Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   AAAF57_RS00800 Genome accession   NZ_CP150847
Coordinates   154493..155593 (+) Length   366 a.a.
NCBI ID   WP_148263031.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS5     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 149493..160593
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AAAF57_RS00790 (AAAF57_00790) - 153228..153590 (+) 363 WP_014635121.1 DUF1033 family protein -
  AAAF57_RS00795 (AAAF57_00795) comGA/cglA/cilD 153670..154611 (+) 942 WP_002887018.1 competence type IV pilus ATPase ComGA Machinery gene
  AAAF57_RS00800 (AAAF57_00800) comYB 154493..155593 (+) 1101 WP_148263031.1 competence type IV pilus assembly protein ComGB Machinery gene
  AAAF57_RS00805 (AAAF57_00805) comYC 155602..155916 (+) 315 WP_037611125.1 competence type IV pilus major pilin ComGC Machinery gene
  AAAF57_RS00810 (AAAF57_00810) comYD 155876..156304 (+) 429 WP_270334813.1 competence type IV pilus minor pilin ComGD Machinery gene
  AAAF57_RS00815 (AAAF57_00815) comGE 156336..156566 (+) 231 WP_021144685.1 competence type IV pilus minor pilin ComGE -
  AAAF57_RS00820 (AAAF57_00820) comYF 156553..156990 (+) 438 WP_227071977.1 competence type IV pilus minor pilin ComGF Machinery gene
  AAAF57_RS00825 (AAAF57_00825) comGG 156968..157285 (+) 318 WP_227071976.1 competence type IV pilus minor pilin ComGG -
  AAAF57_RS00830 (AAAF57_00830) comYH 157330..158286 (+) 957 WP_227071975.1 class I SAM-dependent methyltransferase Machinery gene
  AAAF57_RS00835 (AAAF57_00835) - 158343..159536 (+) 1194 WP_002885831.1 acetate kinase -
  AAAF57_RS00840 (AAAF57_00840) - 159789..159986 (+) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -

Sequence

Protein


Download         Length: 366 a.a.        Molecular weight: 41650.75 Da        Isoelectric Point: 10.1478

>NTDB_id=972936 AAAF57_RS00800 WP_148263031.1 154493..155593(+) (comYB) [Streptococcus salivarius strain KSS5]
MPVKISKATRQPAGTSSWKAWLNKDISLKGISKGKKLKINQQLKVIQLFKQLLKAGFTLTEIVAFLERSHLLKESSLSLM
KASLMRGDRLDQMFASVGFSDNIVTQIALADKHGNLLGSLTKIETYMLRMTKVRKKLMEVATYPILLLGFLILIMLGLKN
YLLPQLLEGDGKENWAVQLVQIFPQLFFVTLCGLLVLSLILYLWVKRQPALVFYRRMAKIPFIGQTVRLYTTAYYAREWG
NLLGQGIDLLDLVALMKEQKSKLFRELGTDLEEALMLGQSFPDRIASHPFFTKELSLIIAYGEANARLGYELEVYAEEVW
QAFFNRLNKATTFVQPLIFVIVAVVIVMIYAAMLLPMYQNMEGMMS

Nucleotide


Download         Length: 1101 bp        

>NTDB_id=972936 AAAF57_RS00800 WP_148263031.1 154493..155593(+) (comYB) [Streptococcus salivarius strain KSS5]
TTGCCAGTGAAAATTTCCAAAGCCACTCGTCAACCAGCTGGAACCAGCAGTTGGAAGGCTTGGTTAAACAAGGATATCTC
ACTGAAGGGGATATCCAAGGGGAAAAAATTAAAGATTAATCAGCAACTCAAGGTTATCCAGCTTTTCAAACAACTTCTAA
AGGCAGGGTTTACCTTAACTGAAATCGTAGCCTTTTTGGAGCGAAGTCACTTGTTGAAAGAATCGTCCTTGTCTCTTATG
AAAGCGAGTTTAATGCGAGGCGACAGGTTGGACCAGATGTTTGCGTCAGTAGGTTTTTCGGACAATATTGTTACTCAGAT
TGCCCTTGCTGATAAGCACGGTAATCTTCTAGGGAGTTTAACCAAGATTGAAACCTACATGCTTCGTATGACCAAGGTTC
GTAAGAAACTCATGGAGGTAGCGACCTATCCTATTCTACTTCTGGGGTTCCTGATTCTGATTATGTTGGGGCTCAAAAAT
TATCTTTTACCTCAATTGTTAGAGGGGGATGGTAAGGAGAATTGGGCTGTACAGTTGGTTCAGATTTTTCCCCAGCTCTT
TTTTGTGACTTTGTGCGGACTGCTTGTATTAAGCTTAATTCTCTATCTATGGGTGAAACGCCAGCCAGCCCTTGTCTTTT
ATCGACGAATGGCAAAAATCCCTTTTATAGGCCAAACTGTCAGGCTATATACGACCGCCTATTATGCTAGAGAATGGGGA
AATCTCTTAGGGCAAGGTATTGACTTGCTAGACTTGGTTGCTCTAATGAAAGAGCAAAAGTCCAAGCTCTTTCGTGAGCT
GGGGACTGATTTAGAAGAAGCCTTGATGCTAGGACAGAGTTTTCCTGACCGTATTGCTAGTCACCCTTTCTTCACTAAGG
AACTATCCTTAATTATTGCTTATGGAGAGGCTAATGCTAGGTTGGGCTATGAGTTAGAAGTCTATGCTGAAGAGGTTTGG
CAGGCTTTCTTTAACCGTCTTAATAAGGCAACAACCTTTGTGCAACCCCTCATTTTTGTTATTGTTGCTGTCGTGATTGT
AATGATCTATGCAGCTATGCTATTACCAATGTATCAAAATATGGAAGGAATGATGTCATGA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(51-164)

Type II secretion system (T2SS), protein F (T2SSF)

(236-356)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

55.102

93.716

0.516
  comYB Streptococcus mutans UA159

55.102

93.716

0.516
  comYB Streptococcus gordonii str. Challis substr. CH1

51.603

93.716

0.484
  comGB/cglB Streptococcus mitis NCTC 12261

50.147

92.623

0.464
  comGB/cglB Streptococcus mitis SK321

49.408

92.35

0.456
  comGB/cglB Streptococcus pneumoniae Rx1

49.112

92.35

0.454
  comGB/cglB Streptococcus pneumoniae D39

49.112

92.35

0.454
  comGB/cglB Streptococcus pneumoniae R6

49.112

92.35

0.454
  comGB/cglB Streptococcus pneumoniae TIGR4

49.112

92.35

0.454
  comGB Lactococcus lactis subsp. cremoris KW2

44.681

89.891

0.402

Multiple sequence alignment