Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACJVG6_RS10615 Genome accession   NZ_CP177180
Coordinates   2234904..2235647 (-) Length   247 a.a.
NCBI ID   WP_002887222.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD-KRBY     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2229904..2240647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVG6_RS10600 - 2231010..2231683 (+) 674 Protein_2029 transposase -
  ACJVG6_RS10605 - 2231955..2232299 (+) 345 Protein_2030 transposase -
  ACJVG6_RS10610 - 2233587..2234894 (-) 1308 WP_002887221.1 sensor histidine kinase -
  ACJVG6_RS10615 comE/blpR 2234904..2235647 (-) 744 WP_002887222.1 response regulator transcription factor Regulator
  ACJVG6_RS10620 tnpA 2236458..2236931 (+) 474 Protein_2033 IS200/IS605 family transposase -
  ACJVG6_RS10625 - 2237636..2237831 (+) 196 Protein_2034 IS30 family transposase -
  ACJVG6_RS10630 - 2238123..2239553 (+) 1431 WP_002887226.1 hypothetical protein -
  ACJVG6_RS10635 - 2239546..2240529 (+) 984 WP_002887227.1 hypothetical protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28700.12 Da        Isoelectric Point: 6.2541

>NTDB_id=969658 ACJVG6_RS10615 WP_002887222.1 2234904..2235647(-) (comE/blpR) [Streptococcus salivarius strain MRD-KRBY]
MLNIFILEDEFLQQTRIETVIKDVIAKKSLKCKGPEIFGKPSQLLDAITERGSHQLFFLDIEIKGEEKKGLDIAKEIRKK
DPNATIVFVTTHSEFMPVTFKYRVAALDFIDKALDDEDFYERVHLAIEYTMNKMGATIAQDSFTFETATAQVQVPFNNIL
FFETSPTIHKVILHTKEERMEFYASISEVERADDRLYRCHRSFIVNPENIVKINKEEKMVMFENNNECPISRTKYKGLLE
KVKSLKS

Nucleotide


Download         Length: 744 bp        

>NTDB_id=969658 ACJVG6_RS10615 WP_002887222.1 2234904..2235647(-) (comE/blpR) [Streptococcus salivarius strain MRD-KRBY]
TTGTTAAATATTTTTATTTTAGAAGACGAATTTTTACAACAAACACGAATAGAGACCGTTATTAAGGATGTTATTGCAAA
AAAATCTCTAAAATGTAAAGGACCTGAGATTTTTGGAAAACCTAGCCAGCTACTTGATGCGATTACCGAAAGAGGTTCTC
ATCAACTTTTCTTTTTAGATATTGAAATTAAAGGAGAAGAAAAAAAGGGGCTAGACATTGCGAAAGAAATCCGAAAAAAA
GACCCTAATGCAACAATTGTTTTTGTAACAACACATTCAGAATTTATGCCAGTCACTTTTAAATATAGAGTTGCTGCACT
AGATTTTATCGATAAAGCTTTGGATGATGAAGATTTTTATGAACGTGTTCATTTAGCAATTGAATATACCATGAATAAAA
TGGGTGCTACTATTGCCCAAGATTCATTTACTTTTGAAACGGCTACGGCTCAAGTTCAAGTTCCTTTTAACAATATCTTA
TTTTTTGAAACGTCTCCAACAATACATAAAGTTATTTTGCATACTAAAGAAGAACGCATGGAGTTCTACGCCAGTATTTC
AGAAGTTGAACGAGCTGACGACCGCCTATATCGATGCCATCGTTCATTTATCGTTAATCCTGAAAATATCGTTAAGATCA
ATAAAGAAGAGAAAATGGTAATGTTTGAAAATAATAATGAATGTCCCATTTCCCGTACGAAATATAAGGGCCTCCTAGAA
AAAGTTAAATCTTTGAAAAGCTAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(152-241)

Response regulator receiver domain (Response_reg)

(4-123)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.975

96.761

0.522
  comE/comE1 Streptococcus equinus JB1

45.679

98.381

0.449
  comE/comE2 Streptococcus equinus JB1

39.431

99.595

0.393
  comE/comE2 Streptococcus gordonii strain NCTC7865

37.652

100

0.377
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

37.652

100

0.377