Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   ACJVG6_RS09300 Genome accession   NZ_CP177180
Coordinates   1969355..1970098 (-) Length   247 a.a.
NCBI ID   WP_002886967.1    Uniprot ID   -
Organism   Streptococcus salivarius strain MRD-KRBY     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1964355..1975098
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ACJVG6_RS09285 - 1965533..1967029 (-) 1497 WP_004183639.1 IS1182 family transposase -
  ACJVG6_RS09290 - 1967210..1968439 (+) 1230 WP_411888485.1 ISL3 family transposase -
  ACJVG6_RS09295 - 1968463..1969203 (-) 741 Protein_1775 IS30 family transposase -
  ACJVG6_RS09300 comE/blpR 1969355..1970098 (-) 744 WP_002886967.1 response regulator transcription factor Regulator
  ACJVG6_RS09305 - 1970100..1971416 (-) 1317 WP_002886968.1 GHKL domain-containing protein -
  ACJVG6_RS09310 - 1971440..1972720 (-) 1281 WP_002886971.1 hypothetical protein -
  ACJVG6_RS09315 - 1972742..1973632 (-) 891 WP_002886972.1 hypothetical protein -
  ACJVG6_RS09320 - 1973687..1974994 (-) 1308 WP_002886973.1 GHKL domain-containing protein -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28533.89 Da        Isoelectric Point: 7.0533

>NTDB_id=969635 ACJVG6_RS09300 WP_002886967.1 1969355..1970098(-) (comE/blpR) [Streptococcus salivarius strain MRD-KRBY]
MNIYILEDDLMQQTRISDIIRELVSEGAFSVRKLEVFSKPHKLLSSINEKGNHQIFLLDIDIDGNRKKGLEVASEIRQQD
ANAVIIFVTTHSEFAPISFKYKVSALDFIEKTVSNVEFKQQLKQTLTFVNQKIGDVDDDEMFVFETAQSRIQVPMRDIYY
FATAATPHKVMLITKTERLEFYANLGDITSVNKILFSCHRSFLVNLDNIARIDKTQLMIYFENGDSCPVSRLKMKALLKK
WSEVRNH

Nucleotide


Download         Length: 744 bp        

>NTDB_id=969635 ACJVG6_RS09300 WP_002886967.1 1969355..1970098(-) (comE/blpR) [Streptococcus salivarius strain MRD-KRBY]
ATGAATATATATATATTAGAAGATGATTTGATGCAACAAACACGTATTAGTGATATCATCAGAGAATTGGTTTCAGAGGG
TGCGTTTTCTGTACGAAAACTTGAAGTTTTTTCTAAACCACATAAACTATTGTCCAGCATCAACGAGAAGGGGAACCATC
AGATTTTTCTTTTGGATATTGATATTGATGGCAATCGAAAGAAGGGGTTAGAAGTTGCCTCTGAAATTCGTCAACAAGAT
GCTAATGCGGTTATTATTTTTGTAACAACTCACTCAGAATTTGCTCCAATTAGTTTTAAGTATAAGGTTTCCGCACTTGA
TTTTATTGAAAAGACAGTCTCTAATGTGGAATTCAAACAACAATTGAAACAAACCTTGACTTTTGTAAATCAAAAAATTG
GAGATGTGGACGATGATGAGATGTTTGTGTTTGAAACTGCTCAGTCTAGAATACAAGTTCCGATGCGAGATATTTATTAT
TTTGCGACAGCTGCAACTCCTCATAAGGTAATGTTAATTACTAAAACAGAGCGCCTGGAGTTTTATGCTAATCTTGGAGA
TATTACTTCGGTGAATAAAATACTCTTTTCATGTCACCGCTCCTTTTTAGTTAATCTGGATAATATTGCCCGTATTGATA
AGACGCAACTGATGATTTATTTTGAGAATGGTGATTCATGTCCGGTTTCTCGCTTGAAAATGAAGGCCCTACTTAAAAAA
TGGTCAGAGGTAAGAAATCATTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

47.083

97.166

0.457
  comE/comE2 Streptococcus equinus JB1

41.633

99.19

0.413
  comE/comE1 Streptococcus equinus JB1

39.669

97.976

0.389
  comE/comE2 Streptococcus gordonii strain NCTC7865

36.929

97.571

0.36
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

36.929

97.571

0.36

Multiple sequence alignment