGTCT
ACAGTCAAGCTCAAGCAGTACGACACATTCGTCATCGACGAGCTCAAGTACTGACAGTACAACTTCAAGCACTGAAACCT
CGACAGAGGCTACTCACACAGAGCTACAGTAG

Domains

Predicted by InterproScan.

Protein kinase domain (Pkinase)

(12-235)

PASTA domain (PASTA)

(510-579)

PASTA domain (PASTA)

(369-431)

PASTA domain (PASTA)

(440-504)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  stkP/pknB Streptococcus salivarius strain HSISS4

98.718

100

0.989
  pknB Streptococcus mutans UA159

67.343

86.998

0.586
  stkP Streptococcus pneumoniae TIGR4

52.414

93.098

0.488
  stkP Streptococcus pneumoniae D39

52.241

93.098

0.486
  stkP Streptococcus pneumoniae R6

52.241

93.098

0.486
  stkP Streptococcus pneumoniae Rx1

52.069

93.098

0.485

Multiple sequence alignment